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Leptin gene therapy aids weight loss without significant side effect of bone loss

Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State University and University of Florida.

22 Oct 2015

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Dietary fatty acids affect the development and progression of autoimmune chronic-inflammatory diseases such as multiple sclerosis. In a collaborative study between the Departments of Neurology at the Ruhr-Universität Bochum (St. Josef-Hospital) and the Friedrich Alexander Universtiy Erlangen, researchers now found that long-chain fatty acids promote the development and propagation of CNS reactive immune cells in the intestinal wall. On the contrary, short-chain fatty acids promote the development and propagation of regulatory cells in the immune system.

22 Oct 2015

Study reveals poor levels of use, availability and affordability of cardiovascular disease medicines worldwide

New research published in The Lancet shows that the use of vital life-saving generic (and supposedly inexpensive) medicines for prevention in people with existing heart disease is poor worldwide. In low-income and middle-income countries these medicines are not widely available and, when available, can often be unaffordable. In rich countries, although such medicines are both available and affordable, 35% to 50% of patients who have heart disease or a previous stroke still do not receive them.

22 Oct 2015

New test may help predict spread of breast cancer to the brain

Women with particularly aggressive forms of breast cancer could be identified by a test that predicts whether the disease is likely to spread to the brain.

22 Oct 2015

NHS Trusts not compliant with safer sharps rules two years after regulation enacted, says new MindMetre reseach

New research from independent research organization MindMetre has revealed that many NHS Trusts are not complying with ‘safer sharps’ rules, putting NHS employees at unnecessary risk of ‘needlestick’ injuries and possible blood-borne infections such as hepatitis and HIV.

22 Oct 2015

Children who receive repeated antibiotics gain weight faster over time

Kids who receive antibiotics throughout the course of their childhoods gain weight significantly faster than those who do not, according to new Johns Hopkins Bloomberg School of Public Health research.

22 Oct 2015

New study from TSRI and Salk points to cause of debilitating nerve disease

Scientists at The Scripps Research Institute (TSRI) and the Salk Institute for Biological Studies have discovered how a mutant protein triggers nerve damage in a subtype of Charcot-Marie-Tooth (CMT) diseases, a group of currently untreatable conditions that cause loss of function in a person’s hands and feet.

22 Oct 2015

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

Scientists have developed a new technique for looking at the initial steps of DNA oxidation – a process which can lead to DNA damage, mutations and cancers. The breakthrough, which uses DNA in crystals, should help related research in the fields of cancer medicine and drug development.

22 Oct 2015

Novel method provides greater means to study protein changes in Alzheimer's disease

Using 10-year-old archival brain tissue from patients with Alzheimer's disease, a research team from NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level--providing greater means to study protein changes found in Alzheimer's disease.

22 Oct 2015

Radical shift required in use of heart medicine worldwide

Many people in the world who need essential heart medicine do not get it, even in rich countries, says new research published today in the medical journal The Lancet.

22 Oct 2015

Restoring memory in aging mice

A new study, led by scientists at The Scripps Research Institute (TSRI), the Veterans Affairs San Diego Healthcare System (VA) and University of California (UC) San Diego School of Medicine shows that increasing a crucial cholesterol-binding membrane protein in nerve cells (neurons) within the brain can improve learning and memory in aged mice.

22 Oct 2015

Researchers examine effectiveness of interventions to improve quality of drinking water for preventing diarrhoea

Researchers from Emory University, the London School of Hygiene and Tropical Medicine, and the World Health Organization have carried out an updated Cochrane review to assess the effectiveness of interventions to improve water quality for preventing diarrhoea.

22 Oct 2015

Study: Number of postdocs in biological and biomedical sciences on the decline in U.S.

After more than 30 years of steady growth, the number of postdocs in the biological and biomedical sciences is on the decline in the United States, according to a new paper in The FASEB Journal.

