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Signs of P.A.D. indicate increased risk of heart disease, heart attack, death

Approximately nine million Americans over the age of 50 are living with a disease that affects their legs and raises their risk of having a heart attack. Unfortunately, many with the disease do not even know they have it. February is Heart Month, and the Vascular Disease Foundation and its P.A.D. Coalition are urging Americans to listen to their legs and be alert to the signs of peripheral arterial disease, or P.A.D.

18 Feb 2011

FDA grants miRagen's MGN-4893 orphan drug designation for treatment of polycythemia vera

miRagen Therapeutics, Inc., a privately-held biopharmaceutical company focused on improving patients' lives by developing innovative microRNA (miRNA)-based therapeutics for cardiovascular and muscle disease, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to the company's compound MGN-4893 for the treatment of polycythemia vera, a myeloproliferative disease characterized by an overabundance of blood cells and platelets in the body.

18 Feb 2011

Acorda reports fourth quarter net revenue of $133.1 million for full year ended December 31, 2010

Acorda Therapeutics, Inc. today announced its financial results for the fourth quarter and full year ended December 31, 2010.

17 Feb 2011

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

In fact, according to new research from Johns Hopkins, the fusion of muscle cells is a power struggle that involves a smaller mobile antagonist that points at, pokes and finally pushes into its larger, stationary partner using a newly identified finger-like projection.

17 Feb 2011

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Amicus Therapeutics today announced that additional positive data from the ongoing Phase 2 extension study of its investigational drug Amigal™ (migalastat HCl) for Fabry disease will be presented at the Lysosomal Disease Network WORLD Symposium in Las Vegas, Nevada, February 16-18th, 2011.

17 Feb 2011

Endo Pharmaceuticals, Bioniche announce first patient enrollment in Urocidin second Phase III trial

Endo Pharmaceuticals and Bioniche Life Sciences Inc., today announced enrollment of the first patient in the second Phase III clinical trial of Urocidin.

16 Feb 2011

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Ebstein's anomaly is a rare congenital valvular heart disease. Now, in patients with this disease, researchers of the Academic Medical Center Amsterdam in the Netherlands, the University of Newcastle, UK and the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have identified mutations in a gene which plays an important role in the structure of the heart.

16 Feb 2011

Researchers identify cell of origin for sarcoma

Researchers at Oregon Health & Science University Doernbecher Children's Hospital have defined the cell of origin for a kind of cancer called sarcoma. In a study published today as the Featured Article in the journal Cancer Cell, they report that childhood and adult sarcomas are linked in their biology, mutations and the cells from which these tumors first start.

16 Feb 2011

Scientists find molecular pathway that offers novel targets for diabetes therapies

Once people develop type 2 diabetes, high blood glucose levels alter their metabolism so much that it becomes difficult to sift through all the clues to find what might enable the disease.

15 Feb 2011

Studies reveal markers for measuring ability of children with ADHD to control impulsive movements

Two research studies published today in Neurology®, the medical journal of the American Academy of Neurology, found markers for measuring the ability of children with Attention Deficit Hyperactivity Disorder (ADHD) to control impulsive movements, which may reveal insights into the neurobiology of ADHD, inform prognosis and guide treatments.

15 Feb 2011

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Targeting the neuroinflammatory causes of Parkinson's disease with a naturally present brain chemical signal could offer a better understanding of the clinical mechanisms of the disease and open a future therapeutic window, reports a team of researchers from the University of South Florida Department Neurosurgery and Brain Repair and the James A. Haley Veterans' Administration Hospital, Tampa.

14 Feb 2011

Janssen, Medivir collaborate to discover and develop drugs against dengue virus

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, announces today that it has signed a collaboration agreement with Janssen Pharmaceutica N.V. for the discovery and development of drugs for the prophylaxis and treatment of dengue virus infection.

14 Feb 2011

Spinal cord sugar residues regulate growth and survival of nerve cells: Study

Researchers in Bochum have found out that certain sugar residues in the spinal cord regulate the growth and survival of nerve cells which control the movement of muscles. "We hope that our findings can improve regenerative treatment of nerve injuries", explains Prof. Dr. Stefan Wiese from the Molecular Cell Biology study group.

14 Feb 2011

Gene GFPT1 crucial in causing variation of Congenital Myasthenic Syndrome

The gene, GFPT1, has been identified by researchers at Newcastle University working with international colleagues, as crucial in causing a variation of Congenital Myasthenic Syndrome (CMS).

11 Feb 2011

Women need good nutrition and regular exercise

Obesity levels are at an all-time high among men, women, and children in the United States. The need for good nutrition and regular exercise is paramount for maintaining proper health and for keeping those extra pounds at bay, especially for women.

11 Feb 2011

Harvard Bioscience's novel bioreactor technology featured on National Geographic Channel

Harvard Bioscience, Inc., a global developer, manufacturer and marketer of a broad range of specialized products used to advance life science research and regenerative medicine, is pleased to announce that its novel bioreactor technology was featured on the National Geographic Channel's Explorer television program on February 7, 2011.

From Harvard Bioscience 11 Feb 2011

RF-induced heat therapy could help treat common parasitic skin infection

Scientists are hoping that heat therapy could eventually replace a complex drug regimen as the first-line treatment of a parasitic skin infection common in tropical and subtropical regions of the world.

11 Feb 2011

Rhabdomyolysis episode at University of Iowa signals a public health crisis

On January 26, 2011, it was reported that 13 University of Iowa football players were affected so severely by rhabdomyolysis that they were hospitalized. Occurrences of rhabdomyolysis—muscle breakdown—are so rare that it suggests an additional causal factor, such as a drug.

10 Feb 2011

Tart cherries can help athletes reduce muscle damage more quickly

Tart cherries could help athletes reduce muscle damage to recover faster from a tough workout, according to new research published in the American College of Sports Medicine's journal Medicine & Science in Sports & Exercise.

10 Feb 2011

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Using skin cells from young patients who have a severe genetic heart defect, Stanford University School of Medicine scientists have generated beating heart cells that carry the same genetic mutation. The newly created human heart cells - cardiomyocytes - allowed the researchers for the first time to examine and characterize the disorder at the cellular level.

10 Feb 2011

Muscle News and Research

Signs of P.A.D. indicate increased risk of heart disease, heart attack, death

FDA grants miRagen's MGN-4893 orphan drug designation for treatment of polycythemia vera

Acorda reports fourth quarter net revenue of $133.1 million for full year ended December 31, 2010

Muscle, aptly enough, is born of cellular bullying, and not mutual consent

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Endo Pharmaceuticals, Bioniche announce first patient enrollment in Urocidin second Phase III trial

Mutations in gene linked to structure of the heart seen in Ebstein's anomaly patients

Researchers identify cell of origin for sarcoma

Scientists find molecular pathway that offers novel targets for diabetes therapies

Studies reveal markers for measuring ability of children with ADHD to control impulsive movements

CX3CL1 signaling chemical can offer better understanding of Parkinson's disease

Janssen, Medivir collaborate to discover and develop drugs against dengue virus

Spinal cord sugar residues regulate growth and survival of nerve cells: Study

Gene GFPT1 crucial in causing variation of Congenital Myasthenic Syndrome

Women need good nutrition and regular exercise

Harvard Bioscience's novel bioreactor technology featured on National Geographic Channel

RF-induced heat therapy could help treat common parasitic skin infection

Rhabdomyolysis episode at University of Iowa signals a public health crisis

Tart cherries can help athletes reduce muscle damage more quickly

Scientists generate beating heart cells from skin cells of young patients with severe genetic heart defect

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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