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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Key mechanisms for delivery of LNP-encapsulated siRNAs to the liver

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the publication of pre-clinical research in the journal Molecular Therapy revealing key mechanisms related to the systemic delivery of RNAi therapeutics using lipid nanoparticles (LNPs).

12 May 2010

Giardia's surface proteins may work as vaccines to help prevent infections: Research scholar

The intestinal parasite Giardia lamblia changes outfits nearly as often as a fashion model on a Parisian runway. With more than 200 protein coats in its molecular wardrobe, this troublesome creature-the cause of innumerable cases of diarrheal infections each year-can change its appearance from one instant to the next, throwing the body's immune cells off track.

12 May 2010

Researchers develop new method for tracing carbon flux

Microbial communities are performing important functions all around us - from the earth in our flowerpots to the human gut. Now researchers have developed a method for studying the metabolic functions of microbial communities in detail.

12 May 2010

Compugen discovers CGEN-928 as antibody drug target for treatment of multiple myeloma

Compugen Ltd. announced today the discovery and initial experimental validation of CGEN-928 as a drug target for the treatment of multiple myeloma. In recently completed studies, CGEN-928, a membrane protein which previously had no known function or potential clinical utility, demonstrated broad expression in human multiple myeloma tumor cells, including drug resistant and aggressive primary tumor cell lines.

12 May 2010

Preliminary data from Achillion Pharmaceuticals' Phase 1b clinical trial of ACH-1625 reported

Achillion Pharmaceuticals, Inc. today reported additional preliminary data from its Phase 1b clinical trial of ACH-1625, which demonstrated that both the third and fourth patient cohorts receiving treatment with ACH-1625 achieved meaningful reductions in HCV RNA after five-day monotherapy, with continued safety and tolerability in patients with hepatitis C.

12 May 2010

Rosetta Genomics announces USPTO notice of allowance for Sanger hsa-miR-451

Rosetta Genomics, Ltd., a leading developer and provider of microRNA-based molecular diagnostic tests, announced today the receipt of a new notice of allowance from the United States Patent and Trademark Office ("USPTO") for U.S. patent application 11/418,870, including claims related to Sanger hsa-miR-451. miR-451 is used in the Company's miRview™ mets test, which accurately identifies the primary tumor site in patients with metastatic cancer and Cancer of Unknown Primary (CUP).

11 May 2010

SNP biomarker could reduce guesswork associated with prescribing drugs

A tiny gene mutation in human liver cells could one day influence how high or low a dose patients need of about half of the clinically used drugs on the market, new research suggests.

11 May 2010

FDA grants EUA for IQuum's Liat Influenza A/2009 H1N1 Assay

IQuum, Inc. today announced it has been granted an Emergency Use Authorization (EUA) from the U.S. Food and Drug Administration (FDA) for its Liat™ Influenza A/2009 H1N1 Assay. The assay detects and differentiates 2009 H1N1 influenza viral RNA starting from collected nasopharyngeal swab samples in less than 30 minutes.

10 May 2010

UT Southwestern researchers uncover core function of gene involved in Fragile X syndrome

Researchers at UT Southwestern Medical Center have discovered how the genetic mutation that causes Fragile X syndrome, the most common form of inherited mental retardation, interferes with the "pruning" of nerve connections in the brain. Their findings appear in the April 29 issue of Neuron.

10 May 2010

Peptides: A new clue on the origins of life

Emory University scientists have discovered that simple peptides can organize into bi-layer membranes. The finding suggests a "missing link" between the pre-biotic Earth's chemical inventory and the organizational scaffolding essential to life.

7 May 2010

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Quark Pharmaceuticals, Inc., the world leader in clinical development of RNAi-based therapeutics, announced today that researchers from Pfizer, Inc. presented data on in vivo activity of PF-04523655 at the Association for Research in Vision and Ophthalmology (ARVO) annual meeting, being held May 2-6, 2010 in Fort Lauderdale.

