Protein C News and Research

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Role of host gene variants in COVID-19 severity

A new study discusses the importance of common, rare, and intermediate variants of several host genes to the clinical severity of infection with SARS-CoV-2.

20 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

A large international collaboration led by researchers from the Johns Hopkins Kimmel Cancer Center has identified promising new targets for pancreatic cancer treatment and early diagnosis after examining various aspects of these tumors' genes and proteins.

20 Sep 2021

T cell immunity induced after mild COVID could contribute to protection against re-infection

An interesting new study finds that in both adults and children, a mild infection with the SARS-CoV-2 elicits an antigen-specific memory T-cell response.

20 Sep 2021

What impact has SARS-CoV-2 variant B.1.1.519 had on Mexico City?

The current study reports the effective reproduction number of B.1.1.519 and presents its geographical origin based on phylogenetic analysis.

20 Sep 2021

SARS-CoV-2 antibody models describe differences between the kinetics of different antibodies

Researchers have created kinetic models of IgG and IgM anti-SARS-CoV-2 antibodies over 13.5 months following infection to understand long-lasting immunity better.

20 Sep 2021

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

Researchers from the University of Southern California investigated mutations in the N-terminal and RBD domains of the spike protein.

20 Sep 2021

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

In a recent study, scientists have tested the hypothesis that indicates the role of polyP in the COVID-19 mRNA vaccine-induced immune responses.

20 Sep 2021

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

Allergic reactions to the new mRNA-based COVID-19 vaccines are rare, typically mild and treatable, and they should not deter people from becoming vaccinated, according to research from the Stanford University School of Medicine.

20 Sep 2021

New discovery reveals how immune 'sentinel' cells are maintained

WEHI researchers have made a surprise discovery about how immune 'sentinel' cells are maintained, which could have implications for drugs in development for treating cancer.

20 Sep 2021

Research on SARS-CoV-2 and dendritic cells may explain why virus is so virulent

In a recent study released on the bioRxiv* preprint server, the researchers suggest that an aberrant inflammatory reaction associated with COVID-19 could be a result of escape from direct sensing by toll-like receptors (TLRs). Moreover, the researchers indicate that this phenomenon might underlie the lack of efficient immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early during infection.

20 Sep 2021

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

A new study posted to the bioRxiv* server attempted to explore anti-spike IgG responses, Fc-gamma receptor (FcγR) activation, IgG targeting of immunodominant regions, and recall responses due to seasonal hCoV infections in non-hospitalized COVID-19 patients.

20 Sep 2021

Protein C News and Research

Role of host gene variants in COVID-19 severity

Two proteins work in tandem to build lifelines to cancer cells, study finds

Large scale 'proteogenomics' study could offer hope to patients with deadly pancreatic cancer

T cell immunity induced after mild COVID could contribute to protection against re-infection

What impact has SARS-CoV-2 variant B.1.1.519 had on Mexico City?

SARS-CoV-2 antibody models describe differences between the kinetics of different antibodies

Novel spike NTD mutations in SARS-CoV-2 Delta variant associated with increased viral loads and immune evasion

First dose of COVID-19 mRNA vaccine (BNT162b2) reduced platelet polyP levels in young females

COVID-19 vaccine-related allergies are rare, typically mild and treatable, finds study

New discovery reveals how immune 'sentinel' cells are maintained

Research on SARS-CoV-2 and dendritic cells may explain why virus is so virulent

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

Characterizing the flexibility of SARS-CoV-2 variant of concern spike proteins

A new synthetic multiantigen MVA vaccine COH04S1 effective against SARS-CoV-2

Researchers report on under-sequenced region of S gene of the SARS-CoV2 Delta variant

Study shows efficacy of mRNA vaccines against SARS-CoV-2 in individuals with obesity

New data shows benefit of drug combination for metastatic castration resistant prostate cancer

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

Researchers discover new mechanism used by a simple yeast cell to acquire its shape

Research reveals a possible new treatment approach for pediatric rhabdomyosarcoma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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