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New method clarifies whether NOTCH1 variants cause congenital heart defects

One to two out of every 100 newborn babies are born with a Congenital Heart Defect (CHD), yet the exact cause remains unclear.

26 Feb 2026

Combining stem cell therapy with fetal surgery shows promise for treating myelomeningocele

A phase 1 clinical trial published in The Lancet has shown that combining stem cell therapy with standard fetal surgery before birth is a safe and promising approach to treat myelomeningocele, a severe form of spina bifida.

26 Feb 2026

Organ donation after circulatory death expands transplant opportunities

Organ donation after the heart stops beating, a practice called donation after circulatory death, has gone from rare to routine in the United States, a new study shows.

26 Feb 2026

‘You aren’t trapped’: Hundreds of US nurses choose Canada over Trump’s America

Last month, Justin and Amy Miller packed their vehicles with three kids, two dogs, a pet bearded dragon, and whatever belongings they could fit, then drove 2,000 miles from Wisconsin to British Columbia to leave President Donald Trump’s America.

26 Feb 2026

Reducing miRNA levels helps rescue vascular defects in Rett syndrome

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood vessels, making them leaky.

25 Feb 2026

Vitamin B3 shows promise for treating rare genetic disorder

Scientists at Gladstone Institutes have flipped the traditional approach to finding potential treatments for deadly diseases.

25 Feb 2026

RSV and COVID-19 trigger different immune responses in infants

Young infants hospitalized with respiratory syncytial virus (RSV) often become much sicker compared to those infected with SARS-CoV-2, the virus that causes COVID-19.

25 Feb 2026

Ketogenic diet alters brain signaling to reduce epileptic seizures

A ketogenic diet - one that is high in fat and extremely low in carbohydrates - has been known for decades to reduce seizures in some epilepsy patients.

25 Feb 2026

Disrupted lymphatic vessels may drive chronic organ transplant rejection

Despite advances in the field of organ transplantation, long-term organ rejection that can become apparent a decade or more after a heart or lung transplant remains a common problem for patients.

25 Feb 2026

COVID-19 initially reduced asthma attacks but widened socioeconomic disparities, study finds

A large retrospective study of more than 162,000 asthma patients in the Bronx found that asthma exacerbations dropped sharply after the onset of COVID-19 before rebounding in children but remaining lower in adults. Socioeconomic disparities widened during the pandemic, particularly among Medicaid recipients, certain income groups, and patients with documented unmet social needs, while racial and ethnic gaps persisted without significantly expanding.

25 Feb 2026

Having “hasslers” in your network linked to faster aging and poorer health

Researchers analyzed a state-representative US sample to examine whether negative social ties, termed “hasslers,” are associated with epigenetic age acceleration and faster biological aging. Each additional hassler was linked to roughly nine months higher biological age and a 1.5% faster pace of aging, with particularly strong associations for mental health outcomes.

25 Feb 2026

Early-life immune system differences drive childhood eczema risk

A team of researchers at the Icahn School of Medicine at Mount Sinai, Weill Cornell Medicine, and other institutions have uncovered a key biological explanation for why eczema so often starts in childhood.

25 Feb 2026

Breakthrough gene therapy for sickle cell disease remains out of reach in Africa

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most patients in Africa.

25 Feb 2026

Opioids offer limited short-term relief for acute pain

The world's largest review of opioid pain relievers prescribed for acute pain found these medicines provide only small, short-term relief for some acute conditions and are ineffective for some others.

25 Feb 2026

Democrats decry meager medical care for detainees in funding fight

Fernando Viera Reyes needed a biopsy for possible prostate cancer when the Trump administration sent him to an immigration detention center in California's Mojave Desert.

25 Feb 2026

New global guidelines improve reporting of pediatric randomized controlled trials

Researchers at The Hospital for Sick Children (SickKids), working with international collaborators and youth and family caregivers, have developed a child- and youth-centred global standard for reporting paediatric randomized controlled trials (RCTs) protocols and final reports.

24 Feb 2026

Untreated sleep apnea may cost the UK and US billions annually

Untreated obstructive sleep apnea may be costing the UK and US economies billions of pounds/dollars in lost productivity every year, with a considerable proportion of working age adults experiencing symptoms indicative of the breathing disorder, suggests an analysis published online in the journal Thorax.

24 Feb 2026