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Open-access atlas unveils the molecular mechanisms of roundworm aging

A new aging atlas gives scientists an in-depth view of how individual cells and tissues in worms age and how different lifespan-extending strategies might stop the clock.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

Precise protein design offers hope for damaged hearts and kidneys

Using computer-designed proteins, researchers have now shown they are able to direct human stem cells to form new blood vessels in the lab. This milestone in regenerative medicine offers new hope for repairing damaged hearts, kidneys, and other organs.

18 Jun 2024

New research on long COVID prevalence and risk factors

Early in the pandemic, many people who had SARS-Cov-2 infection or COVID-19 began to report that they couldn't shake off their symptoms even after a month or more - unusually long for a viral infection of the upper respiratory tract - or developed new, persistent symptoms soon after the infection cleared.

18 Jun 2024

Nanobody technology revolutionizes food allergy detection methods

Recent advancements show nanobodies from camelid antibodies excel in food allergen detection with superior stability, specificity, and cost-effectiveness. This innovative approach aims to improve accuracy and efficiency, crucial for preventing severe allergic reactions. The study highlights nanobodies' potential in reliable immunoassays, addressing rising food allergies and enhancing safety measures. Food allergies pose significant health risks, affecting millions worldwide, with the prevalence rising over the past decades.

18 Jun 2024

Safety-focused summary of GLP-1 receptor agonists in diabetes, obesity, and beyond

A recent review in Diabetes Care evaluates the efficacy and safety of GLP-1 receptor agonists for type 2 diabetes and obesity, exploring their potential for new medical indications.

18 Jun 2024

New AI tool could revolutionize clinical trial efficiency and cost

Generative Artificial Intelligence (Gen AI) can rapidly and accurately screen patients for clinical trial eligibility, according to a new study from Mass General Brigham researchers. Such technology could make it faster and cheaper to evaluate new treatments and, ultimately, help bring successful ones to patients.

17 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

Rapid test detects brain cancer mutations in cerebrospinal fluid

A test that looks for genetic hallmarks of brain cancers in samples of cerebrospinal fluid can decrease the time to diagnosis and eliminate the need for invasive brain biopsies for some patients.

17 Jun 2024

FQHC patients struggle with food, housing, and transportation insecurity

A first-of-its-kind study found high rates of food insecurity, housing insecurity, financial strain, and/or a lack of transportation among patients at federally qualified health centers, particularly patients who were low-income or from racial/ethnic minority populations.

17 Jun 2024

Innovative bread formulation shows promise in preventing asthma

Brazilian researchers have developed functional bread with the potential to prevent asthma, a respiratory disorder responsible for some 350,000 hospitalizations per year in the SUS (Sistema Único de Saúde), the nation's public healthcare network.

17 Jun 2024

Diet quality in America shows modest improvement from 1999 to 2020

Poor diet continues to take a toll on American adults. It's a major risk factor for obesity, type 2 diabetes, cardiovascular disease, and certain cancers, and more than one million Americans die every year from diet-related diseases, according to the Food and Drug Administration.

17 Jun 2024

How ketone bodies contribute to brain health and memory preservation

The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice.

17 Jun 2024

Georgetown study reveals risks of oral nicotine pouches among youth

A rigorous, comprehensive synthesis of evidence from 62 studies related to the use of oral nicotine pouches by Georgetown University's Lombardi Comprehensive Cancer Center scientists and colleagues provides a much-needed assessment of how these products could lead to potential harmful consequences if used by young people.

17 Jun 2024

Exploring the advancements of Traditional Chinese Medicine to combat African Swine Fever

African Swine Fever (ASF) poses a grave threat to the swine industry, with the virus causing severe economic and agricultural disruptions since its emergence in China in 2018.

17 Jun 2024

Newly designed genetic therapy could alleviate debilitating giant moles in rare skin condition

Researchers at the Francis Crick Institute, UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital for Children (GOSH) have designed a new genetic therapy that could alleviate debilitating giant moles in a rare skin condition.

17 Jun 2024

American Heart Association launches initiative to tackle recurrent pericarditis

About 40,000 people in the United States experience recurrent pericarditis, or inflammation of the sac-like structure that protects the heart, which can cause chest pain and may lead to fluid buildup around the heart muscle.

17 Jun 2024

Stanford study identifies six depression biotypes for personalized treatment

In the not-too-distant future, a screening assessment for depression could include a quick brain scan to identify the best treatment.

17 Jun 2024

HEALing Communities Study: Data-driven intervention did not reduce opioid-related overdose death rates

A data-driven intervention that engaged communities to rapidly deploy evidence-based practices to reduce opioid-related overdose deaths – such as increasing naloxone distribution and enhancing access to medication for opioid use disorder – did not result in a statistically significant reduction in opioid-related overdose death rates during the evaluation period, according to results from the National Institutes of Health's HEALing (Helping to End Addiction Long-Term) Communities Study.

17 Jun 2024

Enterprise Therapeutics appoints Dr Renu Gupta as Chief Medical Officer and Dr Janet Hammond as Non-Executive Director

Appointments bring additional respiratory and late clinical-stage drug development experience as Company commences Phase 2a clinical trial of its lead asset.

From Enterprise Therapeutics Ltd 17 Jun 2024