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Liposome nanoencapsulation can increase efficacy of bacteriophages in oral phage therapy

Scientists at the Universitat Autònoma de Barcelona and the Catalan Institute for Nanoscience and Nanotechnology have developed a nanoencapsulation system with a liposome coating in order to increase the efficacy of bacteriophages in oral phage therapy.

14 Jun 2016

Topical delivery of AVR drug combination can provide complete protection against HIV

Researchers are edging ever closer to discovering the perfect combination of drugs and drug delivery system that will stop the sexual transmission of HIV.

14 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

New experimental antibiotic can help combat MRSA infections

A new experimental antibiotic developed by a team of scientists at Rutgers University successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA.

14 Jun 2016

Clinical trial to test efficacy of new drug for chronic cough

The National Institute for Health Research has today announced its participation in a clinical trial to test a promising new treatment for chronic cough. If approved, this would be the first new cough drug in 50 years and offer hope to the millions of people living with chronic cough for whom few, if any, effective treatments exist.

14 Jun 2016

Study opens up new strategy to make immunotherapy more effective for different cancer types

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago, working with mice, were able to increase the response rate for these new immunotherapy agents.

14 Jun 2016

Novel radioimmunotherapy may help cure colorectal cancer

An emerging cancer therapy has colorectal tumors surrounded. Presenters at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging are unveiling a novel radioimmunotherapy that combines a cancer-seeking antibody with potent radionuclide agents, resulting in complete remission of colorectal cancer in mouse models.

14 Jun 2016

Age no barrier to vorapaxar use in ACS

The protease-activated receptor 1 inhibitor vorapaxar offers the same benefits to older and younger patients with non-ST segment elevation acute coronary syndromes, shows further analysis of the TRACER trial.

14 Jun 2016

Anti-TNF therapy offers new hope to JDM patients

The results of a UK study presented today at the European League Against Rheumatism Annual Congress showed that tumour necrosis factor inhibitor (anti-TNF) treatment is effective at improving both muscle and skin involvement in children with juvenile dermatomyositis (JDM).

13 Jun 2016

FDA approves Vaxchora for prevention of cholera

The U.S. Food and Drug Administration today approved Vaxchora, a vaccine for the prevention of cholera caused by serogroup O1 in adults 18 through 64 years of age traveling to cholera-affected areas. Vaxchora is the only FDA-approved vaccine for the prevention of cholera.

13 Jun 2016

New controlled drug release system could revolutionize success rate of vascular bypasses

Coronary or peripheral bypasses are the most frequently performed vascular operations. Although one million patients per year and around the world, undergo this intervention, its failure rate reaches 50%, because of poor vessel healing, leading to vessel graft occlusion.

13 Jun 2016

New method helps speed up bacterial identification

Pinpointing the type of bacteria that are at the root of an infection in clinical samples removed from living tissues, such as blood, urine or joint fluids, to quickly identify the best anti-microbial therapy still poses a formidable challenge.

10 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

New drug ixekizumab helps clear severe psoriasis symptoms

About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical trials led by Northwestern Medicine.

10 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago.

9 Jun 2016

Efficacy News and Research

Liposome nanoencapsulation can increase efficacy of bacteriophages in oral phage therapy

Topical delivery of AVR drug combination can provide complete protection against HIV

EPFL researchers reprogram TAMs to prevent tumor metastasis

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

New experimental antibiotic can help combat MRSA infections

Clinical trial to test efficacy of new drug for chronic cough

Study opens up new strategy to make immunotherapy more effective for different cancer types

Novel radioimmunotherapy may help cure colorectal cancer

Age no barrier to vorapaxar use in ACS

Anti-TNF therapy offers new hope to JDM patients

FDA approves Vaxchora for prevention of cholera

New controlled drug release system could revolutionize success rate of vascular bypasses

New method helps speed up bacterial identification

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

New drug ixekizumab helps clear severe psoriasis symptoms

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Migraine drug has quick onset of action

Coagadex now available for rare bleeding disorder patients in the UK

Existing immunotherapy drug pembrolizumab shows promise for specific sarcoma subtypes

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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