Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Gout treatment could potentially reduce complications accompanying metabolic syndrome

The drug colchicine, used to treat the arthritic condition gout, could potentially reduce complications accompanying metabolic syndrome, a combination of high blood pressure, high blood sugar and other conditions that increase the risk of heart disease and type 2 diabetes, according to researchers at the National Institutes of Health.

2 Apr 2019

Nanovaccine boosts immunity in mice with gut microbiome-mediated metabolic syndrome

A new class of biomaterial developed by Cornell researchers for an infectious disease nanovaccine effectively boosted immunity in mice with metabolic disorders linked to gut bacteria - a population that shows resistance to traditional flu and polio vaccines.

29 Mar 2019

Causes of diabetes decline or disappear when ‘zombie cells’ are removed, shows study

Mayo Clinic researchers and their collaborators have shown that when senescent cells -- also known as "zombie cells" -- are removed from fat tissue in obese mice, severity of diabetes and a range of its causes or consequences decline or disappear. The findings appear in Aging Cell.

26 Mar 2019

Time-restricted eating may prove to be a dietary intervention against breast cancer

Changing when you eat rather than what you eat may prove to be a dietary intervention against breast cancer, suggests a new mouse study to be presented Saturday at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Altering gut microbiome may be potential treatment option for PCOS

Symptoms of polycystic ovary syndrome improved with exposure to healthy bacteria in the gut, according to a study in a mouse model of this common women's endocrine disorder.

25 Mar 2019

High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring

A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found that a high-fat, high-sugar diet in mouse mothers before and during pregnancy causes problems in the hearts of their offspring, and that such problems are passed down at least three generations, even if the younger generations only eat a standard mouse chow diet.

22 Mar 2019

Mild sleep apnea during pregnancy changes sugar levels and may affect infant growth patterns

A study conducted by Sarah Farabi, PhD, RN, while she was a post-doctoral fellow working with Dr. Teri Hernandez at the University of Colorado College of Nursing and School of Medicine in 2018 found that mild sleep apnea changed sugar levels during pregnancy and was connected to infant growth patterns related to increased risk of obesity.

20 Mar 2019

Green tea lowers obesity, health risks in mice

Green tea cuts obesity and a number of inflammatory biomarkers linked with poor health in a new study.

14 Mar 2019

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

The search by scientists to find ways to combat obesity continues. Recently, investigators have been exploring whether they can engage the lymphatic system to help regulate obesity-induced inflammation of fat (adipose) tissue and restore systemic metabolic fitness.

14 Mar 2019

$2.7 million grant supports UIC researchers to study role of arsenic in development of diabetes

A five-year, $2.7 million grant from the National Institute of Environmental Health Sciences will help researchers at the University of Illinois at Chicago answer basic questions about the role of arsenic in the development of diabetes and examine the mechanisms by which selenoproteins – found in the human body in 25 different forms – counter the effects of arsenic.

11 Mar 2019

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin.

8 Mar 2019

Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes

Individuals who take cholesterol-lowering statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type 2 diabetes, according to an analysis published in the British Journal of Clinical Pharmacology.

6 Mar 2019

Patients experiment with prescription drugs to fight aging

Dr. Alan Green's patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

6 Mar 2019

Study elucidates mechanism behind development of steroid diabetes

Steroids are used for treating various diseases such as allergic disorders, but they occasionally cause adverse effects, such as steroid diabetes and other metabolic disturbances. Since steroids act throughout the body, how these adverse effects are caused and by which organ are not well understood.

28 Feb 2019

Study shows benefits of including red raspberries in the diet of people with pre-diabetes

A study released today from the Illinois Institute of Technology shows the benefits of including red raspberries in the diet of individuals with pre-diabetes and insulin resistance.

26 Feb 2019

Study investigates the role of estrogen in controlling glucose homeostasis

The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus.

13 Feb 2019

Researchers link protein clusterin to many facets of cardiometabolic syndrome risk

During a study spanning nearly a decade, researchers at The Ohio State University College of Medicine, Houston Methodist Research Institute and Houston Methodist Cancer Center have linked the protein clusterin - for the first time -- to many different facets of cardiometabolic syndrome risk through its actions in the liver.

4 Feb 2019

Children's air pollution exposure at school could be linked to higher overweight, obesity risk

Exposure to air pollution, particularly at school, could be associated with a higher risk of overweight and obesity during childhood.

31 Jan 2019

Positive personality traits may help to reduce risk of developing type 2 diabetes

It has been said that a good personality can help one succeed in life. But can it also guard against disease risk? A new study based on data from the Women's Health Initiative shows that positive personality traits, such as optimism, actually may help to reduce the risk of developing type 2 diabetes.

24 Jan 2019

Fiderstat could be used as chemopreventative drug for intestinal cancers caused by APC gene mutations

Colorectal Cancer has now become one of the leading causes of death. Studies indicate that smoking, low physical activities and high-fat diet are a major risk factor for colorectal cancer.

21 Jan 2019