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Chemical hormone released due to stress can trigger mechanism for late onset of Alzheimer's disease

A chemical hormone released in the body as a reaction to stress could be a key trigger of the mechanism for the late onset of Alzheimer's disease, according to a study by researchers at Temple University.

20 Jun 2013

Penn researchers find ALS disease progresses in a stepwise, sequential pattern

The motor neuron disease Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology.

20 Jun 2013

EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Despite the fact that the incidence of cancer is many fold higher in persons over 65 years of age, we still have an inadequate understanding on how best to treat these older cancer patients. Furthermore, even though elderly patients are occasionally included in clinical trials, those elderly patients who are eventually included are mostly 'healthy' (fit) elderly patients.

20 Jun 2013

Oral probiotic supplement increases vitamin D levels in blood, says study

A study published in the Journal of Clinical Endocrinology & Metabolism is the first report of an oral probiotic supplement significantly increasing circulating vitamin D levels in the blood.

20 Jun 2013

Lumosity develops big data methodology for conducting human cognitive performance research

Lumosity, the leading brain training company, today announced a new web-based, big data methodology for conducting human cognitive performance research. Lumosity's research platform, the Human Cognition Project, contains the world's largest and continuously growing dataset of human cognitive performance, which currently includes more than 40 million people who have been tracked for up to 6 years.

20 Jun 2013

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

The National Institutes of Health has awarded $12.7 million to match nine academic research groups with a selection of pharmaceutical industry compounds to explore new treatments for patients in eight disease areas, including Alzheimer's disease, Duchenne muscular dystrophy and schizophrenia.

19 Jun 2013

Combination of obesity and low testosterone increases risk of diabetes and brain damage

Low testosterone worsens the harmful effects of obesity in the nervous system, a new study in mice finds. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

Viewpoints: Don't change course on Medicare reforms on medical equipment prices; Liberals' agenda depends on cutting entitlements; Making hospital prices public

Marilyn Tavenner has been administrator of Medicare and Medicaid officially for only about a month, but already she faces a policy challenge from Congress. A majority of the House, 145 Republicans and 82 Democrats, wrote to Ms. Tavenner on Wednesday, asking her to delay implementation of a Medicare cost-reduction initiative, scheduled to take full effect July 1, for six months.

18 Jun 2013

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes - the amyloid precursor protein and presenilins 1 and 2 - have been established as causative for inherited, early-onset Alzheimer's, accounting for about half of such cases.

18 Jun 2013

New study identifies possible treatment to block deposition of calcium in arterial wall

HGPS is a rare genetic disease that affects one in every 4-8 million births. The disease is caused by a spontaneous mutation in one of the two copies (alleles) of the gene LMNA, which codes for lamin A, a protein important for the integrity and function of the envelope surrounding the cell nucleus. The mutation causes incorrect processing of the messenger RNA for lamin proteins, resulting in the synthesis of an anomalous protein, called progerin.

18 Jun 2013

Early exposure to BPA increases risk for prostate cancer in human prostate tissue

Early exposure to BPA (bisphenol A) - an additive commonly found in plastic water bottles and soup can liners - causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.

18 Jun 2013

Researchers identify genetic mutation responsible for MDP Syndrome

National Paracycling Champion Tom Staniford has an extremely rare condition which, until now, has puzzled his doctors. He is unable to store fat under his skin - yet has type 2 diabetes - and suffered hearing loss as a child. Now, thanks to advances in genome sequencing, an international research team led by the University of Exeter Medical School has identified Tom's condition and pinpointed the single genetic mutation that causes it.

17 Jun 2013

UCSF researchers discover memory-boosting molecule in mice

Memory improved in mice injected with a small, drug-like molecule discovered by UCSF San Francisco researchers studying how cells respond to biological stress.

15 Jun 2013

Adults formerly treated for childhood cancer have chronic health problems

In an analysis that included more than 1,700 adult survivors of childhood cancer, researchers found a very high percentage of survivors with 1 or more chronic health conditions, with an estimated cumulative prevalence of any chronic health condition of 95 percent at age 45 years, according to a study in the June 12 issue of JAMA.

14 Jun 2013

Research: Older adults who volunteer for work decrease their risk of hypertension

New research from Carnegie Mellon University shows that older adults who volunteer for at least 200 hours per year decrease their risk of hypertension, or high blood pressure, by 40 percent.

14 Jun 2013

Research: Sleep mechanism enables brain to consolidate emotional memory

Sleep researchers from University of California campuses in Riverside and San Diego have identified the sleep mechanism that enables the brain to consolidate emotional memory and found that a popular prescription sleep aid heightens the recollection of and response to negative memories.

13 Jun 2013

African-Americans have much greater decrease in their sense of smell, study finds

The ability to distinguish between odors declines steadily with age, but a new study shows that African-Americans have a much greater decrease in their sense of smell than Caucasians.

13 Jun 2013

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Alzheimer's disease has been linked in many studies to amyloid plaque buildup in the brain, but new research is finding a common thread between amyloid burden and lower energy levels, or metabolism, of neurons in certain areas of the brain associated with Alzheimer's disease-even for people with no sign of cognitive decline.

12 Jun 2013

Scheduled exercise, regular meals and periodic warming relieve symptoms of osteoarthritis

Scheduled exercise, regular meals and the periodic warming and cooling of joints could be used to relieve the symptoms of osteoarthritis according to scientists at The University of Manchester. Their research may also help explain why older people are more prone to developing this common joint disorder.

12 Jun 2013

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

The numbers in the Rand study ... should not be a surprise to people who have been paying attention. Numerous studies now, including in Missouri, have pointed to the simple reality of the policy implications of the ACA to argue for Medicaid expansion.

12 Jun 2013

Aging News and Research

Chemical hormone released due to stress can trigger mechanism for late onset of Alzheimer's disease

Penn researchers find ALS disease progresses in a stepwise, sequential pattern

EORTC starts phase 2 trial in elderly patients with HER-2 positive metastatic breast cancer

Oral probiotic supplement increases vitamin D levels in blood, says study

Lumosity develops big data methodology for conducting human cognitive performance research

NIH awards $12.7M to research groups to explore new treatments for patients in eight disease areas

Combination of obesity and low testosterone increases risk of diabetes and brain damage

Viewpoints: Don't change course on Medicare reforms on medical equipment prices; Liberals' agenda depends on cutting entitlements; Making hospital prices public

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

New study identifies possible treatment to block deposition of calcium in arterial wall

Early exposure to BPA increases risk for prostate cancer in human prostate tissue

Researchers identify genetic mutation responsible for MDP Syndrome

UCSF researchers discover memory-boosting molecule in mice

Adults formerly treated for childhood cancer have chronic health problems

Research: Older adults who volunteer for work decrease their risk of hypertension

Research: Sleep mechanism enables brain to consolidate emotional memory

African-Americans have much greater decrease in their sense of smell, study finds

Hypometabolism in brain regions of cognitively normal patients associated with Alzheimer's disease

Scheduled exercise, regular meals and periodic warming relieve symptoms of osteoarthritis

Viewpoints: Medicaid expansion 'makes sense'; Budget cuts hurt Alzheimer's research; Lack of transparency in generic Rx prices

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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