Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Researchers uncover immune system barrier to cancer treatment

By recruiting the immune system to combat tumor cells, immunotherapy has improved survival rates, offering hope to millions of cancer patients. However, only about one in five people responds favorably to these treatments.

7 Aug 2024

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

A study in Nature Neuroscience found that both neurons and oligodendrocytes contribute to amyloid-β plaque burden in Alzheimer's disease, highlighting new therapeutic targets.

7 Aug 2024

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.

6 Aug 2024

AI model matches radiologists in detecting clinically significant prostate cancer on MRI

A deep learning model performs at the level of an abdominal radiologist in the detection of clinically significant prostate cancer on MRI, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

6 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

In an effort to combat one of the most lethal forms of pediatric brain cancer, researchers at the UCLA Health Jonsson Comprehensive Cancer Center are launching a first-of-its-kind clinical trial to evaluate the safety and effectiveness of a cancer vaccine targeting H3 G34-mutant diffuse hemispheric glioma, a highly aggressive brain tumor that is typically found in adolescents and young adults.

5 Aug 2024

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Research highlights how cholesterol imbalances in the brain contribute to neurodegenerative diseases like Alzheimer's, Huntington's, and Parkinson's, suggesting targeted therapeutic interventions.

5 Aug 2024

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

A new study has shown that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with more than fourfold higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years of delivery.

2 Aug 2024

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Scientists at St. Jude Children's Research Hospital have created a panel that is able to provide a diagnosis for >90% of pediatric cancer patients by sequencing 0.15% of the human genome.

1 Aug 2024

Oropouche virus: Emerging threats and unanswered questions

Announcing a new article publication for Zoonoses journal. Oropouche virus (genus Orthobunyavirus, family Peribunyaviridae) is an arthropod-borne virus that infects several species of animals and humans, primarily in South America.

1 Aug 2024

Nasal COVID-19 vaccine shows promise in preventing virus spread

The lightning-fast development of COVID-19 vaccines just months after the virus appeared was a triumph of modern science and saved millions of lives.

31 Jul 2024

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Early detection of Alzheimer's disease-related changes in Parkinson's disease and dementia with Lewy bodies could be made possible by monitoring the amyloid-β (Aβ) and phosphorylated tau (p-tau) proteins.

31 Jul 2024

Targeting oncogenic transcription factors to develop potential new cancer treatments

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin.

30 Jul 2024

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways.

30 Jul 2024

Spatial patterns of cortical microstructural change can be early indicators of Alzheimer's disease risk

Findings from a novel study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, published by Elsevier, suggest that using a specialized diffusion weighted MRI scan to monitor the spatial pattern of individual cortical microstructural change in the brain may be a promising approach to characterize individuals who may be vulnerable to developing Alzheimer's disease (AD) prior to significant cognitive decline and irreversible neuronal damage.

30 Jul 2024

Study finds plasma biomarkers can predict dementia risk

A study in JAMA explores the potential of plasma biomarkers for Alzheimer’s disease and cardiometabolic risk factors to predict other types of dementia, highlighting the importance of early diagnosis and combining biomarkers with demographic data for improved accuracy.

30 Jul 2024

Pathology News and Research

Further Reading

Researchers uncover immune system barrier to cancer treatment

Study uncovers roles of certain brain cells in Alzheimer's plaque formation

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

AI model matches radiologists in detecting clinically significant prostate cancer on MRI

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

UCLA launches groundbreaking clinical trial for vaccine targeting aggressive pediatric brain cancer

Cholesterol imbalance linked to neurodegeneration, study suggests potential strategies for intervention

Study finds fourfold increase in risk of overt hypothyroidism after diagnosis of gestational subclinical hypothyroidism

St. Jude develops cost-effective genetic panel for pediatric cancer diagnosis

Oropouche virus: Emerging threats and unanswered questions

Nasal COVID-19 vaccine shows promise in preventing virus spread

Neurofilament light chain identified as early marker for Parkinson’s and dementia with Lewy Bodies

Targeting oncogenic transcription factors to develop potential new cancer treatments

Review highlights the interplay of TGF-β and HIPPO pathways in liver regeneration and disease

Spatial patterns of cortical microstructural change can be early indicators of Alzheimer's disease risk

Study finds plasma biomarkers can predict dementia risk

ACE technology enhances single-cell protein detection with advanced signal amplification

New prognostic marker identified for gastric cancer recurrence risk

Study reveals IL-22BP protein's role in gut health and infection resistance

New blood test achieves 90% accuracy in diagnosing Alzheimer’s disease, outperforms doctors

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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