Liver News and Research

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Protein deficiency leads to faster fat burning in mice, study shows

Researchers have developed a new, lean mouse with characteristics suggesting that someday, using medication to manipulate a specific protein in humans could emerge as a strategy to treat obesity and disorders associated with excess weight, such as diabetes and metabolic syndrome.

13 Mar 2008

Obesity bottlenecks cellular power plant

The machinery responsible for energy production in fat cells is working poorly as a result of obesity.

13 Mar 2008

Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

12 Mar 2008

Combined therapeutic approach of stenting and photodynamic therapy improves survival in late stage liver cancer patients

A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology , the official journal of the American Gastroenterological Association (AGA) Institute.

12 Mar 2008

Weight-loss more effective than intensive insulin therapy for type 2 diabetics, according to expert

11 Mar 2008

New surgery technique for pancreatic cancer offers hope to sufferers

Just days after it was announced in the media that Hollywood actor Patrick Swayze was being treated for pancreatic cancer, doctors in Britain have performed a new operation for people with the advanced stage of the disease.

11 Mar 2008

A glass of wine a day protects middle-aged teetotallers from heart disease

Scientists say that middle-aged 'teetotallers' can quickly reduce their risk of heart disease by having a daily tipple.

10 Mar 2008

Folic acid consumption before and during pregnancy

Taking a folic acid pill a day — a simple measure to prevent severe birth defects — is under-promoted in the media, under-recommended by health care providers and underused by women of childbearing age, according to a new review of studies.

6 Mar 2008

Chemotherapy with chemoradiation for pancreatic cancer has small survival benefit

The addition of the drug gemcitabine with chemoradiation for the treatment of patients who had surgery for pancreatic cancer was associated with a survival benefit, although this improvement was not statistically significant, according to a study in the March 5 issue of JAMA.

6 Mar 2008

Rimonabant weight-loss drug might fight alcoholic fatty liver

The cannabinoid receptors best known for delivering the psychological effects of marijuana also explain the connection between chronic alcohol use and a buildup of fat in the liver, according to a report in the March issue of Cell Metabolism, a publication of Cell Press.

6 Mar 2008

Arsenic aids tumor imaging when joined to cancer-homing drug

Arsenic linked to a drug that binds to the blood vessels of cancerous tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancer's response to therapy, researchers at UT Southwestern Medical Center have found.

6 Mar 2008

Combination therapy of Prostacyclin, Sildenafil and Bosentan may treat portopulmonary hypertension

Combination therapy of Prostacyclin, Sildenafil, and Bosentan helped a young male patient with severe portopulmonary hypertension improve enough to receive a liver transplant.

6 Mar 2008

Serum fibrosis markers correlate with liver fibrosis stage in patients with advanced chronic hep C

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

4 Mar 2008

Elevated liver enzymes associated with higher future mortality

A new population-based epidemiological study has found that elevated liver enzymes discovered during routine medical care are associated with higher future mortality.

4 Mar 2008

New nanotube findings give boost to potential biomedical applications

Carbon nanotubes have shown real promise as highly accurate vehicles for delivering antitumor agents into malignant cells, but a dearth of data about what happens to the tubes after they discharge their medical payloads has been a major stumbling block to progress.

3 Mar 2008

Nanotechnology advances brain cancer detection and therapy

Brain cancer is one of the most aggressive and lethal of malignancies, made even more difficult to treat by the fact that most anticancer drugs have a hard time even getting to the tumors.

3 Mar 2008

Clinical trial shows reduction in mortality for children with severe Langerhans cell histiocytosis

A new international study finds that introducing an increased intensity of chemotherapy in children with severe Langerhans cell histiocytosis (LCH) can reduce the mortality rate for this disorder by as much as 20 percent when the patient demonstrates a rapid response to such treatment.

3 Mar 2008

Arsenic used to label antibodies for the detection of tumors

3 Mar 2008

Using microorganisms to remove trichloroethene from water

In 2002, Bruce Rittmann, PhD, director of the Biodesign Institute's Center for Environmental Biotechnology, received a patent for an innovative way to use nature to lend society a hand.

28 Feb 2008