Immune System News and Research

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Study could offer new ways to enhance cancer immunotherapy

When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties.

4 Jul 2016

Merck partners with University of Nairobi to start medical oncology fellowship program for African doctors

Merck, a leading science and technology company, today announced to start the first Merck Africa Medical Oncology Fellowship Program for Sub-Saharan African countries in partnership with University of Nairobi, Kenya.

4 Jul 2016

New strategy treats fatal autoimmune disease without outward off-target effects

In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists from the Perelman School of Medicine at the University of Pennsylvania have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

4 Jul 2016

Researchers design E. coli-based transport capsule to help fight pneumococcal disease

Most people recoil at the thought of ingesting E. coli. But what if the headline-grabbing bacteria could be used to fight disease?

4 Jul 2016

Researchers develop computer model for speed analysis of TB's complex life-cycle

Tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis, is a serious global health problem accounting for 1.3 million worldwide deaths annually.

1 Jul 2016

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Though a variety of immunotherapy-based strategies are being used against cancer, they are often hindered by the inability of the immune response to enter the immunosuppressive tumor microenvironment and to effectively mount a response to cancer cells.

1 Jul 2016

Implementation science may help prevent mother-to-child HIV transmissions

An emerging field, known as implementation science, may help reduce the nearly 150,000 instances of mother-to-child HIV transmissions that occur annually around the world, mostly in developing countries. c

1 Jul 2016

AHR plays role in modulating the body's innate immune response to viral infections

A receptor, first known for its role in mediating the harmful effects of the environmental pollutant dioxin in our body, is now understood to play other important roles in modulating the innate immune response.

1 Jul 2016

Paracetamol use during pregnancy linked to hyperactivity, autism spectrum symptoms in children

A new study has found that paracetamol (acetaminophen), which is used extensively during pregnancy, has a strong association with autism spectrum symptoms in boys and for both genders in relation to attention-related and hyperactivity symptoms.

1 Jul 2016

SLU researchers receive federal grant to study Zika virus

Saint Louis University vaccine researchers have received $1.3 million in federal funding to study Zika, as part of a multi-site study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

1 Jul 2016

Itaconate can suppress pro-inflammatory activity of macrophages

An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages - specific cells of immune system.

1 Jul 2016

Kataegis linked to better prognosis for breast cancer patients

Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kataegis plays in tumor development and patient outcomes.

1 Jul 2016

Exposure to air pollution may increase risk of kidney disease

While air pollution is known to cause respiratory and cardiovascular diseases, a new study indicates that it also likely causes damage to the kidneys.

30 Jun 2016

Researchers test experimental Zika virus vaccine in mice

An experimental vaccine against Zika virus developed by Brazilian and US researchers has been tested successfully in trials with mice.

30 Jun 2016

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Biofilms are communities of bacteria that adhere to a surface and are nearly impossible to eradicate when they are pathogenic, or disease-causing.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

New IDSA guidelines focus on diagnosis, treatment of deadly aspergillosis

New therapies are improving care, but early diagnosis remains critical in the effective treatment of invasive, a potentially deadly fungal infection, according to new guidelines released by the Infectious Diseases Society of America and published in the journal Clinical Infectious Diseases.

30 Jun 2016

Immunotherapy-treated cancer patients may develop rheumatic disorders

Oncologists need to be aware of the potential for rheumatological diseases in patients with cancer following treatment with immune checkpoint inhibitors, say US investigators.

30 Jun 2016

Stem cell procedure may be safe for ALS patients

A phase II clinical trial in people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, suggests that transplanting human stem cells into the spinal cord may be done safely.

30 Jun 2016

Immune System News and Research

Study could offer new ways to enhance cancer immunotherapy

Merck partners with University of Nairobi to start medical oncology fellowship program for African doctors

New strategy treats fatal autoimmune disease without outward off-target effects

Researchers design E. coli-based transport capsule to help fight pneumococcal disease

Researchers develop computer model for speed analysis of TB's complex life-cycle

Scientists develop new vaccine to stimulate both innate and specific adaptive response

Implementation science may help prevent mother-to-child HIV transmissions

AHR plays role in modulating the body's innate immune response to viral infections

Paracetamol use during pregnancy linked to hyperactivity, autism spectrum symptoms in children

SLU researchers receive federal grant to study Zika virus

Itaconate can suppress pro-inflammatory activity of macrophages

Kataegis linked to better prognosis for breast cancer patients

Exposure to air pollution may increase risk of kidney disease

Researchers test experimental Zika virus vaccine in mice

Novel therapeutic approach may be effective for disrupting bacterial biofilms

Study focuses on critical proteins involved in ovarian cancer biology

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

New IDSA guidelines focus on diagnosis, treatment of deadly aspergillosis

Immunotherapy-treated cancer patients may develop rheumatic disorders

Stem cell procedure may be safe for ALS patients

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