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Scientists map epigenetic changes across aging brain cells

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

11 Mar 2026

Viagra ingredient improves symptoms in patients with Leigh syndrome

Sildenafil – an active ingredient also marketed under the name of Viagra – improves symptoms in patients with Leigh syndrome.

11 Mar 2026

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.

11 Mar 2026

Cannabis, cocaine and amphetamines linked to higher stroke risk

Cannabis and other illicit drugs are associated with higher stroke risk, underscoring the importance of addressing substance use disorders in health strategies.

11 Mar 2026

New review reveals complex polygenic architecture underlying common epilepsies

An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide association studies, whole-exome sequencing projects, and advanced statistical modeling to illuminate the polygenic architecture that underpins these heterogeneous neurological disorders.

10 Mar 2026

AI and genetics reveal new insights into human language development

Learning French, reading the latest Andy Weir novel, hanging out with friends for St. Patrick's Day - language is central to all these everyday activities.

10 Mar 2026

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling.

10 Mar 2026

Study links p-tau217 levels to long-term dementia risk in women

Researchers from the University of California San Diego have found that a novel blood-based biomarker can predict a woman's risk of developing dementia as many as 25 years before symptoms appear.

10 Mar 2026

Transposable elements cause majority of lethal mutations in fruit flies

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University.

10 Mar 2026

Targeting IGF2BP2 improves anti-angiogenic therapy effectiveness in colorectal cancer

A recent study published in Engineering has shed light on a novel therapeutic target for improving anti-angiogenic treatment in colorectal cancer (CRC).

10 Mar 2026

How social and environmental exposures across life influence mental health risk

Researchers outline how the exposome framework, which captures the totality of environmental exposures across the lifespan, can help explain how non-genetic factors shape mental health risk and resilience. The perspective highlights how integrating environmental, biological, and social data could improve prevention strategies, research models, and personalized mental health care.

10 Mar 2026

Postbiotics may help treat PCOS by restoring microbiome balance

Emerging studies suggest postbiotics could aid PCOS management by restoring gut microbiome balance and enhancing insulin sensitivity and hormonal regulation.

10 Mar 2026

Adelaide University decodes the secrets of cancer survival

A new study led by researchers at Adelaide University and published in Science Advances has revealed why some cancers can grow and survive in the body, while others cannot.

10 Mar 2026

Using engineered bacteria to breach tumor defenses

Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, Ph.D., FRSC, University Distinguished Professor and chair of the Department of Biology, along with Baylor doctoral students and a colleague at Texas Tech University Health Sciences Center, published their promising research in Cell Chemical Biology.

10 Mar 2026

Enzyme helps maintain retinal progenitor cells during eye development

The retina is a thin layer of neural tissue at the back of the eye that detects light and converts it into signals, sent to the brain.

9 Mar 2026

Long-read whole genome sequencing uncovers new genetic variants linked to autism

Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder (ASD) by using long-read whole genome sequencing (LR-WGS), an emerging approach that reads large sections of the genome at once, making it easier for scientists to find new genetic variants and understand how genetic variants affect the function of a gene.

9 Mar 2026

Largest genetic study classifies 14 psychiatric disorders into five major groups

Although mental disorders have multifactorial causes, genetics can explain some of them, yet this field remains largely unexplored in terms of guiding diagnoses and treatments.

9 Mar 2026

Most pandemic viruses show little adaptation before infecting humans

A new University of California San Diego study published in Cell challenges a long-standing assumption about how animal viruses become capable of sparking human epidemics and pandemics.

9 Mar 2026

AI model flags hidden breast cancers years before diagnosis in routine mammograms

Researchers evaluated four deep learning models using over 112,000 negative screening mammograms from the UK NHS to determine how well artificial intelligence could predict future breast cancers missed during routine screening. The MIT-developed Mirai model performed best, identifying about 27.5% of interval cancers within the top 4% of women flagged as highest risk.

9 Mar 2026