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New antibiotic compound can effectively clear multi-drug resistant gonorrhea in animals

A new antibiotic compound clears infection of multi-drug resistant gonorrhea in mice in a single oral dose, according to a new study led by researchers at Penn State and Emory University.

19 Mar 2021

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Atypical teratoid rhabdoid tumor (ATRT) is a rare brain tumor that predominantly occurs in young children. Scientists at St. Jude Children's Research Hospital used data from two clinical trials to study the molecular groups of ATRT and correlate them with clinical outcomes.

19 Mar 2021

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Alliance for Cancer Gene Therapy wants to change the C-word from Cancer to Cure -- building on the life changing success of CAR-T therapies for blood cancers, the organization is now focused on the urgent need to translate this success into therapies to fight more types of cancer, such as solid tumor cancers.

19 Mar 2021

Lower dose of tamoxifen may reduce risk of breast cancer

While the drug tamoxifen reduces the risk of developing breast cancer and prevents recurrence, the side-effects cause many women to discontinue their treatment.

19 Mar 2021

Chemical cocktail shows promise for producing muscle stem cells

A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.

19 Mar 2021

Study: Transcendental meditation can significantly reduce severity of PTSD symptoms

Veterans with PTSD who practiced the Transcendental Meditation technique showed significant reductions in PTSD symptom severity, according to a new study published today in Journal of Traumatic Stress.

19 Mar 2021

Study explores how CAR T immunotherapy could be used to treat solid tumors

A study recently published in the journal Science looked into how CAR T immunotherapy could be used to treat solid tumors in addition to leukemias. The programming of CAR T cells opens avenues for applying cell therapies to, for example, breast cancer or ovarian cancer in the future.

18 Mar 2021

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre.

18 Mar 2021

Rumination syndrome often confused with other gastrointestinal conditions

Patients who regurgitate regularly but without any known cause may have a condition called rumination. Unfortunately, rumination is often confused with other gastrointestinal conditions, which means many patients may not be getting prompt treatment.

18 Mar 2021

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease.

18 Mar 2021

Novel cancer-fighting gene therapy enters phase I clinical trial

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells.

18 Mar 2021

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

A recent study found that the Pfizer-BioNTech mRNA vaccine had limited efficacy in identifying mutated receptor-binding domains (RBDs) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein similar to the B.1.351 and P.1 variants.

18 Mar 2021

Could cinnamon modulate the immune response in severe COVID-19?

A new study describes the potential for two common plant products to make a difference in the management of severe COVID-19.

18 Mar 2021

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

Caused by SARS-CoV-2, the ongoing COVID-19 pandemic has led to over 121.2 million cases and over 2.6 million deaths worldwide. An interesting new study examines the potential antiviral activity of compounds present in the plant Artemisia annua L.

18 Mar 2021

Scientists develop series of heart valve replacements to implant host cells into lambs

Combining tissue engineering and regenerative medicine, scientists have fabricated a series of heart valve replacements with the ability to incorporate host cells, enabling them to regenerate and grow over time.

18 Mar 2021

New way to enhance treatment outcomes for breast cancer

Breast cancer is the most common cancer in women worldwide and the second most common cancer overall. Although it can now be treated with drugs, many of these drugs mysteriously stop working after some time, causing a relapse.

18 Mar 2021

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

Oncotarget published "Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma" which reported that prior work has characterized changes in the mutation burden between primary and recurrent tumors; however, little work has characterized the changes in neoantigen evolution.

18 Mar 2021

Statistical suicide risk prediction models could be cost-effective and save many lives

There are several effective interventions to reduce the risk of suicide, the tenth-leading cause of death in the United States, but difficulties in identifying people at risk for suicide and concerns about the potentially high costs of suicide-prevention strategies have hampered their wider use.

17 Mar 2021

Beneficial effects of gene therapy can be seen in SCID-X1 patients decades after treatment

An international collaboration between Great Ormond Street Hospital, the UCL GOS Institute for Child Health and Harvard Medical School has shown that the beneficial effects of gene therapy can be seen decades after the transplanted blood stem cells has been cleared by the body.

17 Mar 2021

Doctors debate use of blood thinners to prevent clots in women after C-sections

Nearly all women who deliver babies through cesarean section at Columbia University Irving Medical Center in New York City receive injections of the blood thinner heparin for weeks after the procedure, to prevent potentially life-threatening blood clots.

17 Mar 2021

Therapy News and Research

New antibiotic compound can effectively clear multi-drug resistant gonorrhea in animals

Scientists use clinical data to study the molecular groups of atypical teratoid rhabdoid tumor

Alliance for Cancer Gene Therapy provides new opportunity to develop cancer cell and gene therapies

Lower dose of tamoxifen may reduce risk of breast cancer

Chemical cocktail shows promise for producing muscle stem cells

Study: Transcendental meditation can significantly reduce severity of PTSD symptoms

Study explores how CAR T immunotherapy could be used to treat solid tumors

Antidiabetic drug could help reduce chronic inflammation in people living with HIV

Rumination syndrome often confused with other gastrointestinal conditions

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

Novel cancer-fighting gene therapy enters phase I clinical trial

SARS-CoV-2 variants with E484K mutation show mRNA vaccine-induced antibody evasion

Could cinnamon modulate the immune response in severe COVID-19?

Do Artemisia annua L. compounds have SARS-CoV-2 antiviral potential?

Scientists develop series of heart valve replacements to implant host cells into lambs

New way to enhance treatment outcomes for breast cancer

Study characterizes shifting neoantigen burden between primary and metastatic tumors within HNSCC

Statistical suicide risk prediction models could be cost-effective and save many lives

Beneficial effects of gene therapy can be seen in SCID-X1 patients decades after treatment

Doctors debate use of blood thinners to prevent clots in women after C-sections

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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