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Researchers pinpoint spike protein regions as targets for passive and active COVID-19 vaccines

Researchers at Stanford University School of Medicine have identified regions of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that have relatively few mutations and might therefore serve as important targets for prophylactic agents against coronavirus disease 2019 (COVID-19).

10 Jan 2021

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Patients with tuberous sclerosis complex, a genetic disorder characterized by the growth of noncancerous tumors in multiple organs of the body, have limited treatment options.

8 Jan 2021

Researchers unravel the process that makes viruses infectious

Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus 'package up' their genetic code, allowing them to infect cells.

8 Jan 2021

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests, and that false negative results can occur with any molecular test for the detection of SARS-CoV-2 if a mutation occurs in the part of the virus's genome assessed by that test.

8 Jan 2021

Researchers create first usable computational model of entire SARS-COV-2 virus

Researchers at the University of Chicago have created the first usable computational model of the entire virus responsible for COVID-19 - and they are making this model widely available to help advance research during the pandemic.

8 Jan 2021

New approach to tame botulinum toxin for drug delivery

While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known.

8 Jan 2021

Scientists gain new insight into how the immune system can be better used to destroy cancer cells

Scientists at the University of Southampton's Centre for Cancer Immunology have gained new insight into how the immune system can be better used to find and kill cancer cells.

8 Jan 2021

Patients taking immunosuppressive drugs did not have worse COVID-19 outcomes

People taking immunosuppressive drugs to prevent organ transplant rejection or to treat inflammatory or autoimmune diseases do not fare worse than others on average when they are hospitalized with COVID-19, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

7 Jan 2021

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Now, an intriguing recent study appeared on the bioRxiv * preprint server describes the use of in vitro evolution to elicit affinity maturation of the viral receptor-binding domain (RBD) of the spike protein to bind the host cell angiotensin-converting enzyme 2 (ACE2) with greater affinity.

7 Jan 2021

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center published promising findings today in the New England Journal of Medicine on preventing a common complication to lifesaving blood stem cell transplantation in leukemia.

7 Jan 2021

Mount Sinai launches new center for psychedelics research

The Icahn School of Medicine at Mount Sinai has launched a new center for psychedelics research.

7 Jan 2021

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

SNSF Sinergia grant awarded to research groups in Switzerland and Norway to identify novel treatment strategies for children with aggressive brain tumors.

7 Jan 2021

Study explores women's interest in long-acting injectable antiretroviral therapy

A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection--including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs.

7 Jan 2021

Engineered nanodroplets and ultrasound 'drill' can help eliminate tough blood clots

Engineering researchers have developed a new technique for eliminating particularly tough blood clots, using engineered nanodroplets and an ultrasound "drill" to break up the clots from the inside out.

7 Jan 2021

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Researchers at the Icahn School of Medicine at Mount Sinai have identified three major molecular subtypes of Alzheimer's disease (AD) using data from RNA sequencing.

7 Jan 2021

Study finds associations between functional seizures and psychiatric disorders, stroke

In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

7 Jan 2021

Researchers provide comprehensive molecular characterization of head and neck cancers

In what is believed to be the most comprehensive molecular characterization to date of the most common type of head and neck cancer, researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.

7 Jan 2021

KHN’s ‘What the Health?’: Georgia turns the Senate blue

Surprise Democratic victories in Georgia's two runoff elections this week will give Democrats control of the Senate, which means they will be in charge of both houses of Congress and the White House for the first time since 2010.

7 Jan 2021

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

Researchers at Yale University School of Medicine found that SARS-CoV-2 viral loads in saliva are higher for patients with associated risk factors and underlying conditions that lead to severe COVID-19 and death. Thus, saliva viral loads could be used to predict disease severity.

7 Jan 2021

San Francisco wrestles with drug approach as death and chaos engulf Tenderloin

In early 2019, Tom Wolf posted a thank-you on Twitter to the cop who had arrested him the previous spring, when he was homeless and strung out in a doorway with 103 tiny bindles of heroin and cocaine in a plastic baggie at his feet.

7 Jan 2021

Drugs News and Research

Researchers pinpoint spike protein regions as targets for passive and active COVID-19 vaccines

Gene therapy can effectively treat mice with tuberous sclerosis complex, shows study

Researchers unravel the process that makes viruses infectious

FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

Researchers create first usable computational model of entire SARS-COV-2 virus

New approach to tame botulinum toxin for drug delivery

Scientists gain new insight into how the immune system can be better used to destroy cancer cells

Patients taking immunosuppressive drugs did not have worse COVID-19 outcomes

High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

IU research findings could prevent common complication of blood stem cell transplantation in leukemia

Mount Sinai launches new center for psychedelics research

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

Study explores women's interest in long-acting injectable antiretroviral therapy

Engineered nanodroplets and ultrasound 'drill' can help eliminate tough blood clots

RNA sequencing data reveals three major molecular subtypes of Alzheimer's disease

Study finds associations between functional seizures and psychiatric disorders, stroke

Researchers provide comprehensive molecular characterization of head and neck cancers

KHN’s ‘What the Health?’: Georgia turns the Senate blue

SARS-CoV-2 viral load in saliva may be linked to COVID-19 disease severity

San Francisco wrestles with drug approach as death and chaos engulf Tenderloin

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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