7 May 2010

Series Three of Percepta's Gene Expression Profiling Life Science Dashboard market research report

Percepta Associates Inc. announces the release of Series Three of its Gene Expression Profiling Life Science Dashboard market research report. Unique to the Percepta report, Series Three offers comparisons to the findings of Series One (February 2007) and Series Two (April 2008).

6 May 2010

Scientists analyze genetic networks of microRNAs in tumors

Genes interact in complex networks that govern cellular processes, much like people connect a social network through relationships. Researchers are now discovering how biological networks change and are rewired in cancer.

6 May 2010

Multistage nanovector system for siRNA delivery lengthens therapeutic effects of ovarian cancer treatment

New research by scientists at The University of Texas Health Science Center at Houston (UTHealth) and The University of Texas M. D. Anderson Cancer Center could make it easier for patients to use a family of promising experimental cancer therapeutics known as small interfering RNA (siRNA).

6 May 2010

Latest LLMDA technology available to detect viruses, bacteria

Law enforcement authorities seeking to detect bioterrorism attacks, doctors diagnosing diseases and regulatory agencies checking product safety may find a new ally in a Lawrence Livermore National Laboratory detection technology.

6 May 2010

Genomic Health reports 22% revenue growth, 58% decrease in net loss for first-quarter 2010

Genomic Health, Inc. today reported financial results and business progress for the quarter ended March 31, 2010.

6 May 2010

Alnylam Pharmaceuticals reports consolidated financial results for first quarter 2010

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today reported its consolidated financial results for the first quarter ended March 31, 2010, and company highlights.

6 May 2010

NIH awards CSU biochemists $7.8M grant to study gene regulation within cells

A team of top biochemists at Colorado State University will investigate how chromosomes untangle to expose genes that dictate cell behavior - a unique project that could have a significant impact on understanding human health.

5 May 2010

BioDiscovery signs OEM Agreement with Exiqon

BioDiscovery, Inc., a leader in integrated software solutions for microarray-based research, and Exiqon A/S, a leader in microRNA analysis products and services, announced today an OEM Agreement incorporating BioDiscovery's array analysis and visualization software with Exiqon's arrays.

5 May 2010

Medication used to treat heart arrhythmias also reduces myotonic dystrophy: Researchers

A medication most often used to treat heart arrhythmias also reduces a central symptom of myotonic dystrophy, the most common type of muscular dystrophy in adults.

5 May 2010

RNA News and Research

Further Reading

Key mechanisms for delivery of LNP-encapsulated siRNAs to the liver

Giardia's surface proteins may work as vaccines to help prevent infections: Research scholar

Researchers develop new method for tracing carbon flux

Compugen discovers CGEN-928 as antibody drug target for treatment of multiple myeloma

Preliminary data from Achillion Pharmaceuticals' Phase 1b clinical trial of ACH-1625 reported

Rosetta Genomics announces USPTO notice of allowance for Sanger hsa-miR-451

SNP biomarker could reduce guesswork associated with prescribing drugs

FDA grants EUA for IQuum's Liat Influenza A/2009 H1N1 Assay

UT Southwestern researchers uncover core function of gene involved in Fragile X syndrome

Peptides: A new clue on the origins of life

Pfizer presents data on in vivo activity of PF-04523655 siRNA drug candidate at ARVO annual meeting

Series Three of Percepta's Gene Expression Profiling Life Science Dashboard market research report

Scientists analyze genetic networks of microRNAs in tumors

Multistage nanovector system for siRNA delivery lengthens therapeutic effects of ovarian cancer treatment

Latest LLMDA technology available to detect viruses, bacteria

Genomic Health reports 22% revenue growth, 58% decrease in net loss for first-quarter 2010

Alnylam Pharmaceuticals reports consolidated financial results for first quarter 2010

NIH awards CSU biochemists $7.8M grant to study gene regulation within cells

BioDiscovery signs OEM Agreement with Exiqon

Medication used to treat heart arrhythmias also reduces myotonic dystrophy: Researchers

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