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New study: Fast food meal consumption can affect inflammatory responses in blood vessels

The effect of a high-fat meal on blood vessel walls can vary among individuals depending on factors such as their waist size and triglyceride levels, suggests new research at UC Davis.

17 Feb 2011

FAK enzyme plays a key role in preparing lung tissue for metastatic development

A Massachusetts General Hospital study has identified a new role for an important enzyme in preparing lung tissue for the development of metastases.

17 Feb 2011

New fully human monoclonal antibodies to battle Chikungunya

The Singapore Immunology Network (SIgN), an institute of the Agency of Science, Technology and Research (A*STAR), and VIVALIS, a French biopharmaceutical company, announced today the discovery of two new fully human monoclonal antibodies which could battle Chikungunya, a disease that currently has no available vaccine or specific treatment.

16 Feb 2011

Study explores role of proline containing peptides in inhibiting anti-apoptotic function of XIAP

Basic and translational research on cancer, and development of new cancer therapeutics, has focused on different aspects of cancer cellular function. One area of focus is the life and death of a cancer cell. Apoptosis, also known as programmed cell death, is a fundamental process of cells including cancer cells. The signal transduction pathways of apoptosis involve many different proteins and their interactions with each other.

16 Feb 2011

Viral Genetics' lead researcher, Advisor to receive Lauren F. Brooks Hope Award

Viral Genetics, Inc. announced today that lead researcher Dr. M. Karen Newell Rogers and Advisor Mr. Richard Gerstner will receive the Lauren F. Brooks Hope Award, presented by Time for Lyme, Inc.

16 Feb 2011

NGDI-UBC, CDRD partner for drug development platform to treat neglected global diseases

The Centre for Drug Research and Development and the Neglected Global Diseases Initiative at the University of British Columbia today announced that they will collaborate on developing interventions for neglected global diseases and ensuring their delivery to those in need.

16 Feb 2011

EMBL scientists reveal new insights into bacterial enzymes that causes tuberculosis

In a paper published today in PNAS, scientists from the European Molecular Biology Laboratory in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis.

15 Feb 2011

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

In cancer and other pathological diseases, researchers are discovering that packaging is important: specifically, how DNA - about two meters long when unwound and stretched - coils up and compacts neatly inside the nucleus of a cell.

15 Feb 2011

Evotec partners with ChemBridge to expand high throughput screening collection

Evotec AG today announced that it has entered into a collaboration with ChemBridge to further enhance its screening library. This collaboration demonstrates Evotec's continued improvement to its industry leading hit identification platform.

15 Feb 2011

Researcher discovers mechanism how p53 human genome gets inactivated in cancerous cells

One of the most important genes in the human genome is called p53 and its function is to suppress tumours, according to Roger Leng, a researcher in the Faculty of Medicine & Dentistry. Leng has discovered the mechanism by which p53 is inactivated in cancerous cells, allowing tumours to grow.

15 Feb 2011

Study shows lower success rate of FDA drug approval from 2003 to 2010

Biotechnology Industry Organization Industry Analysis and BioMedTracker announced results of a study today that shows the overall success rate for drugs moving through clinical trials to FDA approval from late 2003 to the end of 2010 is near one in 10. Previous reports, taken from earlier years, showed the rate of drug approvals is one in five to one in six.

15 Feb 2011

Public-sector research has had an immediate effect on improving public health: Study

AUTM President Ashley Stevens, D. Phil. (Oxon), CLP is the lead author of The Role of Public Sector Research in the Discovery of Drugs and Vaccines, a paper published in the Feb. 10 issue of The New England Journal of Medicine.

14 Feb 2011

Novel technology to diagnose Alzheimer's disease before symptoms appear

UT Southwestern Medical Center scientists have helped develop a novel technology to diagnose Alzheimer's disease from blood samples long before symptoms appear.

14 Feb 2011

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have produced the first known compound to show significant effectiveness in protecting brain cells directly affected by Parkinson's disease, a progressive and fatal neurodegenerative disorder.

13 Feb 2011

Study sheds new light on riboswitch that turns genes on or off in response to cell's energy needs

Scientists from The Scripps Research Institute have shed new light on a molecular switch that turns genes on or off in response to a cell's energy needs.

13 Feb 2011

Blocking interleukin 15 may help restore oral tolerance to gluten

Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease in those most at risk, researchers report in the journal Nature.

11 Feb 2011

Anacor, Medicis collaborate to discover and develop boron-based treatment for acne

Anacor Pharmaceuticals, Inc. and Medicis Pharmaceutical Corporation today announced that the two companies have entered into a research and development agreement to discover and develop boron-based small molecule compounds directed against a target for the potential treatment of acne.

11 Feb 2011

Intellikine, PKD Foundation to investigate novel therapies for patients with PKD

Intellikine, a leader in the development of small molecule drugs targeting the PI3K/mTOR pathway, and the PKD Foundation today announced a collaboration to investigate novel, orally-available small molecule kinase inhibitors of the TORC1 and TORC2 complexes as a potential treatment for patients with polycystic kidney disease.

11 Feb 2011

Patients with high blood pressure have benign endocrine tumours in adrenal gland: Research

High blood pressure may in some cases be caused by benign hormone-producing tumours of the adrenal cortex. A joint Swedish-American research effort has now uncovered a genetic cause behind the occurrence of such tumours. The findings were published today in the journal Science.

11 Feb 2011

Study: New curcumin-hybrid compound may help protect, regenerate brain cells after stroke

Whether or not you're fond of Indian, Southeast Asian and Middle Eastern food, stroke researchers at Cedars-Sinai Medical Center think you may become a fan of one of their key spices.

10 Feb 2011

Molecule News and Research

New study: Fast food meal consumption can affect inflammatory responses in blood vessels

FAK enzyme plays a key role in preparing lung tissue for metastatic development

New fully human monoclonal antibodies to battle Chikungunya

Study explores role of proline containing peptides in inhibiting anti-apoptotic function of XIAP

Viral Genetics' lead researcher, Advisor to receive Lauren F. Brooks Hope Award

NGDI-UBC, CDRD partner for drug development platform to treat neglected global diseases

EMBL scientists reveal new insights into bacterial enzymes that causes tuberculosis

Researchers use computers to capture chemical signal structure that triggers metastatic cancer

Evotec partners with ChemBridge to expand high throughput screening collection

Researcher discovers mechanism how p53 human genome gets inactivated in cancerous cells

Study shows lower success rate of FDA drug approval from 2003 to 2010

Public-sector research has had an immediate effect on improving public health: Study

Novel technology to diagnose Alzheimer's disease before symptoms appear

Scientists produce SR-3306 compound to protect brain cells from Parkinson's disease

Study sheds new light on riboswitch that turns genes on or off in response to cell's energy needs

Blocking interleukin 15 may help restore oral tolerance to gluten

Anacor, Medicis collaborate to discover and develop boron-based treatment for acne

Intellikine, PKD Foundation to investigate novel therapies for patients with PKD

Patients with high blood pressure have benign endocrine tumours in adrenal gland: Research

Study: New curcumin-hybrid compound may help protect, regenerate brain cells after stroke

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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