Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Researchers discover how statins promote breakdown of plaque in arteries

In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The study was published online by the journal PLoS One on December 6, 2011.

14 Dec 2011

ISIS-FXIRx reduces Factor XI activity without bleeding in healthy volunteers

Isis Pharmaceuticals, Inc. announced today positive results from a Phase 1 study with ISIS-FXIRx. The results demonstrated that treatment with ISIS-FXIRx produced dose-dependent statistically significant reductions of up to 78 percent in Factor XI activity.

13 Dec 2011

Gene therapy for bleeding disorder Hemophilia B

In a landmark study, researchers used gene therapy to successfully treat six patients with severe hemophilia, a blood-clotting disorder. Despite the early nature of the study, it is promising. A single infusion using the new treatment worked in some patients for more than a year, boosting their clotting ability significantly.

12 Dec 2011

Research examines novel treatment techniques for hemophilia B, VTE

Bleeding and clotting disorders affect a large number of patients annually and, while accurate diagnosis is important, timely and effective treatment for these disorders is key, as they have the potential to quickly become life-threatening. Research examining novel treatment techniques for bleeding and clotting disorders will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

12 Dec 2011

FDA panel supports birth control Yaz but advises labeling changes

Medical experts at the panel of Food and Drug Administration have voted 15-11 that Bayer's Yaz, and Yasmin and similar medications used as birth control pills remain a beneficial option for women, despite an increasing number of studies suggesting the drugs are more likely to cause dangerous blood clots than older birth control pills.

11 Dec 2011

FDA panel: Some birth control pills should carry stronger warning labels

An FDA panel decided Thursday that two popular birth control pills should come with stronger warning labels about the possibility of blood clots.

9 Dec 2011

The contraceptive pill could reduce risk of ovarian and uterine cancer in nuns

Professor Roger Short, from the University of Melbourne, and Dr Kara Britt, from Monash University, argue in a comment piece in The Lancet, that since the contraceptive pill reduces overall mortality and mortality specifically linked to ovarian and uterine cancer, nuns should be given the pill for health, rather than contraceptive, reasons.

9 Dec 2011

First Edition: December 9, 2011

Today's early morning highlights from the major news organizations include artilces about a new GOP tax plan that includes a Medicare pay fix for doctors and President Obama's support of a decision to keep the "Morning After Pill" from minors.

9 Dec 2011

VDF, CDC and VDC to educate women about gender-specific DVT risks

Deep vein thrombosis (DVT) is a blood clot in the deep veins in the legs. These clots can break loose and travel to the lungs, causing a potentially fatal pulmonary embolism (PE). Even when they don't, they can cause permanent damage to the leg veins that results in long-term pain, swelling, and disability of the leg.

9 Dec 2011

The Hormone Foundation publishes fact sheet about harmful hCG diet

In an effort to provide clarity to the confusion surrounding the human chorionic gonadotropin (hCG) diet, The Hormone Foundation, the public education affiliate of The Endocrine Society, today published, "Myth vs. Fact: The Human Chorionic Gonadotropin (hCG) Diet."

9 Dec 2011

FDA approves changes to REMS for Nplate and Promacta

The approval of changes to the Risk Evaluation and Mitigation Strategies (REMS) for both Nplate (romiplostim) and Promacta (eltrombopag) was announced by the U.S. Food and Drug Administration.

7 Dec 2011

Leapfrog names UMHHC a top hospital for safety and quality

The University of Michigan hospitals are among the safest and most effective hospitals in the country, according to a new national ranking from the respected independent health care quality rating organization, The Leapfrog Group. This is the second year in a row, and third year overall, that Leapfrog named the U-M Hospitals and Health Centers a top hospital.

7 Dec 2011

New updated site shows how well UMHS provides care in clinical settings

Plenty of hospitals and medical providers claim they do a great job at caring for patients and protecting their safety during care. But very few actually publish the cold, hard numbers that could prove those claims. And even fewer do it like the University of Michigan Health System has: on a website open to anyone, with dozens of charts and graphs showing actual performance and comparisons to national averages and benchmarks.

7 Dec 2011

Scientists regenerate functional muscle tissue in mice

A team of scientists from Worcester Polytechnic Institute (WPI) and CellThera, a private company located in WPI's Life Sciences and Bioengineering Center, have regenerated functional muscle tissue in mice, opening the door for a new clinical therapy to treat people who suffer major muscle trauma.

30 Nov 2011

EC extends therapeutic indication for Soliris to treat atypical hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. today announced that the European Commission (EC) has extended the therapeutic indication for Soliris® (eculizumab) to include the treatment of pediatric and adult patients with atypical hemolytic uremic syndrome (aHUS).

29 Nov 2011

IVC filter study reinforces SIR's guidelines surrounding retrieval or permanent placement

Researchers have published the largest single patient population study to date on a method for following patients with retrievable inferior vena cava (IVC) filters-devices used to keep blood clots from traveling to the lungs.

29 Nov 2011

Most autoimmune diseases associated with increased risk of blood clots on the lung

Autoimmune diseases, in which the immune system attacks the body, are fairly common. Thyroid diseases, type 1 diabetes, rheumatoid arthritis, psoriasis and inflammatory bowel disease are some examples. Autoimmune diseases are associated with increased inflammation in the tissue, which in some cases is linked to an increased propensity to develop clots in the veins.

29 Nov 2011

Just a few drugs responsible for majority of emergency hospitalizations

Latest research shows that just a few drugs are responsible for a majority of the emergency hospitalizations for bad events related to medication use in older U.S. adults.

24 Nov 2011

Cancer medicine component could prevent heart attacks

A substance in medicines for cancer and epilepsy could also prevent heart attacks, according to researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, who have been using it to stimulate the body's own defence system against blood clots.

23 Nov 2011

Study evaluates safety and effectiveness of Diamondback device for heart attacks

Drilling through concrete to create an opening may sound more like construction than medicine, but the approach is similar to what researchers at Orlando Regional Medical Center (ORMC) are doing in a clinical trial to evaluate a device that breaks through hardened coronary arteries, in an effort to prevent heart attacks and relieve chest pain.

23 Nov 2011