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Cleveland Clinic awarded $4.7 million grant to study prevention of cancer-associated blood clots

The National Heart, Lung and Blood Institute (NHLBI), part of the National Institutes of Health, awarded a $4.7 million grant to Cleveland Clinic to study the prevention of life-threatening, cancer-associated blood clots.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

Nanocellulose fibers can reduce fat absorption, research finds

A novel method of reducing the absorption of fat from the gut has recently been granted a US provisional patent. Researchers have demonstrated that the addition of nanocellulose fibres to the food of animals significantly reduces the amount of ingested fat that reaches the bloodstream.

8 Aug 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

3D-printed implants appear to guide regrowth of missing bone in lab animals

Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while "steadily dissolving," researchers report.

2 Aug 2018

Therapy with L-Glutamine reduces pain in patients with sickle cell disease

UCSF Benioff Children's Hospital Oakland clinical researchers, in conjunction with other sickle cell centers and scientists at Emmaus Life Sciences, Inc., have demonstrated that therapy with L-Glutamine reduced the frequency of pain episodes in both pediatric and adult patients with sickle cell disease.

27 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Depression, antidepressant use linked with higher risk of venous thromboembolism

In the first review of its kind, new research has found that depression and the use of antidepressants are each associated with an increased risk of venous thromboembolism.

24 Jul 2018

University of Illinois buys 3D-Bioplotter for regenerative biology, tissue engineering research

The Carl R. Woese Institute for Genomic Biology at the University of Illinois at Urbana-Champaign has purchased an EnvisionTEC 3D-Bioplotter to conduct regenerative biology and tissue engineering research

16 Jul 2018

New study documents symptoms of people before they acquire multiple sclerosis

During the five years before people develop the first clinically recognized signs of multiple sclerosis, they are up to four times more likely to be treated for nervous system disorders such as pain or sleep problems, and are 50 per cent more likely to visit a psychiatrist, according to new research from the University of British Columbia.

16 Jul 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

Inhibiting immune-regulating molecule could prevent or reverse renal injury, research shows

Special cells called podocytes aid the kidneys as they clean the blood and balance the body's fluid levels. Podocytes filter blood as it passes through the cells' foot-like projections they are named for, interwoven like the fingers of clasped hands.

11 Jul 2018

Insight Medical and Onkos Surgical join hands to explore ways to apply augmented reality in musculoskeletal oncology

Insight Medical Systems has teamed up with Onkos Surgical, Inc. to explore opportunities to apply Insight Medical's ARVI in musculoskeletal oncology.

9 Jul 2018

Study offers new hope for people with disabling Dupuytren's disease

Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for progression of Dupuytren's disease.

9 Jul 2018

Graphene could provide better treatment options for osteoarthritis

The intersection of graphene with stem cell biology may one day lead to new treatments for osteoarthritis, say researchers at Boise State University. Impacting millions of people across the globe, osteoarthritis is the most prevalent form of arthritis.

6 Jul 2018

New research project could reduce chance of infection after orthopedic surgery

South Australian researchers are embarking on a $20 million medical and manufacturing research project which could reduce the chance of infection after orthopaedic surgery, thanks to a little help from the humble dragonfly.

2 Jul 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.