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Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Penn Medicine and Children's Hospital of Philadelphia, who together pioneered the research and development of the world's first personalized cellular therapy for cancer - also known as CAR T cell therapy - have announced plans with Costa Rica's CCSS, or the Caja Costarricense de Seguro Social (Social Security Program), to facilitate CAR T research in Costa Rica.

23 May 2022

Study: Liver transplants from drug overdose donors increased in the pandemic's first year

Liver transplants from drug overdose donors rose significantly in the pandemic's first year, helping keep the number of liver transplants in the U.S. stable despite COVID-19 disruptions, according to a study to be presented at Digestive Disease Week 2022.

23 May 2022

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Researchers assessed the efficacy of COVID-19 vaccines in immunocompromised adults.

23 May 2022

Liver acuity circle allocation policy associated with procurement delays

A national policy change to facilitate the broader sharing of donor livers through "acuity circles" has resulted in procurement delays, according to a researcher at the University of Miami Miller School of Medicine.

20 May 2022

Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

A step-by-step plan to create a digital twin of the human immune system

An article published May 20 in Nature Digital Medicine provides a step-by-step plan for an international effort to create a digital twin of the human immune system.

20 May 2022

Islet cell transplant program offers an effective treatment for patients with hard-to-control Type 1 diabetes

After 20 years of perfecting their technique, the team behind the largest islet cell transplant program in the world reports the procedure is a safe, reliable and life-changing treatment for people with hard-to-control diabetes.

19 May 2022

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

In a recent study posted to the medRxiv* preprint server, researchers estimated the humoral immunity imparted by the two/three doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in solid organ transplant recipients (SOTRs).

18 May 2022

Researchers explore COVID-19 vaccination in immunocompromised individuals

A new study discusses the safety and efficacy of the COVID-19 vaccination and potential strategies to optimize protection in patients with impaired immunity.

17 May 2022

Novel approach allows islet transplants to survive and control diabetes

In type 1 diabetes, an autoimmune response attacks the pancreas's insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but replacing lost beta cells through transplants of islets, a group of cells in the pancreas, represents an attractive option.

13 May 2022

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

In a new study, a team of researchers from the University of Missouri, Georgia Tech and Harvard University has demonstrated the successful use of a novel Type 1 diabetes treatment in a large animal model.

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

For the first time, researchers have successfully used bacteriophages – viruses that kill bacteria – to treat an antibiotic-resistant mycobacterial lung infection, clearing the way for a young National Jewish Health patient with cystic fibrosis to receive a life-saving lung transplant.

13 May 2022

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Researchers at The University of Texas MD Anderson Cancer Center have discovered that adolescent and young adult (AYA) cancer survivors of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) have reduced long-term survival rates compared to their peers without cancer.

13 May 2022

Lean people with NAFLD more likely to have cardiovascular disease than those who are overweight

Those with a normal body mass index (BMI) with non-alcoholic fatty liver disease (NAFLD) are more likely to have cardiovascular disease than those who are overweight or living with obesity, according to research selected for presentation at Digestive Disease Week 2022.

13 May 2022

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Researchers evaluated the immune responses after the third and fourth doses of homologous and heterologous mRNA vaccines against COVID-19 in kidney transplant recipients.

4 May 2022

Transplant News and Research

Penn Medicine and CHOP announce plans with Costa Rica's CCSS for CAR T research

Study: Liver transplants from drug overdose donors increased in the pandemic's first year

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Liver acuity circle allocation policy associated with procurement delays

Study outlines risk factors for autoimmune hepatitis after liver transplant

A step-by-step plan to create a digital twin of the human immune system

Islet cell transplant program offers an effective treatment for patients with hard-to-control Type 1 diabetes

Immunity conferred by COVID-19 vaccines in solid organ transplant recipients

Researchers explore COVID-19 vaccination in immunocompromised individuals

Novel approach allows islet transplants to survive and control diabetes

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

Adolescent and young adult leukemia survivors have reduced long-term survival compared to peers without cancer

Lean people with NAFLD more likely to have cardiovascular disease than those who are overweight

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

Study shows efficacy of COVID-19 vaccine in people receiving cancer treatment

Fecal microbiota transplant can reverse hallmarks of aging in mice

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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