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COVID-19 booster shot in autumn will effectively protect against existing and future variants

Scientists at the University of Nottingham have confirmed that an autumn 'booster' dose of a Covid-19 vaccine will be an effective way to protect people from existing, and potentially future, variants of concern.

11 Aug 2021

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Scientists from Germany and Belgium have recently described the immunogenicity of a plant-based virus-like particle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vaccine induces robust antibody and T cell responses for at least 6 months. Moreover, the vaccine demonstrates potent neutralizing efficacy against the B.1.1.7, B.1.351, and P1 variants of SARS-CoV-2.

11 Aug 2021

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

A new study explores the polyclonal antibody response to SARS-CoV-2 in greater detail.

10 Aug 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

Natural vs. vaccine-induced COVID-19 immunity

A new paper discusses the protection offered by immunity against COVID-19 following vaccination as compared to natural infection.

10 Aug 2021

IMBA researchers may have found the "Achilles' heel" of SARS-CoV-2 virus

Researchers identify two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants.

10 Aug 2021

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

A potential new treatment for mast cell cancers reduces the number of mast cells by "mutating" the messenger RNA (mRNA) before it can deliver instructions for manufacturing the gene responsible for cell proliferation.

10 Aug 2021

New platform can quickly identify common mutations on the SARS-CoV-2 virus

Researchers at the University of Colorado Boulder have developed a platform which can quickly identify common mutations on the SARS-CoV-2 virus that allow it to escape antibodies and infect cells.

10 Aug 2021

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

A University of South Florida preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema.

10 Aug 2021

New approach could be a useful tool in the fight against cancer drug resistance

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

10 Aug 2021

Study reveals the trends in consumption of ultraprocessed foods among children and adolescents

The calories that children and adolescents consumed from ultraprocessed foods jumped from 61% to 67% of total caloric intake from 1999 to 2018, according to a new study from researchers at the Friedman School of Nutrition Science & Policy at Tufts University.

10 Aug 2021

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

In new research, scientists evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the remdesivir parent nucleoside (GS-441524) against viruses that cause diseases of human public health concern, including SARS-CoV-2.

10 Aug 2021

SARS-CoV-2 variants and their ability to infect mice

A new study published on the bioRxiv* preprint server has conducted in silico studies along with in vitro, in vivo, and in situ observations and indicated the mouse adaptation of SARS-CoV-2.

10 Aug 2021

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

A recent study in Colorado used real-world data to evaluate if individuals with chronic conditions have reduced antibody response to COVID-19 mRNA vaccines. The study investigated whether some medical conditions may impact antibody response to the mRNA vaccines.

9 Aug 2021

PTEN nuclear translocation plays a key role in neuronal injury following hypoxia-ischemia

Aging-US published "PTEN nuclear translocation enhances neuronal injury after hypoxia-ischemia via modulation of the nuclear factor-κB signaling pathway" which reported that this study was designed to investigate phosphatase and tensin homolog nuclear translocation and its possible role in rat cortical neuronal damage following oxygen-glucose deprivation in vitro.

9 Aug 2021

Protein C News and Research

COVID-19 booster shot in autumn will effectively protect against existing and future variants

Plant-based virus-like particle vaccine induces durable immune response against SARS-CoV-2 variants

Study defines SARS-CoV-2 antibodies associated with neutralization and effector functions

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

Natural vs. vaccine-induced COVID-19 immunity

IMBA researchers may have found the "Achilles' heel" of SARS-CoV-2 virus

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

New platform can quickly identify common mutations on the SARS-CoV-2 virus

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

New approach could be a useful tool in the fight against cancer drug resistance

Study reveals the trends in consumption of ultraprocessed foods among children and adolescents

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

SARS-CoV-2 variants and their ability to infect mice

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

PTEN nuclear translocation plays a key role in neuronal injury following hypoxia-ischemia

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

New biocompatible glue could quickly seal injured tissues and stop bleeding

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

Dileucine more effective than leucine in stimulating muscle-building in humans

Researchers bind anti-bacterial molecules with graphene to destroy bacteria on implants

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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