Inflammation News and Research

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Clinical study predicting risk of near-term MI and death in CAD patients to be published in JACC

FirstMark, a division of GenWay Biotech that is focused on developing and commercializing noninvasive diagnostic and health monitoring tests for unmet clinical needs, today announced that results from the break-through proof-of-concept clinical study, performed in collaboration with Emory University and MedStar Washington Hospital Center, will be published in the Journal of the American College of Cardiology.

9 May 2013

Special issue of Gastroenterology presents variety of topics related to pancreas

The editors of Gastroenterology, the official journal of the American Gastroenterological Association Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue.

9 May 2013

Phase 1b clinical study data of EBI-005 for treatment of dry eye disease presented at ARVO meeting

Eleven Biotherapeutics, a biopharmaceutical company designing and engineering novel and differentiated protein-based biotherapeutics for ocular diseases, announced today the presentation of data for EBI-005, the first IL-1 (Interleukin-1) signaling inhibitor designed for topical ocular administration, at the Association for Research in Vision and Ophthalmology 2013 Annual Meeting in Seattle, Washington.

9 May 2013

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque.

8 May 2013

Antidepressants can increase risk of C. difficile infection in depressed patients

Adults with depression and who receive certain types of anti-depressants have an increased risk of developing Clostridium difficile, a costly and serious hospital-associated infection, according to a new University of Michigan Health System study.

8 May 2013

New treatment could potentially benefit Irish SLE patients, find researchers

Researchers from the Royal College of Surgeons in Ireland have discovered that a new treatment for the inflammatory condition, Systemic Lupus Erythmstosus could potentially benefit Irish patients who suffer from the condition.

8 May 2013

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Aileron Therapeutics, Inc. today announced the completion of the first-in-human study of its lead Stapled Peptide drug, ALRN-5281, a proprietary, long-acting growth-hormone-releasing hormone (GHRH) agonist for treating orphan endocrine disorders, including adult growth hormone (GH) deficiency and human immunodeficiency virus (HIV) lipodystrophy, as well as broader patient populations involving a wide variety of metabolic/endocrine diseases.

7 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Ultrafine particles in consumer products can cause lung inflammation

A consortium of scientists from across the country has found that breathing ultrafine particles from a large family of materials that increasingly are found in a host of household and commercial products, from sunscreens to the ink in copy machines to super-strong but lightweight sporting equipment, can cause lung inflammation and damage.

7 May 2013

Researchers evaluate lung-related health impacts associated with engineered nanomaterials

For the first time, researchers from institutions around the country have conducted an identical series of toxicology tests evaluating lung-related health impacts associated with widely used engineered nanomaterials (ENMs).

7 May 2013

U-M launches new center for treating patients with critical conditions

America's emergency, trauma and intensive care teams provide some of the world's most advanced care, bringing patients back from the brink of death on a regular basis.

5 May 2013

EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced the issuance of a U.S. patent covering methods of treatment and formulations for its clinical-stage compound, 2-methoxyestradiol.

3 May 2013

Scientists spell out pivotal role of Peli1 in mouse model of multiple sclerosis

Scientists have identified an influential link in a chain of events that leads to autoimmune inflammation of the central nervous system in a mouse model of multiple sclerosis.

3 May 2013

Lund researchers develop new mouse model to better understand type 2 diabetes in humans

Researchers at Lund University in Sweden have developed a new mouse model that answers the question of what actually happens in the body when type 2 diabetes develops and how the body responds to drug treatment.

3 May 2013

Synthetic anti-inflammatory substances related to marijuana may help fight HIV infection

HIV, the virus that causes AIDS, is notorious for hiding within certain types of cells, where it reproduces at a slowed rate and eventually gives rise to chronic inflammation, despite drug therapy.

2 May 2013

Higher vitamin D levels confer no additional benefit

In recent years, healthy people have been bombarded by stories in the media and on health websites warning about the dangers of too-low vitamin D levels, and urging high doses of supplements to protect against everything from hypertension to hardening of the arteries to diabetes.

2 May 2013

Mayo Clinic researchers identify 27 genes that respond differently to rubella vaccine

Using advanced genetic sequencing technology and analysis, Mayo Clinic vaccine researchers have identified 27 genes that respond in very different ways to the standard rubella vaccine, making the vaccine less effective for a portion of the population.

2 May 2013

Hypothalamus controls aging throughout the body, scientists report

While the search continues for the Fountain of Youth, researchers may have found the body's "fountain of aging": the brain region known as the hypothalamus.

2 May 2013

PET/CT may enhance detection of inflammatory bowel diseases in the future

Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, may be detected and monitored more effectively in the future with positron emission tomography/computed tomography, according to research published in the May issue of The Journal of Nuclear Medicine.

2 May 2013

Scientists discover novel drug molecule that reduces swelling, inflammation in arthritic joints

A gas associated with the smell of rotten eggs has proven to effectively reduce joint swelling, in research which could lead to advances in the treatment of arthritis.

30 Apr 2013

Inflammation News and Research

Clinical study predicting risk of near-term MI and death in CAD patients to be published in JACC

Special issue of Gastroenterology presents variety of topics related to pancreas

Phase 1b clinical study data of EBI-005 for treatment of dry eye disease presented at ARVO meeting

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Antidepressants can increase risk of C. difficile infection in depressed patients

New treatment could potentially benefit Irish SLE patients, find researchers

Aileron Therapeutics concludes first-in-human study of ALRN-5281 Stapled Peptide drug

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Ultrafine particles in consumer products can cause lung inflammation

Researchers evaluate lung-related health impacts associated with engineered nanomaterials

U-M launches new center for treating patients with critical conditions

EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

Scientists spell out pivotal role of Peli1 in mouse model of multiple sclerosis

Lund researchers develop new mouse model to better understand type 2 diabetes in humans

Synthetic anti-inflammatory substances related to marijuana may help fight HIV infection

Higher vitamin D levels confer no additional benefit

Mayo Clinic researchers identify 27 genes that respond differently to rubella vaccine

Hypothalamus controls aging throughout the body, scientists report

PET/CT may enhance detection of inflammatory bowel diseases in the future

Scientists discover novel drug molecule that reduces swelling, inflammation in arthritic joints

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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