Nucleic Acid News and Research

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Scientists develop new method to detect virus presence in cells

Scientists at the Naval Research Laboratory Center for Bio-Molecular Science and Engineering have developed a method to detect the presence of viruses in cells and to study their growth.

12 Apr 2011

Retrovirus XMRV may not be associated with Chronic Fatigue Syndrome in the central nervous system

There has been substantial mystery surrounding the origins of Chronic Fatigue Syndrome (CFS), a condition affecting as many as four million Americans and marked by symptoms that include a sense of weariness that sleep does not improve and difficulty with memory and concentration.

6 Apr 2011

Transgenomic to present study results of high-sensitivity cancer mutation assays at AACR

Transgenomic, Inc. announced today that its scientists have completed studies employing the company's high-sensitivity cancer mutation assays using two proprietary technologies, Ice COLD-PCR and BLOCker-Sequencing. Results from these studies will be presented at the American Association for Cancer Research meeting in Orlando, Florida, April 2-6, 2011.

2 Apr 2011

Transgenomic discovers novel BLOCker-Sequencing technology

Transgenomic, Inc. today announced that it has discovered a novel sequencing technology, which the company has termed BLOCker-Sequencing, which enhances the limit of detection of standard Sanger Sequencing, enriches for direct sequencing of mutated DNA over wild-type and can be run on standard Sanger Sequencing equipment.

30 Mar 2011

Trilink, TATAA sign deal to sell CleanAmp Products

TriLink BioTechnologies, Inc. announced that it has entered into a distribution agreement with TATAA Biocenter to sell its CleanAmp Products.

28 Mar 2011

Biotage introduces new system for microwave-assisted peptide synthesis

Biotage® (STO: BIOT), a supplier of tools and technology for medicinal, analytical and peptide chemistry, introduced the Biotage Initiator Peptide Workstation for manual microwave-assisted peptide synthesis. The Workstation utilizes a unique microwave peptide vial available in two sizes; 2-5 mL for 75-150 μmol scale or 10-20 mL for 250-500 μmol scale synthesis.

24 Mar 2011

CMU's CNAST receives DSF Charitable Foundation grant to develop novel biomedical tools

The DSF Charitable Foundation has given a $3.9 million grant to Carnegie Mellon University's Center for Nucleic Acids Science and Technology to further the development of novel biomedical tools targeted at monitoring and manipulating gene expression.

22 Mar 2011

WaferGen, NuGEN collaborate to develop integrated workflows for gene expression profiling and target enrichment

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genomic analysis systems, and NuGEN Technologies, Inc., a leader in innovative genomic samples preparation, today announced they will co-develop and co-market simple, seamlessly integrated workflows for gene expression profiling and target enrichment to enable researchers to more easily achieve high-throughput, high-density real-time PCR with small, degraded, and hard-to-replace clinical specimens, such as formalin fixed paraffin embedded tissue (FFPE).

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

Idera reports $6.0 million net loss for fourth quarter 2010

Idera Pharmaceuticals, Inc. today reported financial results for the fourth quarter and year ended December 31, 2010.

10 Mar 2011

Santaris licenses miR-33 from MGH to treat cardiovascular disorders

Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the research and development of mRNA and microRNA targeted therapies, today announced that the Company has obtained an exclusive license from Massachusetts General Hospital for intellectual property related to the regulation of miR-33 for the treatment of cardiovascular disorders.

1 Mar 2011

Harvard Medical School selects Agilent's NMR spectrometer for biomolecular research applications

Agilent Technologies Inc. today announced that Harvard Medical School has selected Agilent's 700-MHz Ultra-High Field Nuclear Magnetic Resonance spectrometer for biomolecular research applications.

25 Feb 2011

Covaris, Caliper enter co-marketing agreement to leverage next generation sequencing

Caliper Life Sciences, Inc. and Covaris Inc., Woburn, Mass., today announced a co-marketing agreement which will leverage Covaris' acoustic DNA shearing platforms and Caliper's automation and microfluidics technologies to develop automated workflows for next generation sequencing experiments.

24 Feb 2011

Why are Chlamydia and HPV major public health problems?

Chlamydia trachomatis is a bacterium that is one of the most common sexually transmitted infections in Europe. Rates in sexually active young people are commonly between 5% and 10%. The number of diagnosed cases is increasing in many European countries, in part due to increased testing and the use of more sensitive tests.

22 Feb 2011

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

The Massachusetts General Hospital research team that first discovered tumor-associated RNA in tiny membrane-enclosed sacs released into the bloodstream by cancer cells has now found that these microvesicles also contain segments of tumor DNA, including retrotransposons - also called "jumping genes" - that copy and insert themselves into other areas of the genome.

10 Feb 2011

Phospholipid membranes demonstrate ability to absorb lanthanum cations

University of Granada scientists and the Spanish Higher Institute for Scientific Research (CSIC) have made significant progress in understanding lipid membranes, which are extensively employed in the development of cosmetic and drug products, and which have potential application in the field of nanotechnology.

10 Feb 2011

Akonni signs license agreement with USAMRIID to develop multiplex testing products for bio-security applications

Akonni Biosystems, a molecular diagnostics (MDx) company that develops rapid, low-cost and highly scalable solutions for infectious disease testing, today announced it has signed a license agreement with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID).

10 Feb 2011

Roche launches cobas TaqScreen DPX Test for parvovirus B19 and hepatitis A virus

Roche announced today that the cobas® TaqScreen DPX Test for use on the cobas s 201 system is now available in the US. It is the first commercial test to quantify parvovirus B19 and detect hepatitis A virus (HAV) simultaneously in one assay in human plasma.

5 Feb 2011

Nitto Denko announces acquisition of Avecia Biotechnology

Japan's leading diversified materials manufacturer, Nitto Denko Corporation, today announced that it has acquired Avecia Biotechnology, Inc. through Nitto Americas, Inc., a wholly owned subsidiary in Teaneck, New Jersey.

3 Feb 2011

Automation protocols for TruSeq kits is now available in Sciclone NGS Workstation

Caliper Life Sciences, today announced that it has developed and optimized automation protocols on its Sciclone NGS Workstation for Illumina's TruSeq DNA and TruSeq RNA sample preparation kits.

3 Feb 2011

Nucleic Acid News and Research

Scientists develop new method to detect virus presence in cells

Retrovirus XMRV may not be associated with Chronic Fatigue Syndrome in the central nervous system

Transgenomic to present study results of high-sensitivity cancer mutation assays at AACR

Transgenomic discovers novel BLOCker-Sequencing technology

Trilink, TATAA sign deal to sell CleanAmp Products

Biotage introduces new system for microwave-assisted peptide synthesis

CMU's CNAST receives DSF Charitable Foundation grant to develop novel biomedical tools

WaferGen, NuGEN collaborate to develop integrated workflows for gene expression profiling and target enrichment

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

Idera reports $6.0 million net loss for fourth quarter 2010

Santaris licenses miR-33 from MGH to treat cardiovascular disorders

Harvard Medical School selects Agilent's NMR spectrometer for biomolecular research applications

Covaris, Caliper enter co-marketing agreement to leverage next generation sequencing

Why are Chlamydia and HPV major public health problems?

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

Phospholipid membranes demonstrate ability to absorb lanthanum cations

Akonni signs license agreement with USAMRIID to develop multiplex testing products for bio-security applications

Roche launches cobas TaqScreen DPX Test for parvovirus B19 and hepatitis A virus

Nitto Denko announces acquisition of Avecia Biotechnology

Automation protocols for TruSeq kits is now available in Sciclone NGS Workstation

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