Interleukin 2 News and Research

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Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

Study could lead to new strategies to prevent various cancers

Chronic inflammation drives the development of various cancers, including those of the skin, colon and pancreas. Investigators at Massachusetts General Hospital (MGH) who previously demonstrated high expression levels of an immune molecule called interleukin-33 (IL-33) during cancer-promoting inflammation have now uncovered the details behind the molecule's effects.

22 Feb 2021

COVID-19 and lung cancer have a common pathway, say researchers

A new preprint on the bioRxiv* server describes the common features COVID-19 shares with lung cancer.

19 Feb 2021

Endothelial SARS-CoV-2 infection induces proinflammatory responses without supporting viral amplification, finds study

A team of scientists from Australia and Brazil recently investigated the involvement of endothelial cells in the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

18 Feb 2021

New study sheds light on potential pathophysiological mechanism underlying delirium

Delirium, a common syndrome among older adults, particularly in those who have recently undergone surgery, critically ill patients in the ICU, and in older patients with multiple health issues, is a form of acute confusion that is characterized by poor attention, disorientation, impaired memory, delusions, and abrupt changes in mood and behavior.

17 Feb 2021

Immune system directly links personality to long-term mortality risk, study reveals

Ground-breaking research led by University of Limerick has revealed for the first time that the immune system directly links personality to long-term risk of death.

17 Feb 2021

Simulating an overactive autoimmune response leads to changes in the brain region

Researchers at the University of Tsukuba in Japan show that simulating an overactive autoimmune response in mice leads to changes in the hippocampal region of the brain.

17 Feb 2021

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Tumor cells are able to avoid the attack of the immune system through several mechanisms. For instance, these can secrete factors that turn macrophages -cells in the immune system- into dual action agents that contribute to the tumor progress and will protect it from immune body defenses: these become, thus, the tumor-associated macrophages (TAMs).

13 Feb 2021

Study sheds light on the recurrence of herpes simplex virus

Researchers at the University of Virginia School of Medicine have shed light on what causes herpes simplex virus to flare up, explaining how stress, illness and even sunburn can trigger unwanted outbreaks.

12 Feb 2021

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Researchers have measured the galectin-3 levels in the sera of hospitalized patients. They found initial high levels indicate patients will become severely ill, suggesting it could be used as a predictor of severe disease.

10 Feb 2021

Some COVID-19 patients experience persistent chronic fatigue six months after infection, finds study

Scientists from Germany recently revealed that almost 50% of patients present with moderate to severe chronic fatigue syndrome six months after SARS-CoV-2 infection.

10 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Insight into role of aging in response to SARS-CoV-2 infection

Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server medRxiv*.

3 Feb 2021

Immune profiling shows differences in COVID-19 and influenza pathologic pathways

A study conducted at Johns Hopkins University School of Medicine in Baltimore has revealed distinct differences in the immune pathways that are activated by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and those that are activated by influenza.

2 Feb 2021

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Researchers have explored heritable factors, age and body mass on temperature variation between humans. One notable finding is that the current threshold for detecting fever in older adults may be too high, precluding the ability to detect COVID-19 early on

2 Feb 2021

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Working to develop new treatments for osteoarthritis, researchers at Washington University School of Medicine in St. Louis have genetically engineered cartilage to deliver an anti-inflammatory drug in response to activity similar to the bending of a knee or other motions that put stress on joints.

27 Jan 2021

Anakinra shows therapeutic potential in critically ill COVID-19 patients

A team of international scientists recently conducted an open-level clinical trial to investigate the effects of personalized immunotherapy on critically ill COVID-19 patients.

27 Jan 2021

Microglial cells contribute to the negative mood experienced during neurological diseases

Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation.

26 Jan 2021

A traditional Chinese medicine could help treat COVID‐19 symptoms

A team of researchers in China – at Guangzhou University of Chinese Medicine and Yunnan University of Chinese Medicine – recently explored the therapeutic properties of Yinqiao powder in treating COVID-19 symptoms. Their findings were recently published in Phytotherapy Research.

22 Jan 2021

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Interleukin 2 News and Research

Scientists discover mechanism by which epithelial tumors cause maturation defects

Study could lead to new strategies to prevent various cancers

COVID-19 and lung cancer have a common pathway, say researchers

Endothelial SARS-CoV-2 infection induces proinflammatory responses without supporting viral amplification, finds study

New study sheds light on potential pathophysiological mechanism underlying delirium

Immune system directly links personality to long-term mortality risk, study reveals

Simulating an overactive autoimmune response leads to changes in the brain region

Study describes mechanism that limits immunosupressive activity of tumor-associated macrophages

Study sheds light on the recurrence of herpes simplex virus

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Some COVID-19 patients experience persistent chronic fatigue six months after infection, finds study

HIV: New therapeutic approach to restore the effectiveness of immune cells

Insight into role of aging in response to SARS-CoV-2 infection

Immune profiling shows differences in COVID-19 and influenza pathologic pathways

Lower diagnostic threshold for fever in older people may help detect COVID-19 cases earlier

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Anakinra shows therapeutic potential in critically ill COVID-19 patients

Microglial cells contribute to the negative mood experienced during neurological diseases

A traditional Chinese medicine could help treat COVID‐19 symptoms

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

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