Immune System News and Research

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Wistar scientists discover marker for PMN-MDSCs in the blood of cancer patients

Myeloid-derived suppressor cells (MDSCs) are a population of immune cells that have been implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy.

5 Aug 2016

Disordered airway microbiome at birth may be linked to severe neonatal lung disease

In contrast to the general belief that the airways of an infant are sterile until after birth, University of Alabama at Birmingham researchers and colleagues have found that the infant airway is already colonized with bacteria or bacterial DNA when a baby is born -- and this is true for infants born as early as 24 weeks gestation.

5 Aug 2016

Study demonstrates significant reduction in severity of exercise-induced asthma following B-GOS consumption

Clasado Biosciences Limited, the producers and suppliers of Bimuno(R) (B-GOS), a unique patented trans-galactooligosaccharide complex, today announces the publication of results for the latest clinical study using B-GOS.

5 Aug 2016

Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Tissue injury, such as occurs in response to a lack of oxygen, promotes an influx of immune cells to the site of damage.

5 Aug 2016

Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

A month after announcing that two promising vaccine candidates provided mice with complete protection against the Zika virus, a research team at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research and the University of São Paulo, now reports achieving complete protection against Zika virus in rhesus monkeys.

5 Aug 2016

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

A combination of three medications—dapagliflozin, liraglutide and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Aug 2016

Women using contraception containing estrogen may have high vitamin D levels, study shows

Women risk having their vitamin D levels fall when they stop using birth control pills or other contraceptives containing estrogen, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

4 Aug 2016

New study analyzes evolution of epigenetic mechanisms from bacteria to humans

After the emergence of single-celled organisms some billions of years ago, nature started experimenting with how to diversify gene function without changing the sequence of the DNA, such that the blue print remains conserved, but allows gene products to have different functions.

4 Aug 2016

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Amish farm environment protects children from asthma by shaping immune system

By probing the differences between two farming communities—the Amish of Indiana and the Hutterites of South Dakota—an interdisciplinary team of researchers found that specific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

Lymphoma is a cancer that affects lymphocytes, a type of white blood cell. The disease originates in a lymphoid organ (lymph node, spleen, or bone marrow) before spreading through the blood to infiltrate not only other lymphoid organs but also other tissues.

4 Aug 2016

People with lymphatic filariasis more likely to acquire HIV infection, study shows

People infected with a parasitic worm called Wuchereria bancrofti in areas where HIV is endemic may be more likely to acquire HIV than people who are not infected with the worm, according to a new study in southwest Tanzania, published in The Lancet.

4 Aug 2016

Battling IBD with super heroes: an interview with Dr James Lindsay

Takeda Pharmaceutical Company Limited has launched IBD Unmasked as a first-of-its-kind global initiative designed to raise awareness of the unsung Super Heroes of the global IBD community.

4 Aug 2016

ISU researchers discover protein that appears to predict memory loss, brain atrophy in Alzheimer's patients

Iowa State University researchers have identified a protein essential for building memories that appears to predict the progression of memory loss and brain atrophy in Alzheimer's patients.

4 Aug 2016

Research could provide new insights into finding cure for chronic infections

New research has taken us a step closer to finding a cure for human immunodeficiency virus (HIV), as well as other infections including the glandular fever virus, which is associated with the development of lymphoma.

4 Aug 2016

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched a clinical trial of a vaccine candidate intended to prevent Zika virus infection.

3 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

Neurologists identify cause of immune-mediated neuropathies

Würzburg neurologists have discovered an antibody that is involved in triggering certain forms of neuropathies. This discovery also allowed them to show a way to treat these diseases successfully.

3 Aug 2016

E. coli K1 inhibits glucose transporters during meningitis, report scientists

Escherichia coli K1 (E. coli K1) continues to be a major threat to the health of young infants. Affecting the central nervous system, it causes neonatal meningitis by multiplying in immune cells, such as macrophages, and then disseminating into the bloodstream to subsequently invade the blood-brain barrier.

3 Aug 2016

Immune System News and Research

Wistar scientists discover marker for PMN-MDSCs in the blood of cancer patients

Disordered airway microbiome at birth may be linked to severe neonatal lung disease

Study demonstrates significant reduction in severity of exercise-induced asthma following B-GOS consumption

Heart-resident macrophages promote neutrophil recruitment after ischemic injury

Three vaccine candidates provide complete protection against Zika virus in rhesus monkeys

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

Women using contraception containing estrogen may have high vitamin D levels, study shows

New study analyzes evolution of epigenetic mechanisms from bacteria to humans

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Amish farm environment protects children from asthma by shaping immune system

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Experimental immunotherapeutic strategy may pave way for new treatments against lymphoma

People with lymphatic filariasis more likely to acquire HIV infection, study shows

Battling IBD with super heroes: an interview with Dr James Lindsay

ISU researchers discover protein that appears to predict memory loss, brain atrophy in Alzheimer's patients

Research could provide new insights into finding cure for chronic infections

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

Researchers develop new hybrid method to study HIV protein involved in disease progression

Neurologists identify cause of immune-mediated neuropathies

E. coli K1 inhibits glucose transporters during meningitis, report scientists

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