Efficacy News and Research

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Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

Deuteration offers alternative chorea treatment for Huntington disease patients

Treatment with a deuterated form of tetrabenazine has resulted in improved motor signs among patients with Huntington disease, making it a potential treatment for chorea, trial findings show.

6 Jul 2016

Immobilisation after intrauterine insemination has no beneficial effect on pregnancy rates in women

Despite the positive results of small studies and a widely held belief in its benefit, the practice of keeping female patients immobilised after intrauterine insemination has no beneficial effect on pregnancy rates, according to results of a large randomised study presented here at the Annual Meeting of ESHRE in Helsinki.

5 Jul 2016

Celltrion Healthcare commits to develop lab tests for evidence-based decision-making in anti-TNF treatment

Celltrion Healthcare, a global biopharmaceutical company, today announced its research commitment to develop laboratory tests that will determine both drug and anti-drug antibody levels in the blood, enabling physicians to identify when patients on an anti-tumour necrosis factor drug require a change of dose or a switch to a different treatment in the class.

5 Jul 2016

AOSSM presents research awards, grants at annual meeting

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine will present research awards and grants during its Annual Meeting, July 7-10 in Colorado Springs, CO.

5 Jul 2016

First-line nivolumab promising in advanced NSCLC

Phase I results published in the Journal of Clinical Oncology suggest that nivolumab, either given alone or alongside platinum-based doublet chemotherapy, could have a role in the first-line treatment of advanced non-small-cell lung cancer.

5 Jul 2016

Study examines effects of lifestyle-intervention in obese women undergoing fertility treatment

Women who are overweight or obese pose an ongoing challenge for the fertility clinic. Many studies show that these patients are at increased risk of infertility and are less likely than normal-weight women to conceive after fertility treatment.

4 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

Report highlights need to strengthen response to major public health threats

In a report released today by the U.S. Department of Health and Human Services, an Independent Panel formed to review HHS's response to Ebola made several recommendations on how the nation's federal public health system should strengthen its response to major public health threats, both internationally and domestically.

1 Jul 2016

Advances in inhaled drug delivery: an interview with Dr Robert Clarke

Delivering drugs to the lungs via inhalation has a number of potential advantages over traditional routes of administration like pills or injections. For treating pulmonary diseases, the obvious logic we are applying is topical delivery to the airways via inhalation.

1 Jul 2016

Virtual reality games fail to outplay card and ball games in stroke rehabilitation

Researchers have found inexpensive recreational activities such as playing cards or ball games are as effective add-on therapies to conventional stroke rehabilitation as virtual reality interventions.

1 Jul 2016

Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Oral multikinase inhibitor regorafenib achieves significantly improved survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase III RESORCE trial, presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

30 Jun 2016

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

The targeted therapy everolimus may be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma according to the results of a pilot study by Mayo Clinic researchers published in the Lancet Haematology.

30 Jun 2016

Transorbital ACS can improve vision in patients with glaucoma, optic nerve damage

Vision loss due to glaucoma or optic nerve damage is generally considered irreversible. Now a new prospective, randomized, multi-center clinical trial demonstrates significant vision improvement in partially blind patients after 10 days of noninvasive, transorbital alternating current stimulation.

30 Jun 2016

ADAPT technique offers promising outcomes for stroke patients with large-vessel clots

In an article published online April 16, 2016 by the Journal of Neurointerventional Surgery, investigators at the Medical University of South Carolina report promising 90-day outcomes for stroke patients with large-vessel clots who underwent thrombectomy or clot removal using the direct-aspiration, first pass technique.

30 Jun 2016

Researcher receives federal grant to advance study of tumor nanoimmunology

The five-year grant was awarded by the National Cancer Institute of the National Institutes of Health. The funds come on top of four previous grants to support Ljubimova's work. In all, the institute has awarded Ljubimova $16.5 million over the last five years.

29 Jun 2016

Efficacy News and Research

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Deuteration offers alternative chorea treatment for Huntington disease patients

Immobilisation after intrauterine insemination has no beneficial effect on pregnancy rates in women

Celltrion Healthcare commits to develop lab tests for evidence-based decision-making in anti-TNF treatment

AOSSM presents research awards, grants at annual meeting

First-line nivolumab promising in advanced NSCLC

Study examines effects of lifestyle-intervention in obese women undergoing fertility treatment

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

Report highlights need to strengthen response to major public health threats

Advances in inhaled drug delivery: an interview with Dr Robert Clarke

Virtual reality games fail to outplay card and ball games in stroke rehabilitation

Regorafenib drug improves survival rates in patients with hepatocellular carcinoma

Everolimus combined with standard R-CHOP therapy shows promise in treating DLBCL patients

Transorbital ACS can improve vision in patients with glaucoma, optic nerve damage

ADAPT technique offers promising outcomes for stroke patients with large-vessel clots

Researcher receives federal grant to advance study of tumor nanoimmunology

MOOD-HF supports lack of antidepressant efficacy in HF patients

Pharmacotherapy reduces conduction system disease risk

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

'Novel' analysis addresses antiplatelet benefits in real-world CHD patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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