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Scientists find molecular cocktail to transform non-muscle cells into cardiac muscle

In heart disease, cardiac muscle gradually dies off and, with little or no way to regenerate those cells, that can ultimately lead the heart to fail. But scientists reporting in the August 6th issue of Cell, a Cell Press publication, might have found a way to fix those losses. They've devised a three-ingredient molecular cocktail that transforms fibroblasts - structural cells that the heart is chock full of - directly into beating heart cells.

6 Aug 2010

Repligen total revenue for first-quarter fiscal 2011 increases 39% to $7.01 million

Repligen Corporation today reported results for the first quarter of fiscal year 2011, ended June 30, 2010. Total revenue for the first quarter was $7,010,000 compared to total revenue of $5,061,000 for the first quarter of fiscal year 2010, an increase of $1,949,000 or 39%. Bioprocessing product revenue for the first quarter was $4,269,000 compared to $2,473,000 for the first quarter of fiscal 2010, an increase of $1,796,000 or 73%.

5 Aug 2010

Genomic sequence of living marine sponge reveals some basic information about cancer: Scientists

This week's publication of the complete genomic sequence of a living marine sponge reveals genes dating back hundreds of millions of years -- a result far exceeding the expectations of the scientific world.

5 Aug 2010

Abiomed first-quarter fiscal 2011 revenue increases 11% to $22.0 million

Abiomed, Inc., a leading provider of breakthrough heart support technologies, today reported first quarter fiscal 2011 revenue of $22.0 million, up 11% compared to the same period of fiscal 2010.

5 Aug 2010

Certain proteins, genes play key role in regenerating lost body parts: Research

Another option may be on the horizon for patients who lose limbs due to war, accident, or disease. Instead of using artificial legs or arms, patients actually may regrow their own missing limbs. An article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine, focuses on research efforts to turn the long-standing dream of human limb regeneration into reality.

5 Aug 2010

Long-term exposure to valproate leads to bone loss: Study

Scientists are reporting a possible explanation for the bone loss that may occur following long-term use of a medicine widely used to treat epilepsy, bipolar disorder, and other conditions. The drug, valproate, appears to reduce the formation of two key proteins important for bone strength, they said. Their study, which offers a solution to a long-standing mystery, appears in ACS' monthly Journal of Proteome Research.

5 Aug 2010

Tips for healthy eating at college

For college students, the campus dining hall offers a tantalizing feast: ice-cream sundaes every night, thirty varieties of cereal and a limitless supply of french fries."It's like a smorgasborg on a cruise ship," said Cynthia Bulik, PhD, director of the Eating Disorders Program at the UNC School of Medicine. All-you-can-eat dining halls, along with changes in exercise habits, have been blamed for the "freshman 15," in which first-year students gain weight.

5 Aug 2010

Acceleron's ACE-031 protein therapeutic for DMD receives FDA Fast Track designation

Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including muscle, bone, fat, red blood cells and the vasculature, today announced it received FDA Fast Track designation for ACE-031 for the treatment of Duchenne Muscular Dystrophy (DMD), a fatal neuromuscular disease in which patients suffer from the progressive loss of muscle mass and strength. ACE-031 is an investigational protein therapeutic being developed to increase muscle mass and strength.

5 Aug 2010

Fractures are major concern for U.S. high school athletes: Study

The popularity of high school sports in the United States has continued to increase over the past decade, with more than 7.5 million athletes participating in school sports during the 2008-09 academic year. A new study conducted by the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital found that 95 percent of fractures required costly diagnostic imaging, including X-rays, MRIs and CT scans, and 16 percent required surgical repair.

4 Aug 2010

New article published in Journal of Surgical Research highlights PACE technology

SANUWAVE Health, Inc., an emerging medical technology company focused on the development and commercialization of non-invasive, biological response activating devices in regenerative medicine, today announced that an article titled "Microvascular Response to Shock Wave Application in Striated Skin Muscle" was recently published in the on-line edition of the Journal of Surgical Research.

4 Aug 2010

Exercise, restricted-calorie diets help to stave off mental, physical degeneration of aging: Research

Harvard University researchers have uncovered a mechanism through which caloric restriction and exercise delay some of the debilitating effects of aging by rejuvenating connections between nerves and the muscles that they control.

3 Aug 2010

miRagen Therapeutics develop MicroRNA based therapeutics for cardiovascular and muscle disease

miRagen Therapeutics, Inc., a biopharmaceutical company focused on improving patients' lives by developing innovative microRNA-based therapeutics for cardiovascular and muscle disease, announced today the publication of data demonstrating the essential role of microRNA-451 (miR-451) in the regulation of erythropoiesis, the process of red blood cell production in the body.

