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Study brings hope for a more personalized approach to treat ER+ breast cancer

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

28 Aug 2025

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Traumatic injuries of the central nervous system (CNS)-such as traumatic brain injury (TBI) and traumatic spinal cord injury (SCI)-are characterized by oxidative damage and neuroinflammation.

28 Aug 2025

Chronic neuron overactivation may drive Parkinson's disease progression

Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die.

28 Aug 2025

Gut mast cells produce key molecules driving food allergy anaphylaxis

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause difficulty breathing, a dangerous drop in blood pressure and even death.

28 Aug 2025

Aptamer Group introduces novel biomarker discovery service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

27 Aug 2025

Increasing numbers of bariatric surgery patients turn to GLP-1 drugs

Bariatric surgery is usually effective on its own for weight loss, but an increasing proportion of patients who undergo bariatric surgery start taking one of the new glucagon-like 1 peptide receptor agonist (GLP-1) weight-loss drugs in the years after their surgery, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

27 Aug 2025

CURE GABA-A and Grann Pharmaceuticals announce global partnership to advance rare neurological therapies

CURE GABA-A (https://curegabaa.org/) is proud to announce a major new partnership with Grann Pharmaceuticals. CURE GABA-A is a nonprofit patient advocacy group founded by Monica Joanna Elnekaveh, mother to Eleanor Elnekaveh.

27 Aug 2025

GLP-1 receptor agonists improve heart failure outcomes and reduce environmental impact

New research has found that the use of GLP-1 receptor agonists, a class of medications commonly prescribed for patients with obesity and diabetes, reduces the environmental footprint of healthcare and clinical outcomes when used to treat heart failure.

27 Aug 2025

Targeting gut signaling protein may protect against alcohol-related liver damage

Alcohol-associated liver disease (ALD) is a major cause of liver transplantation and death worldwide, and its impact is only growing. In 2022, the annual cost of ALD in the United States was $31 billion.

27 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

People with lower interleukin-6 activity have a reduced risk of cardiovascular diseases, a new LMU study reveals.

26 Aug 2025

Fat location, not BMI, drives heart ageing risk in men and women

Researchers using UK Biobank imaging data found that where fat is stored in the body, not just how much, determines cardiovascular ageing. Visceral, liver, and muscle fat accelerate ageing, while gynoid fat protects women before menopause.

25 Aug 2025

New study reveals long road to seizure control for people with focal epilepsy

Antiseizure medications help the majority of people with focal epilepsy, a common form of the neurological disorder.

25 Aug 2025

New molecular mechanism offers hope for treating depression in the elderly

Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified.

25 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs).

22 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

Computational framework deciphers cellular organization

One of the most fundamental processes in all of biology is the spontaneous organization of cells into clusters that divide and eventually turn into shapes – be they organs, wings, or limbs.

22 Aug 2025

Hypothalamic neurons help maintain blood sugar during daily activities

The brain controls the release of glucose in a wide range of stressful circumstances, including fasting and low blood sugar levels.

21 Aug 2025

Receptor News and Research

Study brings hope for a more personalized approach to treat ER+ breast cancer

Researchers develop novel exosome-based therapeutic agent for treating traumatic CNS injuries

Chronic neuron overactivation may drive Parkinson's disease progression

Gut mast cells produce key molecules driving food allergy anaphylaxis

Aptamer Group introduces novel biomarker discovery service

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

Increasing numbers of bariatric surgery patients turn to GLP-1 drugs

CURE GABA-A and Grann Pharmaceuticals announce global partnership to advance rare neurological therapies

GLP-1 receptor agonists improve heart failure outcomes and reduce environmental impact

Targeting gut signaling protein may protect against alcohol-related liver damage

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

Fat location, not BMI, drives heart ageing risk in men and women

New study reveals long road to seizure control for people with focal epilepsy

New molecular mechanism offers hope for treating depression in the elderly

SOX2 drives progression and therapy resistance in advanced prostate cancer

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

Computational framework deciphers cellular organization

Hypothalamic neurons help maintain blood sugar during daily activities

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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