Proliferation News and Research

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How do fingerprints develop?

A fingerprint is both complex and unique, and that is why it has fascinated scientists for so long. New research reveals the details relating to their formation and how their characteristic variability is achieved during embryonic development.

15 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

Scientists find a good treatment target for pulmonary hypertension

The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood inside our lungs and oxygen to our bodies.

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

Evolutionary convergence of the SARS-CoV-2 A-lineage spike sequences

Researchers assessed the impact of evolutionary convergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) A-lineage (Clade 19B) spike sequences on B-lineage viral replication.

9 Mar 2023

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type.

8 Mar 2023

Newly identified bone matrix protein may help treat osteosarcoma

A study published in the Journal of Orthopaedic Research has identified a bone matrix protein called Secreted phosphoprotein 24 kD (Spp24) that may help to treat osteosarcoma, the most common type of bone cancer.

8 Mar 2023

Intermittent fasting's impact on bone health

Although several studies have indicated intermittent fasting (IF) promotes weight loss and improves metabolic health, its effect on bone health is unclear. Recently, scientists reviewed existing literature and summarized the effect of varied forms of IF, such as the 5:2 diet, alternate day fasting (ADF), and time-restricted eating/feeding (TRE/TRF), on bone health. This review is available in the British Journal of Nutrition.

7 Mar 2023

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer.

7 Mar 2023

Denosumab may benefit postmenopausal patients with hormone receptor-negative breast tumors and RANK protein expression

The drug denosumab is currently used to treat osteoporosis and bone metastases. For more than a decade, its potential therapeutic benefit in the treatment of breast cancer has also been studied.

7 Mar 2023

Age-associated B cells found to be important drivers of lupus

A group of University of Pittsburgh researchers has given new meaning to "knowing your ABCs."

3 Mar 2023

Guns are the biggest public health threat kids face. Why aren’t they getting the message?

I still remember the raspy voice of the wizened cancer patient with the hole in her throat. So addicted to the poison that was killing her — cigarettes — she interspersed her words of warning about the dangers of smoking with taking puffs of a cigarette through her tracheostomy hole.

3 Mar 2023