Immune System News and Research

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SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist and cancer researcher Robert L. Harrod has been awarded a $436,500 grant from the National Cancer Institute to further his lab's research into how certain viruses cause cancers in humans.

8 Nov 2016

Weight loss condition provides clues to why cancer immunotherapy may fail in many patients

A weight loss condition that affects patients with cancer has provided clues as to why cancer immunotherapy - a new approach to treating cancer by boosting a patient's immune system -- may fail in a substantial number of patients.

8 Nov 2016

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

One of the worst cruelties of lethal cancer is the phenomenon called wasting, or in medical terms, cachexia (pronounced ka-CHEX-ia), in which a patient seems literally to diminish in bodily terms as the cancer ravages one or more internal organs.

8 Nov 2016

Caltech researchers develop new technique that increases safety of TCR gene therapy

The human body produces T cells to recognize and fight disease. Each T cell has a unique T cell receptor (or TCR) on its surface that surveils small fragments of proteins presented by other cells.

8 Nov 2016

Researchers develop new strategy to immunize against microbes that cause foodborne illness

University of California, Irvine and MIT researchers have developed a new strategy to immunize against microbes that invade the gastrointestinal tract, including Salmonella, which causes more foodborne illness in the United States than any other bacteria.

8 Nov 2016

Scientists develop new strategy to stop uncontrollable poison ivy itch

Scientists at Duke Health and Zhejiang Chinese Medical University have developed a strategy to stop the uncontrollable itch caused by urushiol, the oily sap common to poison ivy, poison sumac, poison oak and even mango trees.

7 Nov 2016

Scientists turn iron-scavenging power against common UTI-causing bacteria

For most invading bacteria, the bladder is not a friendly place. But for those that have figured out how to scavenge iron from their hosts, it's a fine place to grow and reproduce.

7 Nov 2016

Clinical study to test safety and ability of investigational Zika vaccine candidate begins

The first of five early stage clinical trials to test the safety and ability of an investigational Zika vaccine candidate called the Zika Purified Inactivated Virus (ZPIV) vaccine to generate an immune system response has begun at the Walter Reed Army Institute of Research Clinical Trial Center in Silver Spring, Maryland.

7 Nov 2016

Biologic drugs may help prevent progressive bone loss in patients with RA

A new review by the International Osteoporosis Foundation Chronic Inflammation and Bone Structure Working Group concludes that early and aggressive treatment of Rheumatoid Arthritis (RA) with biologic drugs, specifically biological disease-modifying anti-rheumatic drugs (DMARDs), may be most effective in halting progressive bone loss in patients with RA.

7 Nov 2016

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study.

7 Nov 2016

Researchers discover set of immune proteins that facilitate long-lasting immunity against malaria

Houston Methodist researchers have discovered a set of immune proteins that facilitate long-lasting immunity against malaria.

7 Nov 2016

Researchers test new drug that shows promise to prevent pre-term birth

Researchers from the University of Adelaide have successfully tested a drug that is showing some early promise in efforts to prevent pre-term birth.

7 Nov 2016

Vitamin D deficiency may increase risk of developing bladder cancer

Vitamin D deficiency is associated with an increased risk of developing bladder cancer, according to a systematic review of seven studies presented today at the Society for Endocrinology annual conference in Brighton.

7 Nov 2016

Scientists unravel viral molecular strategies to counter mammalian immune system

As mammals evolve, so do mammalian viruses. In doing so, they develop creative and effective ways to counter and evade the antiviral responses of their mammal hosts' immune systems.

7 Nov 2016

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events.

7 Nov 2016

Vaccine-related rubella virus causes harm in some patients with primary immunodeficiency disorders

Some patients with rare primary immunodeficiency disorders may be at risk for infection by rubella virus, and possibly serious skin inflammation, after receiving the rubella vaccine, usually administered as part of the measles-mumps-rubella (MMR) vaccine.

7 Nov 2016

Age, genetic disposition play important role in susceptibility to Lyme disease

People react very differently to an infection with the Borrelia bacterium that causes Lyme disease.

7 Nov 2016

Gut microbiome may help improve immunotherapy response in melanoma patients

Patients with malignant melanoma - whose disease has spread - are more likely to respond to immunotherapy treatment if they had greater diversity in their gut bacteria, according to new research presented at the National Cancer Research Institute's Cancer Conference in Liverpool.

6 Nov 2016

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

5 Nov 2016

TB bacteria can be divided into generalists and specialists, study finds

Tuberculosis (TB) is a major global public health problem. Treatment often takes many months and till this day there is no effective vaccine. Various TB bacterial strains exist globally, with different geographical spread. Only the so-called Lineage 4 occurs on all continents.

4 Nov 2016

Immune System News and Research

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

Weight loss condition provides clues to why cancer immunotherapy may fail in many patients

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

Caltech researchers develop new technique that increases safety of TCR gene therapy

Researchers develop new strategy to immunize against microbes that cause foodborne illness

Scientists develop new strategy to stop uncontrollable poison ivy itch

Scientists turn iron-scavenging power against common UTI-causing bacteria

Clinical study to test safety and ability of investigational Zika vaccine candidate begins

Biologic drugs may help prevent progressive bone loss in patients with RA

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Researchers discover set of immune proteins that facilitate long-lasting immunity against malaria

Researchers test new drug that shows promise to prevent pre-term birth

Vitamin D deficiency may increase risk of developing bladder cancer

Scientists unravel viral molecular strategies to counter mammalian immune system

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

Vaccine-related rubella virus causes harm in some patients with primary immunodeficiency disorders

Age, genetic disposition play important role in susceptibility to Lyme disease

Gut microbiome may help improve immunotherapy response in melanoma patients

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

TB bacteria can be divided into generalists and specialists, study finds

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