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Cell Therapeutics completes patient enrollment in Phase 3 clinical trial of Opaxio in ovarian cancer

Cell Therapeutics, Inc.today announced that the Gynecologic Oncology Group informed CTI that it has completed patient enrollment in the GOG-0212 Phase 3 clinical trial of investigational agent paclitaxel poliglumex as maintenance therapy in ovarian cancer.

28 Jan 2014

Researchers identify therapeutic target for cervix cancer

Gene related to the proliferation of cancerous cells blocked through molecular technology. A group of researchers from Mexico's General Hospital, Health Secretariat, Medicine Faculty and the Institute of Cellular Physiology of the National Autonomous University of Mexico (UNAM) identified a therapeutic target for cervix cancer: gene CDKN3.

28 Jan 2014

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

St. Jude Children's Research Hospital scientists have discovered a promising new class of antibiotics that could aid efforts to overcome drug-resistance in tuberculosis (TB), a global killer.

28 Jan 2014

Top-line results from two Phase 3 studies of dacomitinib for patients with advanced NSCLC published

Pfizer Inc. today announced top-line results from two randomized Phase 3 studies of the irreversible pan-HER kinase inhibitor dacomitinib in patients with advanced non-small cell lung cancer.

28 Jan 2014

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

BioTime, Inc. and its subsidiary OncoCyte Corporation today announced that OncoCyte has initiated clinical development of its bladder cancer diagnostic test in both the United States and China.

28 Jan 2014

Tufts Medical Center receives funds to develop mathematical models to identify patients for clinical trials

A Tufts Medical Center research team at the Institute for Clinical Research and Health Policy Studies (ICRHPS) has been approved for a funding award by the Patient-Centered Outcomes Research Institute (PCORI) to develop a method for patient-centered enrollment in comparative effectiveness trials called Mathematical Equipoise.

28 Jan 2014

New versions of old antibiotic offers strategy for overcoming drug resistance

Research led by St. Jude Children's Research Hospital scientists has produced new versions of an old antibiotic that are active against difficult-to-treat tuberculosis; offers new strategy for overcoming drug resistance

28 Jan 2014

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Scientists have begun the first human clinical trial of EDP-788, an investigational oral antibiotic intended to treat methicillin-resistant Staphylococcus aureus (MRSA) infections.

27 Jan 2014

Practicing yoga for atleast 3 months can reduce fatigue and inflammation in breast cancer survivors

Practicing yoga for as little as three months can reduce fatigue and lower inflammation in breast cancer survivors, according to new research.

27 Jan 2014

Myelin Repair Foundation enters into agreement with NIH to assess MRF-008 for multiple sclerosis

The Myelin Repair Foundation today announced it has entered a Cooperative Research and Development Agreement with the National Institutes of Health to assess MRF-008, as a potential therapeutic for multiple sclerosis. This CRADA will facilitate collaboration between the MRF and National Institute of Neurological Disorders and Stroke at the NIH Clinical Center to study MRF-008, a drug identified by the MRF as a potential neuroprotective therapeutic to enhance repair in multiple sclerosis patients.

27 Jan 2014

ResearchDx expands operations to focus on Middle East clinical laboratory and diagnostics markets

ResearchDx, LLC of Irvine, California, USA today announced an expansion of its operations to focus on the important Middle East clinical laboratory and diagnostics markets.

27 Jan 2014

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

Novocure announced today that the first patient has enrolled in the EF-20 Study, an open label, pilot clinical trial of NovoTTF Therapy plus gemcitabine as first-line therapy for patients with locally advanced and metastatic pancreatic adenocarcinoma.

25 Jan 2014

Clinical trial of experimental vaccine targets cancer stem cells in patients with recurrent brain tumor

An early-phase clinical trial of an experimental vaccine that targets cancer stem cells in patients with recurrent glioblastoma multiforme, the most common and aggressive malignant brain tumor, has been launched by researchers at Cedars-Sinai's Department of Neurosurgery, Johnnie L. Cochran, Jr. Brain Tumor Center and Department of Neurology.

25 Jan 2014

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

Venaxis, Inc., an in vitro diagnostic company focused on obtaining FDA clearance and commercializing its CE Marked APPY1 Test, a rapid, multiple biomarker-based assay for identifying patients that are at low risk for appendicitis, today announced completion of patient enrollment in its pivotal clinical study of the APPY1 Test in the United States.

24 Jan 2014

TherapeuticsMD starts TX 12-002-HR phase 3 clinical trial for secondary amenorrhea

TherapeuticsMD, Inc., a women's healthcare company, announced today that it has initiated the SPRY Trial, a randomized, placebo-controlled phase 3 clinical trial designed to evaluate the safety and efficacy of TX 12-002-HR, its oral progesterone candidate for secondary amenorrhea, a condition treated to maintain fertility in young premenopausal women.

24 Jan 2014

Moderate radiation doses can kill premalignant cells and prevent second breast cancers

Survivors of breast cancer have a one in six chance of developing breast cancer in the other breast. But a study conducted in mice suggests that survivors can dramatically reduce that risk through treatment with moderate doses of radiation to the unaffected breast at the same time that they receive radiation therapy to their affected breast.

24 Jan 2014

Clinical Trial News and Research

Cell Therapeutics completes patient enrollment in Phase 3 clinical trial of Opaxio in ovarian cancer

Researchers identify therapeutic target for cervix cancer

Scientists produce new version of old antibiotic that is active against difficult-to-treat tuberculosis

Top-line results from two Phase 3 studies of dacomitinib for patients with advanced NSCLC published

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

Tufts Medical Center receives funds to develop mathematical models to identify patients for clinical trials

New versions of old antibiotic offers strategy for overcoming drug resistance

Scientists start clinical trial of EDP-788 oral antibiotic to treat MRSA infections

Practicing yoga for atleast 3 months can reduce fatigue and inflammation in breast cancer survivors

Myelin Repair Foundation enters into agreement with NIH to assess MRF-008 for multiple sclerosis

ResearchDx expands operations to focus on Middle East clinical laboratory and diagnostics markets

First patient enrolled pilot clinical trial of NovoTTF Therapy plus gemcitabine for pancreatic adenocarcinoma

Clinical trial of experimental vaccine targets cancer stem cells in patients with recurrent brain tumor

Patient enrollment completed for Venaxis' pivotal clinical study of APPY1 Test

TherapeuticsMD starts TX 12-002-HR phase 3 clinical trial for secondary amenorrhea

Moderate radiation doses can kill premalignant cells and prevent second breast cancers

American Humane and TGen uncover genetic basis of obsessive-compulsive disorder in dogs

BIDMC receives FDA approval to use new medical device in patients with severely damaged aortic heart valves

Use of twice-daily pill could turn deadly blood cancer into highly treatable disease

BRI receives grant to lead ITN for evaluating novel therapies for transplantation, allergy and autoimmune diseases

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