Immune System News and Research

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Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular "off" switch for the inflammatory immune response that contributes to lung-constricting asthma attacks.

2 Dec 2016

New UGA research finds pathogen's motility activates immune response

Until now, a pathogen's ability to move through the body has been overlooked as a possible trigger of immune response, but new research from the University of Georgia College of Veterinary Medicine found that motility will indeed alarm the host and activate an immune response.

1 Dec 2016

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs.

1 Dec 2016

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells.

1 Dec 2016

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

1 Dec 2016

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

A new study by Lyle Hood, assistant professor of mechanical engineering at The University of Texas at San Antonio, describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments.

1 Dec 2016

Duke researchers modify popular drug-delivery technology to evade immune responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials.

1 Dec 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

Scientists synthesize antitumor compound to combat chemoresistant cancer

A team of scientists from N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences, N. K. Kol'tsov Institute of Developmental Biology of the RAS, and Immune Pharmaceuticals LLC led by MIPT's Prof. Alexander Kiselyov has synthesized an antitumor compound that could be used to fight chemoresistant cancer.

30 Nov 2016

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients.

30 Nov 2016

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function.

30 Nov 2016

Study highlights need to increase handwashing compliance among child care workers

Child care personnel properly clean their hands less than a quarter of the times they are supposed to, according to a study published in the December issue of the American Journal of Infection Control, the official journal of the Association for Professionals in Infection Control and Epidemiology.

29 Nov 2016

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania.

29 Nov 2016

MGH researchers develop new methods for mapping and measuring solid stress in tumors

Massachusetts General Hospital investigators have developed new methods for mapping and measuring solid stress - the force exerted by solid and elastic components - within tumors, an accomplishment that may lead to improved understanding of those forces and their consequences and to novel treatment strategies.

29 Nov 2016

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

The immunoproteasome dismantles proteins and the resulting fragments are displayed on the surface of cells. This helps the immune system to recognize abnormal cells. However, in chronic inflammations and autoimmune diseases this “information channel” is overactive.

29 Nov 2016

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology.

29 Nov 2016

Neuroscientists identify new regulator of immune system

Cells of the immune system can distinguish between protein molecules that are "self" and "non-self". For example, if we are exposed to pathogens such as bacteria or viruses that carry foreign molecules on their surface, the body reacts with an immune response.

28 Nov 2016

Research provides insight into molecular mechanisms involved in immune response to HBV

The innate immune system in mammals defends against infection from viruses and other microbial infections.

28 Nov 2016

NIH-supported first HIV vaccine efficacy study begins in South Africa

The first HIV vaccine efficacy study to launch anywhere in seven years is now testing whether an experimental vaccine regimen safely prevents HIV infection among South African adults.

28 Nov 2016

Social status affects immune regulation and health status in rhesus monkeys

The richest and poorest Americans differ in life expectancy by more than a decade. Glaring health inequalities across the socioeconomic spectrum are often attributed to access to medical care and differences in habits such as smoking, exercise and diet.

24 Nov 2016

Immune System News and Research

Reseachers identify cellular ‘off’ switch for inflammatory immune response in asthma attacks

New UGA research finds pathogen's motility activates immune response

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Study suggests new approach to treat white blood cells of sepsis patients

New device could revolutionize drug delivery to treat cancer and other diseases, study shows

Duke researchers modify popular drug-delivery technology to evade immune responses

Type 2 diabetes drug may someday help combat breast and ovarian cancers

Scientists synthesize antitumor compound to combat chemoresistant cancer

TGen and City of Hope collaborate to accelerate precision medicine research

Scientists identify cell-surface receptor for progranulin

Study highlights need to increase handwashing compliance among child care workers

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

MGH researchers develop new methods for mapping and measuring solid stress in tumors

TUM scientists uncover molecular mechanisms of inhibitors that can selectively thwart immunoproteasome

Early life history and genetics may play crucial role in shaping gut microbiome

Neuroscientists identify new regulator of immune system

Research provides insight into molecular mechanisms involved in immune response to HBV

NIH-supported first HIV vaccine efficacy study begins in South Africa

Social status affects immune regulation and health status in rhesus monkeys

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