Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Fragmented care does not impact survival in rare sarcoma cases

Fragmented care - receiving medical treatment at more than one facility - has been associated with both positive and negative outcomes for cancer patients depending on a number of factors such as cancer type and treatment venue.

13 May 2025

DiffInvex identifies key genes driving chemotherapy resistance

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

13 May 2025

New treatment approach boosts survival rates for patients with aggressive, inherited breast cancers

A new treatment approach significantly improves survival rates for patients with aggressive, inherited breast cancers, according to Cambridge researchers.

13 May 2025

‘Cell line atlas’ can help better understand biliary tract cancer biology

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a rare and aggressive group of cancers, carrying one of the worst prognoses in all of oncology.

12 May 2025

Review spotlights MYC as a multidimensional therapeutic target in cancer

A new review in Genes and Diseases explores the central role of MYC, a master regulatory protein, in the development and progression of cancer, spotlighting its potential as a multidimensional therapeutic target.

12 May 2025

HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Blood-based biomarkers predict therapy failure in prostate cancer patients

New research has identified specific blood-based biomarkers that can predict the failure of prostate cancer treatment in both hormone-sensitive and castration-resistant patients.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

Multimodal AI system improves lung cancer screening accuracy

Lung cancer is one of the most challenging diseases, making early diagnosis crucial for effective treatment.

11 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

FDA approves at home HPV test as alternative to pap smear

The Food and Drug Administration just approved an at home test that could be an optional alternative to a yearly pap smear. The test looks for human papilloma virus, or HPV, which causes nearly all incidences of cervical cancer.

11 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Redlining continues to impact breast cancer survival in America

In neighborhoods across America, women face a daunting threat from a federal practice that, although it was outlawed decades ago, continues to negatively impact their health today.

10 May 2025

Ovary and fallopian tube removal linked to lower death risk in BRCA carriers with breast cancer

Women diagnosed with breast cancer who carry particular BRCA1 and BRCA2 genetic variants are offered surgery to remove the ovaries and fallopian tubes as this dramatically reduces their risk of ovarian cancer.

8 May 2025

Next-generation "armored" CAR T cell therapy shows promising results in lymphoma patients

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including commercially available CAR T cell therapies.

8 May 2025

Researchers trace origins of aggressive childhood brain tumors

Medulloblastoma is one of the most common malignant tumors of the central nervous system (CNS) in children and adolescents. It develops in the area of the cerebellum, which is responsible for movement coordination, among other things.

7 May 2025

New consensus on clear aligner treatment aims to improve orthodontic outcomes

Malocclusion affects nearly half of the global population, impacting oral function and aesthetics. Clear aligners have gained popularity due to their discreet appearance and ease of use, but their effectiveness varies depending on the type of tooth movement required.

7 May 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025