Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

St. Jude Medical meets stopping rule in RESPECT clinical trial, closes patient enrollment

St. Jude Medical, Inc., a global medical device company, today announced that it has met a stopping rule in its RESPECT clinical trial - triggered by reaching the protocol-required number of primary events in the trial, defined as stroke and all-cause mortality - and is closing patient enrollment.

4 Jan 2012

Meta-analysis does not find significant association between CYP2C19 genotype and cardiovascular events

Although the U.S. Food and Drug Administration (FDA) has recommended that a certain type of genetic testing (for the genotype CYP2C19) be considered before prescribing the drug clopidogrel to identify individuals who may be less responsive to the medication, a review and analysis of previous studies did not find an overall significant association between the CYP2C19 genotype and cardiovascular events.

28 Dec 2011

New approach may prevent septic shock

Researchers of VIB and UGent have discovered a new approach to preventing septic shock, an often fatal extreme inflammatory reaction of the body. It is the most frequent cause of death at intensive care departments in hospitals.

28 Dec 2011

Survey finds main reasons for resistance to new airport security scanners

Roughly one-quarter of Americans say they would refuse a full body scan using new airport body scanners and 14.9 percent said new airport security measures have them concerned for their health, according to the Thomson Reuters-NPR Health Poll.

26 Dec 2011

Reva Medical commences its first clincial trial

Reva Medical, a medical device company, has today commenced the very first clinical trial of its ReZolve™ bioresorbable coronary stent. A patient in Brazil was implanted with the device overnight, which flags an exciting chapter for Reva Medical.

21 Dec 2011

Enrollment complete in ThromboGenics, BioInvent TB-402 Phase IIb trial on VTE

ThromboGenics NV and co-development partner BioInvent International announce today that they have completed the enrolment of a 632-patient Phase IIb trial with their novel long-acting anticoagulant TB-402 for the prophylaxis of venous thromboembolism (VTE) after total hip surgery. The trial has recruited patients from 36 centers across Europe.

17 Dec 2011

Ten resolutions for healthy aging

Successful aging means more than good health. It means taking charge of your personal wellbeing so that you can continue to live a vibrant, independent life, regardless of your age, according to Dr. Terri Ginsberg of the New Jersey Institute for Successful Aging at the UMDNJ-School of Osteopathic Medicine.

16 Dec 2011

Simple online calculator can tackle pancreatic and bowel cancer

A simple online calculator could offer family GPs a powerful new tool in tackling two of the most deadly forms of cancer, say researchers.

15 Dec 2011

Isis announces addition of three new drug development candidates

Isis Pharmaceuticals, Inc. announced today that it has added three new drugs to its development pipeline, ISIS-APOARx, ISIS-DGAT2Rx and ISIS-FVIIRx.

15 Dec 2011

Researchers discover how statins promote breakdown of plaque in arteries

In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. The study was published online by the journal PLoS One on December 6, 2011.

14 Dec 2011

ISIS-FXIRx reduces Factor XI activity without bleeding in healthy volunteers

Isis Pharmaceuticals, Inc. announced today positive results from a Phase 1 study with ISIS-FXIRx. The results demonstrated that treatment with ISIS-FXIRx produced dose-dependent statistically significant reductions of up to 78 percent in Factor XI activity.

13 Dec 2011

Gene therapy for bleeding disorder Hemophilia B

In a landmark study, researchers used gene therapy to successfully treat six patients with severe hemophilia, a blood-clotting disorder. Despite the early nature of the study, it is promising. A single infusion using the new treatment worked in some patients for more than a year, boosting their clotting ability significantly.

12 Dec 2011

Research examines novel treatment techniques for hemophilia B, VTE

Bleeding and clotting disorders affect a large number of patients annually and, while accurate diagnosis is important, timely and effective treatment for these disorders is key, as they have the potential to quickly become life-threatening. Research examining novel treatment techniques for bleeding and clotting disorders will be presented today at the 53rd Annual Meeting of the American Society of Hematology.

12 Dec 2011

FDA panel supports birth control Yaz but advises labeling changes

Medical experts at the panel of Food and Drug Administration have voted 15-11 that Bayer's Yaz, and Yasmin and similar medications used as birth control pills remain a beneficial option for women, despite an increasing number of studies suggesting the drugs are more likely to cause dangerous blood clots than older birth control pills.

11 Dec 2011

FDA panel: Some birth control pills should carry stronger warning labels

An FDA panel decided Thursday that two popular birth control pills should come with stronger warning labels about the possibility of blood clots.

9 Dec 2011

The contraceptive pill could reduce risk of ovarian and uterine cancer in nuns

Professor Roger Short, from the University of Melbourne, and Dr Kara Britt, from Monash University, argue in a comment piece in The Lancet, that since the contraceptive pill reduces overall mortality and mortality specifically linked to ovarian and uterine cancer, nuns should be given the pill for health, rather than contraceptive, reasons.

9 Dec 2011

First Edition: December 9, 2011

Today's early morning highlights from the major news organizations include artilces about a new GOP tax plan that includes a Medicare pay fix for doctors and President Obama's support of a decision to keep the "Morning After Pill" from minors.

9 Dec 2011

VDF, CDC and VDC to educate women about gender-specific DVT risks

Deep vein thrombosis (DVT) is a blood clot in the deep veins in the legs. These clots can break loose and travel to the lungs, causing a potentially fatal pulmonary embolism (PE). Even when they don't, they can cause permanent damage to the leg veins that results in long-term pain, swelling, and disability of the leg.

9 Dec 2011

The Hormone Foundation publishes fact sheet about harmful hCG diet

In an effort to provide clarity to the confusion surrounding the human chorionic gonadotropin (hCG) diet, The Hormone Foundation, the public education affiliate of The Endocrine Society, today published, "Myth vs. Fact: The Human Chorionic Gonadotropin (hCG) Diet."

9 Dec 2011

FDA approves changes to REMS for Nplate and Promacta

The approval of changes to the Risk Evaluation and Mitigation Strategies (REMS) for both Nplate (romiplostim) and Promacta (eltrombopag) was announced by the U.S. Food and Drug Administration.

7 Dec 2011