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Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

New data presented at the 2016 San Antonio Breast Cancer Symposium (SABCS) demonstrate that analyzing tumor biology with the Oncotype DX test can identify patients unlikely to benefit from chemotherapy prior to breast cancer surgery (neoadjuvant setting) and guide treatment decisions without compromising outcomes.

22 Dec 2016

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Clinical Genomics, a private company developing evidence-based diagnostic tools for colorectal cancer, today announced the launch of Colvera, a blood-based test for colorectal cancer (CRC) recurrence monitoring. Colvera is the result of a decade of research, development and clinical validation in more than 4,000 patients.

22 Dec 2016

Increase in double mastectomy is “striking,” says study

Almost half of patients with early stage breast cancer considered double mastectomy and one in six went ahead, including many who were only at a low risk of developing another breast cancer, according to a new study.

22 Dec 2016

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Researchers at the Icahn School of Medicine at Mount Sinai are working on the basic science that lays the groundwork to finding a way to treat and prevent the Zika virus, a global health risk.

22 Dec 2016

Survey finds substantial use of CPM procedure among women with unilateral breast cancer

In a survey of women who underwent treatment for early-stage breast cancer in one breast, contralateral prophylactic mastectomy use was substantial among patients without clinical indications but was low when patients reported that their surgeon recommended against it, according to a study published online by JAMA Surgery.

22 Dec 2016

Study shows effectiveness of pelvic floor muscle training for prevention of prolapse symptoms

Researchers, including several University of Otago academics, have conducted the first trial of pelvic floor muscle training for the prevention of prolapse symptoms in women with early signs of prolapse several years after childbirth, publishing their findings in the world's leading medical journal The Lancet.

21 Dec 2016

Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

Nearly three years of research have brought about remarkable results for the majority of 80 patients subjected to targeted alpha therapy of metastatic prostate cancer.

21 Dec 2016

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

A new way to fight multidrug-resistant bacteria by blinding them rather than killing them proved highly effective in a model of burn injuries, UT Southwestern Medical Center research shows.

21 Dec 2016

Clinical study tests adult stem cell therapy for infants with congenital HLHS

In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

21 Dec 2016

Hormone receptor could be potential biomarker for gastric cancer, research shows

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, the Veterans Affairs Medical Center in Miami, and Shantou University Medical College in China, have shown that the hormone receptor GHRH-R could be a potential biomarker for gastric cancer, enabling earlier diagnoses and better staging.

21 Dec 2016

Scientists develop 'LevelCheck' algorithm to help identify, label vertebrae during spine surgery

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering have developed a way to automatically label images of individual vertebrae during spine surgery, preventing mistakes and saving surgeons both time and stress in the operating room.

20 Dec 2016

‘Local’ learning health system can improve clinical quality while reducing costs

Providing high-quality patient care while reducing costs is a significant goal in the current health care reform environment.

20 Dec 2016

A positive announcement for DePuy Synthes’ ATTUNE® Knee System

DePuy Synthes, part of the Johnson & Johnson Family of Companies, today announced that implant survivorship data from the 2016 Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) confirm positive early results for DePuy Synthes’ ATTUNE® Knee System. These data add to recent UK Joint Registry evidence which indicate that survivorship for the ATTUNE Knee compares favorably to other cemented knee systems in its class. In addition, recently-presented interim data on two studies suggest improved patient reported outcomes measures with the ATTUNE Knee compared to other leading knee systems.

20 Dec 2016

How can we tackle antimicrobial resistance?

Antimicrobial resistance happens when bugs, like bacteria, fungi or viruses, change, or evolve, when they’re exposed to drugs, like antibiotics, antifungals, or antivirals. Bugs that develop antimicrobial resistance are sometimes referred to as ‘superbugs’.

20 Dec 2016

New X-ray imaging technology holds potential for life-saving uses in security and healthcare

An exciting X-ray imaging technology has been successfully developed to the point where it is now ready for translation into all kinds of beneficial applications, including potentially life-saving uses in security and healthcare.

20 Dec 2016

Novel genomics model allows personalized approach to radiation therapy

Cancer therapeutics is currently in the era of precision medicine - personalized medicine for individual patients based on their tumor biology.

20 Dec 2016

New graphene system can detect activity levels of interfaced normal and cancer cells

What can't graphene do? You can scratch "detect cancer" off of that list. By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis.

20 Dec 2016

Regular NSAID use linked to increased risk of endometrial cancer mortality

Regular use of over-the-counter non-steroidal inflammatory drugs such as aspirin and ibuprofen is associated with an increased risk of dying in patients diagnosed with Type 1 endometrial cancers, according to a new population-based study led by The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

20 Dec 2016

University of Limerick professor outlines evidence for categorising mesentery as organ

A University of Limerick professor has identified an emerging area of science having reclassified part of the digestive system as an organ.

20 Dec 2016

$New review explores approaches for prevention of hip fracture in very high risk patients$

New review explores approaches for prevention of hip fracture in very high risk patients

Hip fractures are of great concern as they are the most severe type of fracture in osteoporotic patients, associated with premature death, and commonly leading to long-term physical disability, impaired capacity to perform daily activities and live independently, and reduced quality of life.

20 Dec 2016

Surgery News and Research

Oncotype DX test can help guide treatment decisions and enable personalized care before breast cancer surgery

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Increase in double mastectomy is “striking,” says study

Mount Sinai researchers laying groundwork to find effective treatment for Zika virus

Survey finds substantial use of CPM procedure among women with unilateral breast cancer

Study shows effectiveness of pelvic floor muscle training for prevention of prolapse symptoms

Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

Clinical study tests adult stem cell therapy for infants with congenital HLHS

Hormone receptor could be potential biomarker for gastric cancer, research shows

Scientists develop 'LevelCheck' algorithm to help identify, label vertebrae during spine surgery

‘Local’ learning health system can improve clinical quality while reducing costs

A positive announcement for DePuy Synthes’ ATTUNE® Knee System

How can we tackle antimicrobial resistance?

New X-ray imaging technology holds potential for life-saving uses in security and healthcare

Novel genomics model allows personalized approach to radiation therapy

New graphene system can detect activity levels of interfaced normal and cancer cells

Regular NSAID use linked to increased risk of endometrial cancer mortality

University of Limerick professor outlines evidence for categorising mesentery as organ

New review explores approaches for prevention of hip fracture in very high risk patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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