Liver News and Research

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The good and bad side of anti-cancer compounds

Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells.

11 Apr 2008

Protein sulfatase 2 a possible treatment target for liver cancer recurrence and survival

Deadly and difficult to treat, liver cancer has long resisted attempts by researchers to develop ways to prolong life and prevent recurrence.

11 Apr 2008

Prevention of osteoporosis might lie in vitamin D levels

Sixty-year-old Darlene Yates has had two hip replacements, a knee replacement and this past year shattered her left femur while she was walking in her neighborhood.

10 Apr 2008

Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

Scientists at the Toronto General Hospital Research Institute have discovered a novel signaling pathway between three organs - the gut, the brain, and the liver - which lowers blood sugar when activated.

10 Apr 2008

Conjugated linoleic acid side effects - hormone leptin helps protect

An oil made of natural fatty acids that is sometimes used as a weight-loss supplement may need to be paired with hormones or other substances to prevent health problems that can follow rapid weight loss, a new study suggests.

10 Apr 2008

Low birth weight and heart problems

Researchers who have followed 5,840 people from before birth to the age of 31 have found evidence suggesting that small size at birth and excessive weight gain during adolescence and young adulthood may lead to low grade inflammation, which, in turn, is associated with an increased risk of developing heart disease.

10 Apr 2008

Hepatitis B virus triggers cell 'suicide' in patients with chronic infection

Scientists from UCL (University College London) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so - that a group of cells important in controlling the disease are triggered to 'commit suicide' in patients who are chronically infected.

9 Apr 2008

Researchers battle against dangerous corn toxin

The spiraling use of corn for food and fuel is creating heightened concerns about contamination of this staple crop with deadly aflatoxin.

9 Apr 2008

Combination therapy improves survival time for patients with more advanced liver cancer

Combining a type of chemotherapy with radiothermal therapy resulted in longer survival time for patients with advanced liver cancer, compared to receiving the therapies alone, according to a study in the April 9 issue of JAMA, the Journal of the American Medical Association.

9 Apr 2008

Scientists block early step in metastasis of prostate cancer cells

Recent studies have suggested an association between chronic inflammation and cancers of the prostate, colon, stomach and liver.

9 Apr 2008

Potential new therapy for myeloproliferative disorders

A unique partnership between industry and academia has led to human clinical trials of a new drug for a rare class of blood diseases called myeloproliferative disorders (MPD), which are all driven by the same genetic mutation and can evolve into leukemia.

8 Apr 2008

Tart cherries cut heart/diabetes risk factors

Tart cherries - frequently sold dried, frozen or in juice - may have more than just good taste and bright red color going for them, according to new animal research from the University of Michigan Cardiovascular Center.

7 Apr 2008

Stem cell breakthrough offers diabetes hope

Scientists have discovered a new technique for turning embryonic stem cells into insulin-producing pancreatic tissue in what could prove a significant breakthrough in the quest to find new treatments for diabetes.

From The University of Manchester 4 Apr 2008

Proteolix's Carfilzomib granted orphan drug designation

Proteolix, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to carfilzomib, a selective blocker of proteasome activity for the treatment of multiple myeloma.

3 Apr 2008

Feta cheese helps combat food poisoning

Eating Feta cheese made from raw milk in small seaside tavernas when you are on holiday in Greece could be a good way to combat food poisoning, according to researchers speaking today (Thursday 3 April 2008) at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

3 Apr 2008

Newly identified gene may prompt pancreas cells to form

Before a pancreas is a pancreas, it?s part of the endoderm, one of three layers of cells in a developing embryo that eventually form its organs.

2 Apr 2008

Patient interventions with low-income and minorities increases colonoscopy rates

Patient interventions are necessary to achieve higher rates of colorectal cancer screening in low-income and minority patients, according to two studies in the current issue of Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

2 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

Study shows lifetime effects of pediatric liver transplants

Parents of pediatric liver transplant recipients report lower health-related quality of life for their children two years after the surgery, compared to reports from the parents of healthy children.

28 Mar 2008

Anticancer siRNA therapy advances, thanks to nanoparticles

Small pieces of nucleic acid, known as siRNAs (short interfering RNAs), can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs in development. Indeed, at least two siRNA-based anticancer therapies, both delivered to tumors in nanoparticles, have begun human clinical trials. Now, three new reports highlight the progress that researchers are making in developing broadly applicable, nanoparticle-enabled siRNA anticancer therapeutics.

28 Mar 2008