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Quantification of salivary IgG and IgA against SARS-CoV-2

Salivary antibody levels are many fold lower than found in blood serum, Immunoglobulin G (IgG) in the saliva is mainly sourced from leakage from the gingival surface and Immunoglobulin A (IgA) from mucosal membranes.

15 Sep 2021

UNSW Sydney scientists discover how tiny anchors help the cells to stay in place

Most of the cells in our bodies – be they bone, muscle or pancreas cells – are locked into the right place with the help of tiny anchors.

15 Sep 2021

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Researchers in the United States have developed a new automated approach to detecting variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that have increased growth rates over other lineages.

15 Sep 2021

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

A recent study aimed to use their own classification of different SARS-CoV-2 lineages that would help monitor their genetic features and geographical origins.

14 Sep 2021

Liver may play a key role in the onset or progression of Alzheimer's disease

Amyloid protein made in the liver can cause neurodegeneration in the brain, according to a new study in the open-access journal PLOS Biology, by John Mamo of Curtin University in Bentley, Australia, and colleagues.

14 Sep 2021

Flu shots and COVID-19 immunity

A new paper finds that the influenza vaccine may influence both the response to and incidence of infection by the SARS-CoV-2.

14 Sep 2021

Prior symptomatic COVID-19 enhances mRNA vaccine response

A new paper describes the antibody responses in people who have already been infected with SARS-CoV-2 and are vaccinated as compared to the naïve.

14 Sep 2021

Low dose of Moderna COVID-19 vaccine generates durable immune response

A new study from La Jolla Institute for Immunology (LJI) scientists helps answer the question: how long does immunity against COVID-19 last in vaccinated people?

14 Sep 2021

Study explains confounding effects of different dosages and dosing protocols on COVID-19 vaccine efficacies

A recent study investigates the paradoxical effects of dosage and dosing interval on COVID-19 vaccine efficacy.

14 Sep 2021

Severe COVID-19 linked to increase in autoantibodies

Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies - antibodies directed at their own tissues or at substances their immune cells secrete into the blood - than people without COVID-19, according to a new study.

14 Sep 2021

Gut microbiome can help or confer resistance to weight loss

Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.

14 Sep 2021

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Cholesterol manufactured in the brain appears to play a key role in the development of Alzheimer's disease, new research indicates.

14 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

Progress on treating Alzheimer's disease has been frustratingly slow. A group of scientists in Houston suggest frustration at a very small scale may lead to a new path toward treatment.

14 Sep 2021

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Leading scientists at the University of Birmingham have discovered a previously unknown pathway that prevents specific drugs from working in patients with bowel cancer.

14 Sep 2021

Impact of prior SARS-CoV-2 infection and vaccine on antibody levels: Texas survey

A collaborative team, led by principal investigator Dr. Eric Boerwinkle, at The University of Texas Health Science Center at Houston, School of Public Health is conducting a survey designed to assess the frequency of antibody-positive individuals across Texas. The TEXAS Coronavirus Antibody REsponse Survey (CARES) aims to look for antibodies in the blood made in response to natural SARS-CoV-2 infection or vaccination.

14 Sep 2021

New method for profiling tissue-specific secretory proteins in live mice

Researchers have presented a method for profiling tissue-specific secretory proteins in live mice. This method is expected to be applicable to various tissues or disease models for investigating biomarkers or therapeutic targets involved in disease progression.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Study identifies broadly neutralizing antibody panel against SARS-like viruses

A recent study describes 40 broadly neutralizing antibodies from two individuals with a history of COVID-19 who were recently immunized against the virus.

13 Sep 2021

New SARS-CoV-2 mechanism of host gene suppression

A new study finds that the viral non-coding RNA dubbed vmiR-5p, derived from the viral gene ORF7a, appears to reduce host transcription.

13 Sep 2021

Protein C News and Research

Quantification of salivary IgG and IgA against SARS-CoV-2

UNSW Sydney scientists discover how tiny anchors help the cells to stay in place

New automated approach to detecting SARS-CoV-2 variants with increased growth rates

Study reveals role of globalization and zoonosis in the emergence and spread of SARS-CoV-2 variants

Liver may play a key role in the onset or progression of Alzheimer's disease

Flu shots and COVID-19 immunity

Prior symptomatic COVID-19 enhances mRNA vaccine response

Low dose of Moderna COVID-19 vaccine generates durable immune response

Study explains confounding effects of different dosages and dosing protocols on COVID-19 vaccine efficacies

Severe COVID-19 linked to increase in autoantibodies

Gut microbiome can help or confer resistance to weight loss

Cholesterol appears to play a key role in the development of Alzheimer’s disease

Researchers explore whether cocoa supplementation can reduce aging

Scientists identify a possible “Achilles’ heel” in the frustration of amyloid beta peptides

Researchers discover new pathway that makes drugs less effective in bowel cancer patients

Impact of prior SARS-CoV-2 infection and vaccine on antibody levels: Texas survey

New method for profiling tissue-specific secretory proteins in live mice

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

Study identifies broadly neutralizing antibody panel against SARS-like viruses

New SARS-CoV-2 mechanism of host gene suppression

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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