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UCLA study identifies key protein driving kidney scarring

New UCLA research conducted using mouse models and human genetic data has uncovered a critical factor that determines how much scarring occurs following kidney injury, leading scientists to identify a potential precision medicine approach to prevent chronic kidney disease progression.

9 Apr 2025

Gum disease linked to worsening liver health

There is growing recognition in medicine that what happens in one part of the body can ripple through others.

9 Apr 2025

New molecular target identified for pancreatic cancer treatment

Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have identified a new molecular target for treating pancreatic cancer, reports a Gastroenterology study published today.

8 Apr 2025

Tolebrutinib shows promise for treating non-relapsing secondary progressive multiple sclerosis

A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton's tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).

8 Apr 2025

New discovery promises to revolutionize liver organoid development

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods.

8 Apr 2025

AI boosts liver cancer detection by highlighting doubtful areas

A new editorial was published in Oncotarget, Volume 16, on April 4, 2025, titled "Deep learning-based uncertainty quantification for quality assurance in hepatobiliary imaging-based techniques."

8 Apr 2025

Tecan expands portfolio for specialty diagnostics with an asset purchase relating to certain ELISA kits

Tecan Group today announced an agreement to acquire certain assets relating to key ELISA immunoassay products from Cisbio Bioassays SAS, a subsidiary of the global life sciences and diagnostics company, Revvity Inc.

7 Apr 2025

Updated screening protocols could improve early diagnosis of cystic fibrosis

All states should adopt updated screening protocols so more newborns with cystic fibrosis can be diagnosed in the first weeks of life, when interventions can have the greatest benefit, according to the Cystic Fibrosis Foundation guidelines published April 2 in the International Journal of Neonatal Screening.

3 Apr 2025

New thromboinflammation-on-a-chip model may revolutionize treatment of harmful blood clots

Blood clots are associated with life-threatening conditions such as sepsis, sickle cell disease, heart attack, and stroke.

3 Apr 2025

Northwestern scientists develop rapid HIV test for point-of-care diagnosis

A team of Northwestern University scientists spanning disciplines have developed new technology that could lead to the creation of a rapid point-of-care test for HIV infection competitive with traditional lab-based HIV testing in a fraction of the time and without the need for a stressful wait while results are processed or confirmed in a clinical laboratory.

2 Apr 2025

Blood pressure trajectories during early pregnancy can stratify future hypertension risk

NIH-supported study reveals new risk group for future high blood pressure, heart disease.

2 Apr 2025

Fat cells trigger liver stress through secreted lipids

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins.

2 Apr 2025

Survey shows increased awareness of alcohol’s cancer risks

Public awareness of the link between drinking alcohol and an elevated risk of cancer has grown since last fall, with more than half of Americans now saying that regularly consuming alcohol increases your chances of later developing cancer, according to a survey by the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.

1 Apr 2025

Comprehensive AAV delivery map aids in advancing gene therapy

Gene therapy, a technique that is revolutionizing the treatment of multiple genetic conditions, including eye and muscle diseases and blood disorders, requires efficient and specific delivery of the genetic material to the tissue and cell type of interest.

1 Apr 2025

New TIL therapy improves treatment's effectiveness in patients with metastatic gastrointestinal cancers

A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved the treatment's effectiveness in patients with metastatic gastrointestinal cancers, according to results of a clinical trial led by researchers at the National Institutes of Health (NIH).

1 Apr 2025

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat cancer.

31 Mar 2025

Rivaroxaban shown to be a viable alternative to warfarin for left ventricular thrombus

At three months of follow-up, patients hospitalized for a serious heart attack who were treated with the oral blood thinner rivaroxaban for a blood clot in the left ventricle did as well as similar patients who received standard treatment with warfarin, an older blood-thinning drug.

29 Mar 2025

Owlstone Medical secures investment from Cystic Fibrosis Foundation

Owlstone Medical ("Owlstone"), the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced that the Cystic Fibrosis Foundation has made an up to USD $2.3 million equity investment (circa £1.7 million) in Owlstone to develop a breath test for Pseudomonas aeruginosa (PA) detection in patients with cystic fibrosis (CF).

29 Mar 2025

GLDH proposed as a more accurate biomarker for liver injury detection

Researchers from Critical Path Institute's® (C-Path) Predictive Safety Testing Consortium have proposed glutamate dehydrogenase (GLDH) as a more liver-specific biomarker for detecting liver injury, supporting clearer decision-making.

28 Mar 2025

New phospholipids improve functional mRNA delivery via lipid nanoparticles

Researchers develop innovative phospholipids that improve the functional delivery of mRNA via lipid nanoparticles, paving the way for advanced therapeutic applications.

28 Mar 2025