Therapy News and Research

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An integrated approach could pave the way for future control of Alzheimer's disease

This new pioneering study by Prof. Ricardo Maccioni and coworkers of the International Center for Biomedicine, "New Frontiers in the prevention, diagnosis and treatment of Alzheimer´s disease" was published in the special issue of Latin American investigators of the Journal of Alzheimer's Disease.

1 Feb 2021

New WHO guidelines provide recommendations for managing chronic pain in children

Chronic pain or pain that persists or recurs for longer than three months in children is a significant public health problem and a leading cause of morbidity in children globally.

1 Feb 2021

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

1 Feb 2021

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

A new £1.7m project to explore using plasma jets and antimicrobial dressings to treat debilitating - and potentially deadly - wound infections launches today.

1 Feb 2021

Study finds high bleeding risk in a sub-group of COVID-19 patients

The human body strives to keep itself in homeostasis, or balance. When blood clots are created, the body's innate response is to break the clots down to prevent significant health problems from arising.

1 Feb 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

(Primary analysis of the Lung Cancer Mutation Consortium (LCMC) 3 study revealed that neoadjuvant atezolizumab prior to lung cancer surgery was well tolerated by patients and met its primary endpoint of 20% major pathologic response rate, according to research presented today at the International Association for the Study of Lung Cancer's World Conference on Lung Cancer.

31 Jan 2021

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).

31 Jan 2021

UC Riverside mouse study resolves long-standing mystery by a whisker

When we step on the car brake upon seeing a red traffic light ahead, a sequence of events unfolds in the brain at lightning speed.

30 Jan 2021

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that the independent Data Safety Monitoring Board (DSMB) for the global Phase 2/3 study of opaganib in patients with severe COVID-19, unanimously recommended to continue the study following a pre-scheduled futility review of unblinded efficacy data from the first 135 patients treated in the study and safety data from the first 175 patients.

30 Jan 2021

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies.

29 Jan 2021

Robotic exoskeleton gait training may aid early rehabilitation for stroke

A team of New Jersey researchers has demonstrated that high-dose therapy gait training using robotic exoskeletons may aid early rehabilitation for acute stroke.

29 Jan 2021

New gene-based vaccine strategy receives grant from the Bill & Melinda Gates Foundation

The AAVCOVID vaccine program, a novel gene-based vaccine strategy that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation.

29 Jan 2021

Thread-based sensors can measure head movements in real time

Engineers at Tufts University have created and demonstrated flexible thread-based sensors that can measure movement of the neck, providing data on the direction, angle of rotation and degree of displacement of the head.

29 Jan 2021

SORLA protein promotes the growth of breast cancer brain metastasis

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells.

29 Jan 2021

Kids already coping with mental disorders spiral as pandemic topples vital support systems

A bag of Doritos, that’s all Princess wanted. Her mom calls her Princess, but her real name is Lindsey. She’s 17 and lives with her mom, Sandra, a nurse, outside Atlanta.

29 Jan 2021

Scientists create new way to detect COVID-19 proteins and antibodies

Scientists have created a new way to detect the proteins that make up the pandemic coronavirus, as well as antibodies against it. They designed protein-based biosensors that glow when mixed with components of the virus or specific COVID-19 antibodies.

29 Jan 2021

Study: Targeting glycoprotein could improve response to cancer immunotherapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

28 Jan 2021

Physicians receive Pfizer Prize for research on leukemia, cardiac arrhythmias

This year, four of a total of fifteen Pfizer Research Prizes have been awarded to physicians from the University of Bern and the Inselspital, University Hospital Bern.

28 Jan 2021

Therapy News and Research

An integrated approach could pave the way for future control of Alzheimer's disease

New WHO guidelines provide recommendations for managing chronic pain in children

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

Study finds high bleeding risk in a sub-group of COVID-19 patients

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

UC Riverside mouse study resolves long-standing mystery by a whisker

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

RPS-12 protein overproduction appears to trigger breast cancer and other malignancies

Robotic exoskeleton gait training may aid early rehabilitation for stroke

New gene-based vaccine strategy receives grant from the Bill & Melinda Gates Foundation

Thread-based sensors can measure head movements in real time

SORLA protein promotes the growth of breast cancer brain metastasis

Kids already coping with mental disorders spiral as pandemic topples vital support systems

Scientists create new way to detect COVID-19 proteins and antibodies

Study: Targeting glycoprotein could improve response to cancer immunotherapy

Physicians receive Pfizer Prize for research on leukemia, cardiac arrhythmias

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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