Biochemistry News and Research

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Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

Researchers in the groups of Prof. Tobias Gulder from TU Dresden and Prof. Tanja Gulder from Leipzig University have succeeded in understanding the biosynthetic mechanisms for the production of the natural product cyanobacterin, which in Nature is produced in small quantities by the cyanobacteria Scytonema hofmanni.

27 May 2022

Researchers identify the genetic causes of three mitochondrial diseases using new approach

When something goes wrong in mitochondria, the tiny organelles that power cells, it can cause a bewildering variety of symptoms such as poor growth, fatigue and weakness, seizures, developmental and cognitive disabilities, and vision problems.

25 May 2022

Dr. Paul Brooks is CN Bio's New Chief Business Officer

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Paul Brooks as Chief Business Officer.

From CN Bio 25 May 2022

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood, publishing their results today in eLife.

24 May 2022

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.

24 May 2022

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

A lifestyle intervention program of increased physical activity, healthy eating and aiming for weight loss of 7% or more, or taking the medication metformin were effective long-term to delay or prevent Type 2 diabetes in adults with prediabetes.

23 May 2022

Plastins may promote disease when they act like workaholics and disrupt cellular environment

A family of proteins that have a role in ensuring many types of cells move and maintain their shape may promote disease when they act like workaholics and disrupt the cellular environment, new research suggests.

19 May 2022

Novel surface treatment could help improve safety of medical devices, prevent hospital infections

A hospital or medical clinic might be the last place you'd expect to pick up a nasty infection, but approximately 1.7 million Americans do each year, resulting in nearly 100,000 deaths from infection-related complications and roughly $30 billion in direct medical costs.

19 May 2022

Epistatic drift leads to unpredictability in protein evolution

A critical goal in genetics and evolution is predicting the effects of mutations that may happen in the future and inferring the effects of those that happened in the past.

19 May 2022

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.

19 May 2022

Researchers test how three mutations work together to produce new SARS-CoV-2 variants

Like storm waves battering a ship, new versions of the SARS-CoV-2 virus have buffeted the world one after another. Recently, scientists keeping tabs on these variants noticed a trend: Many carry the same set of three mutations.

18 May 2022

Origin, evolution and ecological relationships of yeasts

Yeasts have been evolving and diversifying for more than 400 million years. Likely, symbiotic relationships between humans and yeasts started already at the origin of our species (200-300 thousand years ago).

17 May 2022

New discovery has potential to stop inflammation at the "growing end"

Redness, swelling, pain - these are signs of inflammation. It serves to protect the body from pathogens or foreign substances.

13 May 2022

Surprising discovery opens new avenues for in vitro organ culture

How do our cells organize themselves to give their final shape to our organs? The answer lies in morphogenesis, the set of mechanisms that regulate their distribution in space during embryonic development.

13 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

A team of UC Davis researchers has identified a protein in the cancer cell's nucleus as a critical agent keeping Kaposi's sarcoma-associated herpesvirus (KSHV) dormant and undetected by the body's immune system.

11 May 2022

Using virtual reality headsets to instruct UTSA students about protein structures

Francis Yoshimoto, assistant professor in the UTSA College of Sciences' Department of Chemistry, is introducing his Biochemistry II laboratory students to a new way of learning - using virtual reality headsets to observe and analyze protein structures.

10 May 2022

Study uncovers new regulator of prostate cancer metastasis

A transcription factor normally associated with androgen receptor activity in prostate cancer has a newly discovered role in controlling lipid biosynthesis, according to a Northwestern Medicine study published in Nature Genetics.

10 May 2022

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Cells have certain proteins that help them adhere to each other while covering body surfaces and organs. Loss of these identifying proteins could result in cellular progression towards cancer and, subsequently, metastasis.

9 May 2022

Biochemistry News and Research

Researchers gain understanding of biosynthetic mechanisms for producing cyanobacterin

Researchers identify the genetic causes of three mitochondrial diseases using new approach

Dr. Paul Brooks is CN Bio's New Chief Business Officer

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

UH experts in cloning and stem cell science take the first step toward unraveling cystic fibrosis

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

Plastins may promote disease when they act like workaholics and disrupt cellular environment

Novel surface treatment could help improve safety of medical devices, prevent hospital infections

Epistatic drift leads to unpredictability in protein evolution

Potential therapeutic target discovered for pancreatic ductal adenocarcinoma tumors

Researchers test how three mutations work together to produce new SARS-CoV-2 variants

Origin, evolution and ecological relationships of yeasts

New discovery has potential to stop inflammation at the "growing end"

Surprising discovery opens new avenues for in vitro organ culture

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

UC Davis researchers identify a protein that keeps Kaposi's sarcoma-associated herpesvirus dormant

Using virtual reality headsets to instruct UTSA students about protein structures

Study uncovers new regulator of prostate cancer metastasis

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

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