Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Research group aims to offer more personalized treatments for pediatric cancers

A new Emmy Noether Independent Junior Research Group at Charité - Universitätsmedizin Berlin is studying the development of pediatric cancers. The research group is being funded by the German Research Foundation (DFG) and will receive €1.7 million over five years.

31 Aug 2018

Subcutaneous injection of new protein helps treat hemophilia more effectively

Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also happen into any tissue in the body including the muscles, brain, or eyes.

31 Aug 2018

Pfizer terminates clinical studies evaluating domagrozumab for treatment of Duchenne muscular dystrophy

Pfizer Inc. announced today that it is terminating two ongoing clinical studies evaluating domagrozumab (PF-06252616) for the treatment of Duchenne muscular dystrophy (DMD): a Phase 2 safety and efficacy study (B5161002) and an open-label extension study (B5161004).

30 Aug 2018

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration accepted its supplemental Biologics License Application for Sprycel (dasatinib) in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia.

30 Aug 2018

Study suggests new strategies for using cell metabolism to treat cancer

Researchers at the University of Cincinnati College of Medicine have discovered that cell metabolism plays an important role in the ability of cells to start a survival program called autophagy, an unwanted side effect of some anti-cancer drugs that helps some tumor cells dodge treatment and eventually regrow into new tumors.

29 Aug 2018

International research effort yields 'Image-Activated Cell Sorting' technology

Invented over 50 years ago, flow cytometry-based cell sorting has become a widely used tool in biology labs for physically isolating cells based on their global surface marker expression profiles.

28 Aug 2018

NorthShore University HealthSystem highlights utility of Streck ARM-D Kits for antimicrobial resistance detection

Streck, Inc., received great interest for Streck ARM-D Kits, used in the detection of antibiotic resistance, at ASM Microbe 2018 in Atlanta.

28 Aug 2018

Researchers reveal an unlikely protector against growth of metastatic breast cancer

At the time of initial diagnosis, most patients with breast cancer show no signs that their cancer has spread elsewhere in the body. Yet, up to 30 percent of patients will ultimately experience metastasis, with breast cancer taking root and growing at other sites in the body, sometimes months, years or even decades later.

27 Aug 2018

Scientists work towards solving mystery of incurable blood diseases

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes, which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia.

23 Aug 2018

Researchers identify genes responsible for inherited breast cancer in Nigerian women

For the first time, DNA contributed by Sub-Saharan African women has been thoroughly evaluated with innovative genomics technology in an effort to understand the genetic bases for breast cancer in African populations.

22 Aug 2018

Researchers find STAT3 as therapeutic target for chronic active EBV infection

Tokyo Medical and Dental University study shows that ruxolitinib-induced inhibition of STAT3 activity blocks survival and reduces pro-inflammatory cytokine production in Epstein-Barr virus (EBV)-infected clonally proliferating T- or NK-cells in Chronic active Epstein-Barr virus infection.

20 Aug 2018

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

The Departments of Emergency Medicine and Hematology at the Icahn School of Medicine at Mount Sinai have been awarded a $4 million grant from the National Institutes of Health toward further study of inhaled corticosteroids to treat sickle cell disease in individuals who do not have asthma.

14 Aug 2018

Patients with chronic lymphocytic leukemia have higher risk of melanoma, shows study

While studying a large group of individuals with chronic lymphocytic leukemia, a Wilmot Cancer Institute scientific team made an important discovery -- these patients had a sizable 600 percent higher risk of melanoma, the most dangerous form of skin cancer.

10 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Cleveland Clinic awarded $4.7 million grant to study prevention of cancer-associated blood clots

The National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

European Commission approves Pfizer’s first oncology biosimilar

Pfizer Inc. today announced the European Commission has approved TRAZIMERA, a biosimilar to Herceptin (trastuzumab), for the treatment of human epidermal growth factor overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.

31 Jul 2018

MedTest Dx reveal two new clinical analyzers

MedTest Dx recently announced the introduction of its BA-800M Clinical Analyzer and BC-5390 5-Part Differential Hematology Analyzer.

31 Jul 2018

FDA approves first therapy for patients with rare tumors of the adrenal gland

The U.S. Food and Drug Administration today approved Azedra (iobenguane I 131) injection for intravenous use for the treatment of adults and adolescents age 12 and older with rare tumors of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumor site and require systemic anticancer therapy.

31 Jul 2018

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended broadening the existing marketing authorization for Darzalex® for use as frontline therapy.

28 Jul 2018

Hematology News and Research

Further Reading

Research group aims to offer more personalized treatments for pediatric cancers

Subcutaneous injection of new protein helps treat hemophilia more effectively

Pfizer terminates clinical studies evaluating domagrozumab for treatment of Duchenne muscular dystrophy

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Study suggests new strategies for using cell metabolism to treat cancer

International research effort yields 'Image-Activated Cell Sorting' technology

NorthShore University HealthSystem highlights utility of Streck ARM-D Kits for antimicrobial resistance detection

Researchers reveal an unlikely protector against growth of metastatic breast cancer

Scientists work towards solving mystery of incurable blood diseases

Researchers identify genes responsible for inherited breast cancer in Nigerian women

Researchers find STAT3 as therapeutic target for chronic active EBV infection

NIH grant for Mount Sinai to study use of inhaled corticosteroids for treatment of sickle cell disease

Patients with chronic lymphocytic leukemia have higher risk of melanoma, shows study

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

Cleveland Clinic awarded $4.7 million grant to study prevention of cancer-associated blood clots

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

European Commission approves Pfizer’s first oncology biosimilar

MedTest Dx reveal two new clinical analyzers

FDA approves first therapy for patients with rare tumors of the adrenal gland

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

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