3 Aug 2010

Biomaterials-based bone grafts can manipulate cell behavior to repair injury

Scientists have developed a material for bone grafts that could one day replace the 'gold standard' natural bone implants.A new study shows how particles of a ceramic called calcium phosphate have the ability to stimulate promising bone regrowth by attracting stem cells and 'growth factors' to promote healing and the integration of the grafted tissue.

3 Aug 2010

Research links body weight to glaucoma risk

This month's Ophthalmology journal includes surprising research from the Massachusetts Eye and Ear Infirmary on the relation of body weight to the risk for glaucoma. Also, from researchers at the Tokyo Medical and Dental University, comes the first specific map of how the development of myopic maculopathy, an illness that afflicts many severely nearsighted people, predicts which patients will be most susceptible to vision loss.

3 Aug 2010

Australian scientists uncover the secrets behind one of nature’s most extraordinary biological machines

Scientists from the Victor Chang Cardiac Research Institute (VCCRI), Sydney, have discovered the secrets behind the tiny motors in bacteria that allow them to swim rapidly towards nutrients and away from toxins, which is crucial to the spread of bacterial infection. These motors can rotate at up to 100,000 revolutions per minute, yet can switch directions in milliseconds.

1 Aug 2010

Scientists reveal origins of second heart field in vertebrates

Using the model organism Ciona intestinalis, commonly known as the sea squirt, researchers at the University of California, Berkeley, have uncovered the origins of the second heart field in vertebrates.

31 Jul 2010

Patients with malignant gastrointestinal disease show high prevalence of malnutrition

Malnutrition is an important factor, influencing both morbidity and recovery after surgery. The early detection of nutritional risk would allow early intervention, which may prevent later complications. A traditional nutritional assessment often includes dietary and medical evaluations to identify significant weight loss over time, significantly low or high body weight(BW), skinfold thickness, serum nutritional factor levels and functional measurements of muscle strength.

31 Jul 2010

Chemical compound provides new angle for developing drugs to treat seizures: Study

A chemical compound that boosts the action of a molecule normally produced in the brain may provide the starting point for a new line of therapies for the treatment of epileptic seizures, according to a new study by scientists at The Scripps Research Institute.

30 Jul 2010

Shionogi's CUVPOSA receives FDA approval for treatment of chronic severe drooling

Shionogi Inc., a U.S.-based group company of Shionogi & Co., Ltd., today announced the U.S. Food and Drug Administration approval of CUVPOSA™ (glycopyrrolate), the first liquid treatment for patients ages 3-16 who suffer from chronic severe drooling associated with neurologic conditions such as cerebral palsy. CUVPOSA™ was designated an Orphan Drug by the FDA.

30 Jul 2010

Advanced Protein Systems is now APS BioGroup

APS BioGroup, formerly Advanced Protein Systems, the world's largest producer of colostrum products, announces its new company name and expanded focus to include advancements in private label contract manufacturing for health supplements and the introduction of Immulox®, an immune support product and supplement ingredient derived from colostrum.

29 Jul 2010

Muscle News and Research

Scientists find molecular cocktail to transform non-muscle cells into cardiac muscle

Repligen total revenue for first-quarter fiscal 2011 increases 39% to $7.01 million

Genomic sequence of living marine sponge reveals some basic information about cancer: Scientists

Abiomed first-quarter fiscal 2011 revenue increases 11% to $22.0 million

Certain proteins, genes play key role in regenerating lost body parts: Research

Long-term exposure to valproate leads to bone loss: Study

Tips for healthy eating at college

Acceleron's ACE-031 protein therapeutic for DMD receives FDA Fast Track designation

Fractures are major concern for U.S. high school athletes: Study

New article published in Journal of Surgical Research highlights PACE technology

Exercise, restricted-calorie diets help to stave off mental, physical degeneration of aging: Research

miRagen Therapeutics develop MicroRNA based therapeutics for cardiovascular and muscle disease

Biomaterials-based bone grafts can manipulate cell behavior to repair injury

Research links body weight to glaucoma risk

Australian scientists uncover the secrets behind one of nature’s most extraordinary biological machines

Scientists reveal origins of second heart field in vertebrates

Patients with malignant gastrointestinal disease show high prevalence of malnutrition

Chemical compound provides new angle for developing drugs to treat seizures: Study

Shionogi's CUVPOSA receives FDA approval for treatment of chronic severe drooling

Advanced Protein Systems is now APS BioGroup

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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