Drugs News and Research

RSS

A precursor to remdesivir shows therapeutic potential for COVID-19

A new study points to the potential to use the remdesivir precursor, GS-441524, as a treatment choice for COVID-19.

9 Feb 2021

Study identifies major flaws in iBMEC-based models of the blood-brain barrier

A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.

9 Feb 2021

New platform could help advance genomic medicine research, drug discovery

A Cleveland Clinic-led team of researchers has developed a personalized genomic medicine platform that will help advance accelerate genomic medicine research and genome-informed drug discovery, according to new study results published recently in Genome Biology.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

8 Feb 2021

Researchers identify a new drug target for Ebola, Marburg viruses

Ebola and Marburg are among the most deadly viruses, with mortality rates from these infections ranging from 25% to 90%.

8 Feb 2021

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown.

8 Feb 2021

Is a ten day isolation period for COVID-19 patients long enough?

In a new study researchers at the Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, Brazil, reported that mild COVID-19 patients can still be infectious at day 10 from the illness onset, even in the absence of symptoms.

8 Feb 2021

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

A recent study describes the experimental selection of SARS-CoV-2 mutants associated with resistance to antibodies, with important implications for vaccine development and therapeutic antibody use.

8 Feb 2021

Novel method instructs immune cells to help repair damaged tissues in the intestine

A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University.

8 Feb 2021

New wearable sensor uses nanomaterials technology to detect illegal drugs in sweat

Researchers in South Korea have successfully developed a wearable sensor that can detect illegal drugs in sweat by using nanomaterials technology that amplify the optical signal of narcotics to a flexible, body-worn material.

8 Feb 2021

Scientists grow small intestinal cells from human-induced pluripotent stem cells

A team of scientists from Japan have found success in growing small intestinal cells, akin to those found in the human body, from human-induced pluripotent stem cells.

8 Feb 2021

Study finds increased substance use, mental health issues in people with obesity during the pandemic

The COVID-19 pandemic is having a detrimental impact on substance use, mental health, and weight-related health behaviors among people with obesity, according to a new study by researchers at UT Southwestern and the UTHealth School of Public Health.

8 Feb 2021

COVID-19 pandemic and nanotechnology

Writing in the International Journal of Nanomedicine, Professor Dongki Yang, from the Department of Physiology, Gachon University, South Korea, has reviewed the available knowledge on the coronaviruses, current approaches to tackle the newly emerged SARS-CoV-2 infection, and the innovative application of nanotechnology in the COVID-19 pandemic.

8 Feb 2021

New technique reveals cellular forces involved in biological tissue formation and growth

A team of Brown University researchers developed a technique that uses tiny polymer spheres to sense the forces at play as body tissue forms and grows.

8 Feb 2021

In vitro human blood-brain barrier model found to have a critical flaw

Cells used to study the human blood brain barrier in the lab aren't what they seem, throwing nearly a decade's worth of research into question, a new study from scientists at Columbia University Vagelos College of Physicians and Surgeons and Weill Cornell Medicine suggests.

8 Feb 2021

Gut fungi teach the immune system how to respond to their dangerous relatives

Common fungi, often present in the gut, teach the immune system how to respond to their more dangerous relatives, according to new research from scientists at Weill Cornell Medicine. Breakdowns in this process can leave people susceptible to deadly fungal infections.

7 Feb 2021

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

The discovery of an "Achilles heel" in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

6 Feb 2021

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

At the time of writing, coronavirus disease 2019 (COVID-19) is seriously threatening human lives and health throughout the world.

6 Feb 2021

Drugs News and Research

A precursor to remdesivir shows therapeutic potential for COVID-19

Study identifies major flaws in iBMEC-based models of the blood-brain barrier

New platform could help advance genomic medicine research, drug discovery

HIV: New therapeutic approach to restore the effectiveness of immune cells

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

Researchers identify a new drug target for Ebola, Marburg viruses

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Is a ten day isolation period for COVID-19 patients long enough?

SARS-CoV-2 escape mutations identified against monoclonal antibodies and polyclonal immune sera

Novel method instructs immune cells to help repair damaged tissues in the intestine

New wearable sensor uses nanomaterials technology to detect illegal drugs in sweat

Scientists grow small intestinal cells from human-induced pluripotent stem cells

Study finds increased substance use, mental health issues in people with obesity during the pandemic

COVID-19 pandemic and nanotechnology

New technique reveals cellular forces involved in biological tissue formation and growth

In vitro human blood-brain barrier model found to have a critical flaw

Gut fungi teach the immune system how to respond to their dangerous relatives

Discovery of ‘Achilles heel’ in gut bacteria may lead to targeted therapies for Crohn’s disease

Scientists use the knowledge from climate system models to help fight COVID-19 pandemic

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News