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Study finds growing long-term antipsychotic prescribing in elderly dementia patients

When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people.

16 Jan 2026

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and immune checkpoint inhibitor drugs, but it's not always clear which therapy is inducing what type of response.

16 Jan 2026

Gut microbiota analysis offers insights into how ultra processed foods affect health

To gain more knowledge about how ultra-processed food affects us, we need new research methods, claim researchers. Now they are looking to better understand our intestinal flora.

16 Jan 2026

New review examines the growing global use of melatonin among pediatric populations

Sleep problems are increasingly common among children and adolescents, affecting emotional regulation, cognitive development, and healthy conditions.

16 Jan 2026

Targeting microRNA communication reverses pancreatic cancer's immune suppression

In a unique finding, researchers at Georgetown's Lombardi Comprehensive Cancer Center discovered that when pancreatic cancer cells send out tiny particles that are packed with certain microRNA molecules, nearby immune cells called macrophages are reprogrammed to help the tumor grow instead of engaging in their regular role of fighting the tumor.

16 Jan 2026

AI identifies promising CDK9 inhibitors for cancer treatment

A new and important discovery comes from the field of oncological research thanks to the joint work of researchers from the Sbarro Institute in Philadelphia, the National Cancer Institute – Pascale Foundation, and the University of Pisa.

16 Jan 2026

FDA-cleared ADHD device not effective in reducing symptoms

A large multicenter clinical trial led by King's College London with 150 children and adolescents has shown that a device cleared by the US FDA to treat ADHD is not effective in reducing symptoms.

16 Jan 2026

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

In a Phase 1 clinical study, researchers led by EPFL and their partners report that a new liver- and gut-targeted oral drug can safely lower triglycerides and other blood lipids.

16 Jan 2026

Incretin-based diabetes drugs show potential protective effects against dementia

A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia.

15 Jan 2026

UC San Diego project aims to bioprint patient-specific transplantable human livers

Liver failure is one of the most serious and deadly medical conditions, claiming thousands of lives each year as patients in the United States wait for a donor organ.

14 Jan 2026

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.

14 Jan 2026

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

14 Jan 2026

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

14 Jan 2026

New chemistry revives neurokinin-1 receptor as depression treatment target

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder.

14 Jan 2026

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death.

14 Jan 2026

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.

14 Jan 2026

Bariatric surgery reshapes body fat and muscle more than GLP-1 drugs

Bariatric surgery and GLP-1 treatments reshape body composition differently, emphasizing the importance of sex and treatment choice in muscle preservation.

14 Jan 2026

New mouse model enables study of chronic lung infections in aging

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic diseases, and reduced physiological resilience.

13 Jan 2026

Preclinical study reveals potential new treatment for severe liver fibrosis

Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis - a dangerous, disease-induced build-up of scar tissue in the liver that often leads to cancer.

13 Jan 2026

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Drugs News and Research

Study finds growing long-term antipsychotic prescribing in elderly dementia patients

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Gut microbiota analysis offers insights into how ultra processed foods affect health

New review examines the growing global use of melatonin among pediatric populations

Targeting microRNA communication reverses pancreatic cancer's immune suppression

AI identifies promising CDK9 inhibitors for cancer treatment

FDA-cleared ADHD device not effective in reducing symptoms

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

Incretin-based diabetes drugs show potential protective effects against dementia

UC San Diego project aims to bioprint patient-specific transplantable human livers

MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

New chemistry revives neurokinin-1 receptor as depression treatment target

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Engineered vessels boost retinal organoid function, enabling advanced disease modeling

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Bariatric surgery reshapes body fat and muscle more than GLP-1 drugs

New mouse model enables study of chronic lung infections in aging

Preclinical study reveals potential new treatment for severe liver fibrosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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