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ACMG issues guidance for reporting uncertain genetic test variants

The American College of Medical Genetics and Genomics (ACMG) has published a new statement, Points to Consider for the Reporting of Variants of Uncertain Significance in Germline Genetic and Genomic Testing, providing guidance to laboratories and healthcare professionals on the reporting and communication of variants of uncertain significance (VUS) identified through genetic and genomic testing.

1 Jul 2026

New safety strategies reduced serious surgical events in children

Ann & Robert H. Lurie Children's Hospital of Chicago achieved more than a 13-fold improvement in surgical safety after implementing a series of interventions based on high reliability principles across its operating rooms.

1 Jul 2026

Study potential new therapeutic strategy for patients with ATRX-mutant gliomas

A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of the most common genetic alterations in glioma rewires the cancer cell genome to fuel tumor progression, suggesting a potential new therapeutic strategy for patients with ATRX-mutant gliomas.

1 Jul 2026

Blood pressure and cholesterol gaps shrink among older adults with obesity

Over the last three decades, differences in unhealthy cholesterol levels and blood pressure between older adults with obesity and those with a normal Body Mass Index (BMI) have narrowed or disappeared in several high-income countries, suggests a study published in The Lancet.

1 Jul 2026

Engineered CAR T cells show promise against myeloproliferative neoplasms

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, in new research led by UCL and University of Oxford researchers.

1 Jul 2026

Imaging scans detect prostate cancer progression despite stable PSA levels

Patients with advanced prostate cancer may need periodic imaging scans to catch tumor growth even with stable levels of prostate-specific antigen (PSA), a protein in the blood that doctors routinely monitor for cancer progression, according to an analysis led by researchers at Weill Cornell Medicine and Duke University.

1 Jul 2026

Opioid prescribing after pediatric surgery varies widely across hospitals

Whether children receive an opioid prescription after surgery varies substantially by procedure type and hospital, according to a new national analysis published in the Journal of the American College of Surgeons (JACS).

1 Jul 2026

Depression-like behavior may accelerate endocrine aging in primates

A new review was published in Volume 18 of Aging on June 11, 2026, titled "Age-related dysfunctions of the neuroendocrine axes in nonhuman primates with depression-like and anxious behavior."

1 Jul 2026

Scientists urge caution over psychedelics as ADHD treatment

In recent years, there has been growing interest among adults with ADHD in the practice of microdosing classic psychedelics such as psilocybin and LSD.

1 Jul 2026

AI speeds development of therapeutic hydrogels for gum disease

Periodontitis is one of the most common chronic inflammatory diseases worldwide and a leading cause of tooth loss in adults.

1 Jul 2026

Collaboration shapes the future of personalized medicine innovation

The development of personalized medicine depends on collaboration between multiple stakeholders, who must navigate uncertainty while shaping expectations of future value.

1 Jul 2026

Reversing macrophage metabolism may improve cancer immunotherapy outcomes

Tumor-associated macrophages (TAMs) are among the most abundant immune cells in the tumor microenvironment.

1 Jul 2026

LEF1 and niche-derived factors regulate T cell stemness across chronic diseases

T cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops.

1 Jul 2026

UC San Diego study reveals genetic causes of rare neuromuscular disorders

Scientists at the University of California San Diego have uncovered how genetic mutations cause a rare group of inherited neuromuscular disorders and identified promising new strategies to correct them, including a potential new use for an existing antidepressant.

1 Jul 2026

German study identifies therapeutic Achilles' heel for advanced colorectal cancer

A team led by researchers from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute has discovered a promising new approach to treating advanced colorectal cancer.

1 Jul 2026

Biological heart valves support safer pregnancies despite reoperation risks

In severe disease of the aortic valve, choosing a new heart valve is especially difficult for young women who want to become pregnant.

1 Jul 2026

Advanced imaging technology unlocks exosome potential for disease diagnosis

Tiny particles released by most human cells may be promising targets for diagnosis and treatment of an array of diseases from cancer to Alzheimer's, but scientists have struggled to see them and study them in detail.

1 Jul 2026

Prenatal paracetamol use does not increase child neurodevelopmental risks

Researchers from the University of Hong Kong (HKUMed), along with Aston Pharmacy School's Professor Ian Chi-Kei Wong, have shown that using paracetamol (acetaminophen) during pregnancy does not increase a child's risk of developing autism spectrum disorder (ASD) or attention‑deficit hyperactivity disorder (ADHD).

1 Jul 2026