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Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell.

6 Jul 2016

Study finds no substantial link between gadolinium exposure and parkinsonism

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

6 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

CDC invests in Donator’s unique heat stabilization technology

Denator, the Swedish-based biotechnology company specialized in biological sample preparation technologies announced today that the Center for Disease Control and Prevention, Atlanta, had made a major purchase of its proprietary heat stabilization technology Stabilizor T1™.

6 Jul 2016

Changes in neural circuit involved in emotional resilience may help youngsters adapt to childhood adversity

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports a neural signature of emotional adaptation that could help researchers understand how the brain adapts to childhood adversity and predict which kids may be vulnerable to developing later psychopathology.

6 Jul 2016

Proscia completes $1M seed round of financing to advance cancer diagnosis, treatment

Proscia Inc., a data solutions provider for digital pathology, announced today the completion of its $1M seed round of financing.

5 Jul 2016

AOSSM presents research awards, grants at annual meeting

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine will present research awards and grants during its Annual Meeting, July 7-10 in Colorado Springs, CO.

5 Jul 2016

FIB-4 index predicts HBV-related HCC

Japanese researchers reveal an association between elevated FIB-4 index 24 weeks after the initiation of nucleos(t)ide analogue therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

4 Jul 2016

MIT engineers develop new way to visualize RNA molecules in higher resolution

Cells contain thousands of messenger RNA molecules, which carry copies of DNA's genetic instructions to the rest of the cell. MIT engineers have now developed a way to visualize these molecules in higher resolution than previously possible in intact tissues, allowing researchers to precisely map the location of RNA throughout cells.

4 Jul 2016

Study provides insight into why individual mycobacteria respond differently to antibiotics

Tuberculosis is one of the most common infectious diseases in the world, infecting almost 10 million people each year. Treating the disease can be challenging and requires a combination of multiple antibiotics delivered over several months.

4 Jul 2016

Scientists reveal how new adult-born neurons evolve in olfactory bulb of mice

Scientists from the Institut Pasteur and the CNRS were able to make real-time observations over a period of several months that reveal how new adult-born neurons are formed and evolve in the olfactory bulb of mice.

4 Jul 2016

Laser-printed micropatterns can serve as platform for diagnostic applications

Laser printouts on paper might be used as a platform for low-cost organic electronics, microfluidic, or sensor applications. German scientists at Humboldt University Berlin have now developed a procedure for the selective coating of laser-printed micropatterns on paper.

4 Jul 2016

Researchers develop computer model for speed analysis of TB's complex life-cycle

Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, is a serious global health problem accounting for 1.3 million worldwide deaths annually.

1 Jul 2016

New software tool could help routinely measure brain atrophy in MS patients

The loss of brain tissue, called brain atrophy, is a normal part of aging, but multiple sclerosis (MS) accelerates the process.

1 Jul 2016

New supplement could help reduce urge to consume high-calorie foods

Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests.

1 Jul 2016

New technique can help identify aggressive forms of DCIS

When a woman is diagnosed with the earliest stage of breast cancer, how aggressive should her treatment be? Will the non-invasive cancer become invasive? Or is it a slow-growing variety that will likely never be harmful?

1 Jul 2016

Researchers observe language learning skills through brain imaging

Learning a new language is a difficult task. It requires skills for memorizing new words, learning how to put those words together in a grammatical way, and integrating them with existing linguistic knowledge.

30 Jun 2016

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature.

From Bruker BioSpin Group 30 Jun 2016

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

The targeted therapy everolimus may be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma according to the results of a pilot study by Mayo Clinic researchers published in the Lancet Haematology.

30 Jun 2016

Imaging News and Research

Researchers use FRET to make activation of AMPA receptors optically visible

Study finds no substantial link between gadolinium exposure and parkinsonism

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

CDC invests in Donator’s unique heat stabilization technology

Changes in neural circuit involved in emotional resilience may help youngsters adapt to childhood adversity

Proscia completes $1M seed round of financing to advance cancer diagnosis, treatment

AOSSM presents research awards, grants at annual meeting

FIB-4 index predicts HBV-related HCC

MIT engineers develop new way to visualize RNA molecules in higher resolution

Study provides insight into why individual mycobacteria respond differently to antibiotics

Scientists reveal how new adult-born neurons evolve in olfactory bulb of mice

Laser-printed micropatterns can serve as platform for diagnostic applications

Researchers develop computer model for speed analysis of TB's complex life-cycle

New software tool could help routinely measure brain atrophy in MS patients

New supplement could help reduce urge to consume high-calorie foods

New technique can help identify aggressive forms of DCIS

Researchers observe language learning skills through brain imaging

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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