Immune System News and Research

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Calcium triggers virulence switch from acute to chronic lung infections

The bacterium Pseudomonas aeruginosa is a life-threatening pathogen in hospitals. About ten percent of all nosocomial infections, in particular pneumonia, are caused by this pathogen.

24 Oct 2016

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation, including arthritis, asthma, cancer, diabetes, heart disease and even mental illness.

24 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

Study provides potential new target to combat cytomegalovirus infections

Viruses hijack the molecular machinery in human cells to survive and replicate, often damaging those host cells in the process.

24 Oct 2016

TSRI scientists discover reason for lack of successful HCV vaccine design

Researchers have been trying for decades to develop a vaccine against the globally endemic hepatitis C virus (HCV). Now scientists at The Scripps Research Institute have discovered one reason why success has so far been elusive.

24 Oct 2016

Identification of new lung cancer subtypes could lead to personalized immunotherapies

Personalized therapies can potentially improve the outcomes of patients with lung cancer, but how to best design such an approach is not always clear.

24 Oct 2016

Novel approach could help counter Influenza A virus in immune-compromised patients

To infect its victims, influenza A heads for the lungs, where it latches onto sialic acid on the surface of cells.

24 Oct 2016

Adult brain cells may be vulnerable to Zika infection, new study suggests

Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for Allergy and Immunology suggests that certain adult brain cells may be vulnerable to infection as well.

24 Oct 2016

Tackling antimicrobial resistance by turning ideas into action

“This is our moment to tackle antimicrobial resistance (AMR),” declared Ed Whiting, Head of Policy and Chief of Staff, Wellcome Trust, London at Antibiotic Research UK’s inaugural lecture held at Portcullis House, Westminster today. Ed’s pragmatic discussion mirrored the theme of the event: turning ideas in action.

24 Oct 2016

Scientists identify genetic cause and biological mechanisms linked to new human immunodeficiency

A multi-institutional, international team of scientists has discovered the genetic cause and biological mechanisms linked to a new human immunodeficiency. The study, which is published in Nature Immunology, also identifies a potential treatment.

24 Oct 2016

New disgnostic tool could help doctors make more informed prescriptions

Students from the University of Sheffield are building a device capable of quickly diagnosing bacterial infections, which could help doctors improve the way they prescribe treatment for patients.

24 Oct 2016

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Tumor cells collected during the removal of a cancerous bladder and - in some cases - transplanted into mice with weakened immune systems, could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care for patients with this common cancer, according to a study published online on Oct. 24, 2016, in Scientific Reports.

24 Oct 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

Health benefit labelling may help people eat recommended amount of vegetables, research suggests

Most Australians do not meet World Health Organisation standards for vegetable consumption and now research points to a lack of understanding about the nutritional benefits of the humble vegetable, with health benefit labelling potentially providing the answer.

24 Oct 2016

ERAS programs help patients better prepare for surgery and recover faster, studies reveal

Enhanced recovery after surgery (ERAS) programs, an important component of the Perioperative Surgical Home (PSH), are helping patients better prepare for surgery and recuperate faster afterward, according to two new studies being presented at the ANESTHESIOLOGY 2016 annual meeting.

24 Oct 2016

Sanford opens new immunotherapy study on colorectal cancer

Sanford Health has opened another clinical trial exploring the power of the body's immune system to fight cancer.

21 Oct 2016

Monash researchers provide key insight into how T cells recognize viruses

Last week marked the 20th anniversary of Professors Doherty and Zinkernagel's Nobel Prize in Medicine for discoveries concerning the immune system.

21 Oct 2016

Novel approach may speed up development of new drugs against skin disease

In an ideal world, the newest and most effective drugs for chronic inflammatory conditions would immediately help everyone who took them.

21 Oct 2016

Scientists discover new mechanism for inadequate immune defense against chronic viral infection

Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development. They have been published in the journal "Science Immunology".

21 Oct 2016

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

While successful treatment of HIV with antiretroviral medications leads to undetectable levels of virus in the blood, controls the disease and leads to much longer lifespans, scientists know that HIV continues to reside in tissues.

21 Oct 2016

Immune System News and Research

Calcium triggers virulence switch from acute to chronic lung infections

Researchers elucidate molecular mechanisms underlying negative effects of early-life stress

New approach could overcome large immunosuppressive tumors

Study provides potential new target to combat cytomegalovirus infections

TSRI scientists discover reason for lack of successful HCV vaccine design

Identification of new lung cancer subtypes could lead to personalized immunotherapies

Novel approach could help counter Influenza A virus in immune-compromised patients

Adult brain cells may be vulnerable to Zika infection, new study suggests

Tackling antimicrobial resistance by turning ideas into action

Scientists identify genetic cause and biological mechanisms linked to new human immunodeficiency

New disgnostic tool could help doctors make more informed prescriptions

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Health benefit labelling may help people eat recommended amount of vegetables, research suggests

ERAS programs help patients better prepare for surgery and recover faster, studies reveal

Sanford opens new immunotherapy study on colorectal cancer

Monash researchers provide key insight into how T cells recognize viruses

Novel approach may speed up development of new drugs against skin disease

Scientists discover new mechanism for inadequate immune defense against chronic viral infection

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

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