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Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Genomic sequencing-based detection system cuts infections and saves lives

An infectious diseases detection platform developed by University of Pittsburgh scientists working with UPMC infection preventionists proved over a two-year trial that it stops outbreaks, saves lives and cuts costs.

28 Apr 2025

Computational biology uncovers RNA changes in ALS patients

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the United States are affected, and doctors still don't know what causes it.

25 Apr 2025

New RNA-based diagnostics to fight against tuberculosis

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent antibiotics can eradicate the Mycobacterium tuberculosis bacteria.

25 Apr 2025

Bacteria-based fibers offer new hope for bone healing

Have you ever wondered if there is a way to heal bones without having to take bone from another part of the body? A new doctoral thesis from the University of Borås, Sweden, now presents exciting advancements in this area. It involves using bacteria to produce fibers that can help heal bones.

25 Apr 2025

Breakthrough DNA editing in Lactobacillus offers safer probiotics

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

24 Apr 2025

New biosensor offers fast detection of H5N1 in farm air

As highly pathogenic H5N1 avian influenza continues to spread in the U.S., posing serious threats to dairy and poultry farms, both farmers and public health experts need better ways to monitor for infections, in real time, to mitigate and respond to outbreaks.

24 Apr 2025

New antibiotic offers hope for more effective Lyme disease treatment

Lyme disease, a disease transmitted when deer ticks feed on infected animals like deer and rodents, and then bite humans, impacts nearly half a million individuals in the U.S. annually.

24 Apr 2025

Mediterranean diet helps manage rheumatoid arthritis and Hashimoto’s, study shows

The Mediterranean diet shows promise in managing both systemic and organ-specific autoimmune diseases, including rheumatoid arthritis and autoimmune thyroiditis. Its anti-inflammatory and microbiota-modulating properties may reduce disease activity and improve metabolic outcomes.

23 Apr 2025

Scientists uncover why Lyme disease symptoms may linger after treatment

Symptoms that persist long after Lyme disease is treated are not uncommon - a 2022 study found that 14% of patients who were diagnosed and treated early with antibiotic therapy would still develop Post Treatment Lyme Disease (PTLD).

23 Apr 2025

Research offers new hope in the fight against antibiotic-resistant bacteria

Antibiotic resistance is a serious threat to public health. When antibiotics don't work, we risk not being able to treat many types of infections and people who would previously have been cured, can die.

23 Apr 2025

Bacterial toxin may contribute to rise in early-onset colorectal cancer

In an effort to explain a modern medical mystery, an international team of researchers led by the University of California San Diego has identified a potential microbial culprit behind the alarming rise in early-onset colorectal cancer: a bacterial toxin called colibactin.

23 Apr 2025

Scientists uncover surprising new link between gut health and blood cancer risk

Scientists at Cincinnati Children's along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk-one that could transform how we think about aging, inflammation, and the early stages of leukemia.

23 Apr 2025

AI and physicians offer distinct strengths in virtual urgent care treatment

Do physicians or artificial intelligence (AI) offer better treatment recommendations for patients examined through a virtual urgent care setting? A new Cedars-Sinai study shows physicians and AI models have distinct strengths.

23 Apr 2025

UC3M unveils three scientific research projects to combat tuberculosis

Universidad Carlos III de Madrid (UC3M) has presented three scientific research projects contributing to the fight against tuberculosis, the leading cause of death from infectious disease in the world.

23 Apr 2025

Children’s mattresses expose sleepers to hidden chemical risks, study finds

A new study tested 16 children’s mattresses and found widespread contamination with harmful semivolatile organic compounds (SVOCs) like plasticizers and flame retardants. These chemicals can migrate into the sleeping environment, increasing children's risk of allergic and neurobehavioral effects.

22 Apr 2025

Study shows how alcohol combined with burn trauma throws the intestinal microbiome into chaos

What happens in your gut after a night of heavy drinking and a severe burn injury? According to a new study, it might involve more than just pain and discomfort.

22 Apr 2025

Experimental cancer drug shows promise in boosting tuberculosis treatment

An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping infected cells die a gentler death, Johns Hopkins Medicine investigators report, based on mouse-model research of the lung-damaging disease.

21 Apr 2025

Cancer immunotherapy effective across all ages despite immune differences

Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, and the Johns Hopkins Convergence Institute.

21 Apr 2025