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NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

A new study explores the role of non-structural protein 1 (NSP1) in SARS-CoV-2 infection and pathogenesis.

16 Jun 2022

Researchers uncover how dopamine in the cerebellum modulates social behaviors

The cerebellum is essential for sensorimotor control but also contributes to higher cognitive functions including social behaviors.

16 Jun 2022

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Most skin cancer drugs that activate the immune system work by triggering immune cells, called T cells, to attack tumors, but when T cells are activated for too long, they can wear out and cease to function.

16 Jun 2022

Four interdisciplinary teams will receive $100 million to solve the toughest challenges in cancer research

The Cancer Grand Challenges program will award $100 million to four interdisciplinary teams from around the world to solve some of the toughest challenges in cancer research.

16 Jun 2022

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Researchers assessed the efficiency of a hybrid vaccine against influenza and COVID-19 viruses.

16 Jun 2022

New component of cell death process could play key role in infection-fighting strategy

Researchers have unmasked a component of the cell death process that could play a vital role in a better infection-fighting strategy.

16 Jun 2022

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers found that immune-boosting by SARS-CoV-2 Omicron variant is contingent on prior COVID-19 history.

16 Jun 2022

Researchers evaluate artemisinin for COVID-19 management

Researchers assessed the effectiveness of artemisinin-based antimalarials in the management of COVID-19.

16 Jun 2022

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

In a recent study posted to the bioRxiv* pre-print server, researchers illustrated the cryo-electron microscopic (cryo-EM) structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein in lipid nanodiscs to 3.5 angstroms (Å) resolution.

16 Jun 2022

Moffitt researchers reveal a mechanism leading to drug resistance in prostate cancer

Prostate cancer is the most common cancer among men in the United States. Many patients can live long lives due to early detection and treatment with androgen deprivation therapy.

16 Jun 2022

Multiomics identifies genomic risk factors for COVID-19

In a recent Cell Systems study, researchers utilized the RefMap machine learning algorithm to correlate known genomic variations for severe COVID-19 obtained from large-scale genome-wide association studies (GWAS) with single-cell multiome profiling of human lungs.

16 Jun 2022

Chemical synthesis, properties, and molecular modeling studies of spiro-indole compounds

In a recent study under review at the Scientific Reports journal and currently posted to the Research Square* preprint server, researchers synthesized and evaluated the antitumoral (against several cancer cell lines) and antiviral [against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] properties of 3-spiro-indolin-2-ones.

15 Jun 2022

Researchers create first bona fide mouse model of Merkel cell carcinoma

A team of researchers at the University of Michigan Rogel Cancer Center were the first to generate a bona fide mouse model of a Merkel cell carcinoma, a rare and potentially aggressive form of skin cancer.

15 Jun 2022

SARS-CoV-2 damages cilia

Researchers determine whether the interaction between ORF10 and ZYG11B promotes the dissemination of SARS-CoV-2.

15 Jun 2022

Drug combinations may help to slow the progression of diabetic kidney disease

A mouse study led by Washington University School of Medicine in St. Louis suggests that combining SGLT2 inhibitors — a newer class of diabetes medications that lowers blood sugar — with older diabetes drugs may help to slow the progression of diabetic kidney disease.

15 Jun 2022

More than 1,000 genes linked to severe COVID-19 identified

Since the start of the coronavirus pandemic, scientists and clinicians have struggled to understand why some people with the infection become seriously ill or die while others have few, if any, symptoms.

15 Jun 2022

Cellular "barcoding" in mice unravels the origins of blood

The origins of our blood may not be quite what we thought. Using cellular "barcoding" in mice, a groundbreaking study finds that blood cells originate not from one type of mother cell, but two, with potential implications for blood cancers, bone marrow transplant, and immunology. Fernando Camargo, PhD, of the Stem Cell Program at Boston Children's Hospital led the study, published in Nature on June 15.

15 Jun 2022

Research reveals a potential Achilles heel in the protective layers surrounding Gram-negative bacteria

A new study published in Nature today has identified a potential Achilles heel in the protective layers surrounding Gram-negative bacteria that could aid in the development of next-generation antibiotics.

15 Jun 2022

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

A newly developed test could help doctors more accurately predict whether individuals who undergo gastric bypass surgery will experience a remission of type 2 diabetes within two years of the procedure, according to University of Utah Health scientists.

15 Jun 2022

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

B Cell News and Research

NSP1 found to act as an immune evasion factor in SARS-CoV-2 infections

Researchers uncover how dopamine in the cerebellum modulates social behaviors

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Four interdisciplinary teams will receive $100 million to solve the toughest challenges in cancer research

Effectiveness of a hybrid vaccine against COVID-19 and influenza

New component of cell death process could play key role in infection-fighting strategy

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers evaluate artemisinin for COVID-19 management

Cryo-electron microscopy structure of SARS-CoV-2 membrane protein

Moffitt researchers reveal a mechanism leading to drug resistance in prostate cancer

Multiomics identifies genomic risk factors for COVID-19

Chemical synthesis, properties, and molecular modeling studies of spiro-indole compounds

Researchers create first bona fide mouse model of Merkel cell carcinoma

SARS-CoV-2 damages cilia

Drug combinations may help to slow the progression of diabetic kidney disease

More than 1,000 genes linked to severe COVID-19 identified

Cellular "barcoding" in mice unravels the origins of blood

Research reveals a potential Achilles heel in the protective layers surrounding Gram-negative bacteria

Blood levels of ceramides could help predict type 2 diabetes remission after gastric bypass surgery

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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