22 Oct 2015

High-resolution X-ray method can predict risk of re-operation in patients who receive new hip prosthesis

Between 5 and 30 percent of those who receive a new hip prosthesis will require a re-operation during their lifetime. New research shows that a high-resolution X-ray method can predict which patients have the greatest risk of re-operation.

22 Oct 2015

Gait analysis could lead to reduced falls, injuries in people with glaucoma

Washington State University researchers have developed a way to carefully analyze a person's gait with sensors, an innovation that could lead to reduced falls and injuries in people with glaucoma, the second leading cause of blindness in the United States.

22 Oct 2015

Veltassa (patiromer for oral suspension) gets FDA approval for treatment of hyperkalemia

The U.S. Food and Drug Administration today approved Veltassa (patiromer for oral suspension) to treat hyperkalemia, a serious condition in which the amount of potassium in the blood is too high.

22 Oct 2015

NIMR core imaging facility chooses Prior Scientific’s linear motor stage

Prior Scientific has announced that the Core Imaging Facility at the UK's prestigious National Institute for Medical Research (NIMR) has chosen a Prior HLD117 linear motor stage to be the sample platform at the center of a new system based around an Olympus IX83 microscope.

From Prior Scientific Instruments Ltd. 21 Oct 2015

New generation of RNAscope products for RNA-biomarker analysis in FFPE tissue released

Advanced Cell Diagnostics Inc. (ACD), the market leader in tissue-based RNA analysis tools for molecular pathology, has announced the release of its next version RNAscope® in situ hybridization (ISH) assay – RNAscope 2.5.

From Advanced Cell Diagnostics 21 Oct 2015

MetaVision SafeTrack chosen by University Hospital Southampton for electronic observations

iMDsoft announced that University Hospital Southampton NHS Foundation Trust (UHS) in the UK chose MetaVision SafeTrack™, iMDsoft's new mobile electronic observation solution, for all 1237 of its general ward level 1 beds. This agreement follows the hospital's choice of the MetaVision® Patient Data Management System (PDMS) for all of their high acuity environments.

21 Oct 2015

Confocal microscope designed specifically for scientists launched by Caliber ID

Caliber Imaging & Diagnostics, Inc. (Caliber I.D.), an Andover, MA-based medical technologies company with more than 20 years of experience in the design and development of innovative imaging solutions for the examination of tissue at the cellular level, has introduced its first confocal microscope exclusively for the research scientist, the RS-G4.

21 Oct 2015

Research News and Research

Leptin gene therapy aids weight loss without significant side effect of bone loss

Study shows how dietary fatty acids affect development and progression of multiple sclerosis

Study reveals poor levels of use, availability and affordability of cardiovascular disease medicines worldwide

New test may help predict spread of breast cancer to the brain

NHS Trusts not compliant with safer sharps rules two years after regulation enacted, says new MindMetre reseach

Children who receive repeated antibiotics gain weight faster over time

New study from TSRI and Salk points to cause of debilitating nerve disease

Ground-breaking discovery helps scientists view DNA damage with crystal clarity

Novel method provides greater means to study protein changes in Alzheimer's disease

Radical shift required in use of heart medicine worldwide

Restoring memory in aging mice

Researchers examine effectiveness of interventions to improve quality of drinking water for preventing diarrhoea

Study: Number of postdocs in biological and biomedical sciences on the decline in U.S.

High-resolution X-ray method can predict risk of re-operation in patients who receive new hip prosthesis

Gait analysis could lead to reduced falls, injuries in people with glaucoma

Veltassa (patiromer for oral suspension) gets FDA approval for treatment of hyperkalemia

NIMR core imaging facility chooses Prior Scientific’s linear motor stage

New generation of RNAscope products for RNA-biomarker analysis in FFPE tissue released

MetaVision SafeTrack chosen by University Hospital Southampton for electronic observations

Confocal microscope designed specifically for scientists launched by Caliber ID

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