Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

A lifestyle intervention program of increased physical activity, healthy eating and aiming for weight loss of 7% or more, or taking the medication metformin were effective long-term to delay or prevent Type 2 diabetes in adults with prediabetes.

23 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

A review on the hallmarks of cancer and aging

Dr. Mikhail Blagosklonny published his new review paper in Aging (Aging-US) Volume 14, Issue 9, entitled, "Hallmarks of cancer and hallmarks of aging."

18 May 2022

Molecular pathway allows cells to sense when their lipid supplies become depleted

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation.

18 May 2022

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

Clemson researchers discover a promising therapy for people suffering from toxoplasmosis

Many doctors caution their pregnant patients to avoid cat feces; even the family pet's litter box is off-limits. Now, a group of researchers from Clemson University have discovered a promising therapy for those who suffer from toxoplasmosis, a disease caused by the microscopic protozoa Toxoplasma gondii.

11 May 2022

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease.

10 May 2022

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

A research led by Hong Kong University of Science and Technology has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.

9 May 2022

Mitosis in moss plants could be far more similar to animal cell division than previously thought

For a new plant to grow from a seed, cells need to divide numerous times. Daughter cells can each take on different tasks and sometimes vary in size. How plants determine the plane of cell division in this process, known as mitosis, is being researched by Prof. Dr. Ralf Reski and Dr. Elena Kozgunova from the University of Freiburg in a joint effort with Prof. Dr. Gohta Goshima from Nagoya University.

6 May 2022

Crucial discovery could inform potential strategies to control malaria transmission

WEHI researchers in Melbourne have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes.

5 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

CAR-T therapy, a form of immunotherapy that revs up T-cells to recognize and destroy cancer cells, has revolutionized the treatment of blood cancers, including certain leukemias, lymphomas, and most recently, multiple myeloma.

28 Apr 2022

Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology.

26 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Cell division crucial for the success of macrophage infiltration

Researchers at ISTA discover a crucial process that enables immune cells to get to where they are needed. Study published in Science.

21 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils - fibrous, ropelike structures formed by closely linked protein molecules - are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

Molecular Biology News and Research

Further Reading

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A review on the hallmarks of cancer and aging

Molecular pathway allows cells to sense when their lipid supplies become depleted

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

Clemson researchers discover a promising therapy for people suffering from toxoplasmosis

Better understanding of hybrid parasite strains could improve Chagas disease diagnosis

Research opens the door to novel therapies for cancer induced by hedgehog signaling pathway

Mitosis in moss plants could be far more similar to animal cell division than previously thought

Crucial discovery could inform potential strategies to control malaria transmission

Researchers create models to study brain metastases that recapitulate the disease

Black and Hispanic people get the same benefits from CAR-T therapy as white patients

Researchers create 3D in vitro model that reveals the origins of human spine

New discovery about nature’s ‘high-end machinery’ could have big implications for biology

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Cell division crucial for the success of macrophage infiltration

Little-known protein found to play a role in common neurodegenerative disorder

Development of 18 monoclonal antibodies against 9 SARS-CoV-2 proteins

New delivery method enhances the "attack power" of CAR T cells against tumors

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

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