Peptides News and Research

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Neuropilin-1: A new route of SARS-CoV-2 entry

A new study published in the reputed journal Science in October 2020 reports the potential therapeutic value of the second type of host transmembrane receptor, called neuropilins, which attach to the spike protein of SARS-CoV-2 and may enhance its infectivity.

25 Oct 2020

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Our immune system's capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65.

20 Oct 2020

Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

A combination of peptides and antibiotics could be key to eliminating the parasite causing leishmaniasis and avoiding the toxicity to people and animals caused by current drugs.

16 Oct 2020

Combination of antibiotics and peptides could eliminate parasite-causing leishmaniasis

A combination of peptides and antibiotics could be key to eliminating the parasite causing leishmaniasis and avoiding the toxicity to people and animals caused by current drugs.

16 Oct 2020

Scientists engineer powerful novel anti-microbial molecules from wasp venom

Now, a team of scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered potent novel anti-microbial molecules from toxic proteins found in wasp venom. The researchers believe that the discovery holds promise in fighting the increasing number of antibiotic-resistant bacteria, that cause serious illness.

15 Oct 2020

GIV protein involved in the immune system could form basis for novel therapeutics

The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.

15 Oct 2020

Integrin b3 and ACE2 linked by short linear motifs enabling endocytosis and autophagy of SARS-CoV-2

A new study by Uppsala University researchers published on the preprint server bioRxiv in October 2020 shows possible links between the angiotensin-converting enzyme 2 (ACE2) host cell receptors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the entry of viral particles into the cell via endocytosis and autophagy.

12 Oct 2020

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

12 Oct 2020

Scientists develop new type of precise therapeutic vaccine against leukemia

Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.

12 Oct 2020

New drug delivery systems can improve treatment for diseases that affect connective tissues

University of Delaware Professor Kristi Kiick is leading collaborative research to create new drug delivery systems with the potential to improve treatment for diseases that affect connective tissues, such as osteoarthritis or rheumatoid arthritis, which is an autoimmune disease.

9 Oct 2020

Researchers discover a new, rapid method to fabricate nanoparticles

Northwestern University researchers are casting a net for nanoparticles.The team has discovered a new, rapid method for fabricating nanoparticles from a simple, self-assembling polymer.

6 Oct 2020

New findings could improve investigation of T cell response to COVID-19

Researchers in the United States have made an important discovery about the processing and presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral peptides that provides a better understanding of the immune response to coronavirus disease 2019 (COVID-19) and may help facilitate the design of improved vaccines.

5 Oct 2020

Study confirms SARS-CoV-2 spike glycoprotein promotes a hyper-inflammatory immune response

A group of researchers from Australia and China recently demonstrated how SARS-CoV-2 spike glycoprotein subunit 1 can induce a pro-inflammatory signaling pathway (leading to cytokines deployment and epithelial damage in human bronchial epithelial cells), but also highlighted the potential of peptide-based antivirals in tackling this novel coronavirus.

5 Oct 2020

Advanced model reveals dynamic motions of SARS-COV-2 spike-shielding glycans

A recent paper published on the preprint server bioRxiv in September 2020 discusses the dynamic interactions of the spike protein glycan shield, which may be of great value in developing therapeutic compounds to fight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

5 Oct 2020

New approach transforms oldest antibiotics into safer, stronger drugs

Physicians and scientists have long searched the natural world for chemicals that can improve human health. However, evolutionary selection optimized natural chemicals to benefit their host, not for safety or efficacy in humans.

5 Oct 2020

Discovery of high affinity binders for SARS-CoV-2 spike protein

An exciting, 'tour-de-force' paper by researchers from the Massachusetts Institute of Technology describes de novo discovery of high-affinity peptide binders for SARS-CoV-2 spike glycoprotein, which opens the door for the development of rapid viral identification or conjugates for virus-directed delivery of therapeutics.

30 Sep 2020

Researchers identify a new method to produce miniaturized antibodies

Researchers at the University of Bath in the UK and biopharma company UCB have found a way to produce miniaturized antibodies, opening the way for a potential new class of treatments for diseases.

30 Sep 2020

Using new technology to study antibody responses in SARS-CoV-2-infected individuals

Using a technology called VirScan to study coronavirus antibody responses in a large cohort of SARS-CoV-2-infected and control individuals, researchers identified epitopes recognized by a large fraction of COVID-19 patients, epitopes cross-reactive with antibodies developed in response to other human coronaviruses, and 10 epitopes likely recognized by neutralizing antibodies.

29 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

UNH awarded $1.8 million NIH grant to advance molecular research in diabetes and cancer

The University of New Hampshire will receive $1.8 million from the National Institutes of Health that will further molecular research to better understand drug interactions at the cellular level and help lead to the development of new targeted drugs to treat wide-spread metabolic, growth, neurological and visual disorders including diabetes and cancer.

24 Sep 2020

Peptides News and Research

Neuropilin-1: A new route of SARS-CoV-2 entry

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

Combination of antibiotics and peptides could eliminate parasite-causing leishmaniasis

Scientists engineer powerful novel anti-microbial molecules from wasp venom

GIV protein involved in the immune system could form basis for novel therapeutics

Integrin b3 and ACE2 linked by short linear motifs enabling endocytosis and autophagy of SARS-CoV-2

Powerful antimicrobial molecules engineered from toxic proteins in wasp venom

Scientists develop new type of precise therapeutic vaccine against leukemia

New drug delivery systems can improve treatment for diseases that affect connective tissues

Researchers discover a new, rapid method to fabricate nanoparticles

New findings could improve investigation of T cell response to COVID-19

Study confirms SARS-CoV-2 spike glycoprotein promotes a hyper-inflammatory immune response

Advanced model reveals dynamic motions of SARS-COV-2 spike-shielding glycans

New approach transforms oldest antibiotics into safer, stronger drugs

Discovery of high affinity binders for SARS-CoV-2 spike protein

Researchers identify a new method to produce miniaturized antibodies

Using new technology to study antibody responses in SARS-CoV-2-infected individuals

Induction of acute senescence may be a necessary process in hemorrhagic shock

UNH awarded $1.8 million NIH grant to advance molecular research in diabetes and cancer

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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