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Okinawa Institute of Science and Technology graduate university completes installation of new Talos Arctica Cryo-TEM from FEI

FEI has completed the installation of a new Talos Arctica™ cryo-transmission electron microscope (TEM) at the Okinawa Institute of Science and Technology Graduate University in Japan...

From Thermo Fisher Scientific – Electron Microscopy Solutions 8 Apr 2015

Two different fat grafting approaches have similar effects in reversing signs of aging skin

Two approaches to fat grafting--injection of fat cells versus fat-derived stem cells--have similar effects in reversing the cellular-level signs of aging skin, reports a study in the April issue of , the official medical journal of the

31 Mar 2015

Mutations in hair keratins increase risk for dental defects, caries

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher Olivier Duverger, National Institutes of Health-National Institute of Neurological Disorders and Stroke, Bethesda, Md., USA, will present a study titled "Hair Keratins as Structural Organic Components of Mature Enamel: The Link Between Hair Disorders and Susceptibility to Dental Caries."

20 Mar 2015

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation

13 Mar 2015

Researchers investigate effects of neuromodulatory medication on orofacial tissue

Today at the 93rd General Session and Exhibition of the International Association for Dental Research, researcher M.J. Al-Musawi, Newcastle University, Newcastle upon Tyne, UK, will present a study titled "In Vitro Effects of Topical Neuromodulatory Medication on Orofacial Tissue."

13 Mar 2015

TSRI researchers create picture of whole dynein-dynactin structure

A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.

12 Mar 2015

Andor Neo sCMOS camera is perfect partner for correlative microscopy

CD44 is recognised as an important cell surface receptor involved in the adhesion of circulating leukocytes to endothelium, a process that is critical for their trafficking in the vasculature. Now, a Japanese group of researchers using an ultra-sensitive Andor Neo sCMOS camera in their correlative microscopy set-up has demonstrated that microvilli projections around the cell surface mediate this adhesion.

From Andor Technology Ltd. 11 Mar 2015

Weak spots in ebola’s defenses: an interview with Dr. Andrew Ward

There are hundreds of other antibodies against Ebola that we are in the process of imaging using the electron microscope. We are looking for new sites of vulnerability as well as subtle differences in the way the known sites are attacked. In particular we are looking for antibodies that the virus is unlikely to escape from when it mutates.

11 Mar 2015

Nanobody Nano-85 holds promise for detection of noroviral RNA

Infection with highly contagious noroviruses, while not usually fatal, can lead to a slew of unpleasant symptoms such as excessive vomiting and diarrhea. Current treatment options are limited to rehydration of the patient. "Additionally, noroviruses come in a variety of constantly evolving strains.

9 Mar 2015

Scientists uncover how primary protein responsible for multidrug resistance reacts to therapeutic drugs

Cancer patients fear the possibility that one day their cells might start rendering many different chemotherapy regimens ineffective. This phenomenon, called multidrug resistance, leads to tumors that defy treatment.

5 Mar 2015

TSRI researchers show how ABC transporters cause multidrug resistance

3 Mar 2015

Neurodegenerative disease research using NMR: an interview with Christian Griesinger

Christian Griesinger, director of the NMR-based Structural Biology department at the Max-Planck Institute for Biophysical Chemistry, talks about his research into neurodegenerative diseases using NMR to examine the dynamics of disordered proteins.

From Bruker BioSpin - NMR, EPR and Imaging 23 Feb 2015

NTU Singapore setting up new institute to find cures for human diseases

Nanyang Technological University is setting up a new institute to advance research in the life sciences, with a focus on ramping up Singapore's efforts in finding cures for human diseases.

16 Feb 2015

Research provides new insights into rapid defence responses in human immune system

Researchers have uncovered a sieve-like structure in lymph nodes that regulates the transport of proteins and migration of white blood cells into lymph nodes.

12 Feb 2015

Discovery provides new insights into rapid defence responses in the immune system

Researchers have uncovered a sieve-like structure in lymph nodes that regulates the transport of proteins and migration of white blood cells into lymph nodes. The discovery, made by scientists working at the University of Turku, Finland, will provide new insights into rapid defence responses in the human immune system. The research was carried out with funding from the Academy of Finland and the Sigrid Juselius Foundation.

11 Feb 2015

Recipients of The 2015 Protein Society Awards announced

The Protein Society, the premiere international society dedicated to supporting protein research, announces the winners of The 2015 Protein Society Awards. The awards will be conferred at the 29th Annual Symposium of The Protein Society (July 22-25, 2015, Barcelona, Spain).

5 Feb 2015

Modelling the biological mesoscale: an interview with Professor Art Olson

The biological mesoscale range includes biological structures that range from 10 to 100 nanometers (billionths of a meter). Structures in this size range include viruses, cellular organelles, large molecular complexes, and any other internal cellular environments within that range.

18 Jan 2015

New insight into molecular mechanism of ancient evolutionary enzyme

A team led by structural biologists at The Scripps Research Institute has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme produced in most forms of life on Earth.

12 Jan 2015

Brandeis University researchers capture highest resolution images of cilia ever

Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a mutation disrupts the function or structure of cilia, the effects on the human body are devastating and sometimes lethal.

18 Dec 2014

Researchers develop nanomimics of host cell membranes that trick malaria parasites

Malaria parasites invade human red blood cells, they then disrupt them and infect others. Researchers at the University of Basel and the Swiss Tropical and Public Health Institute have now developed so-called nanomimics of host cell membranes that trick the parasites. This could lead to novel treatment and vaccination strategies in the fight against malaria and other infectious diseases.

9 Dec 2014