Immune System News and Research

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ITJ researchers develop new hydrating beverage for athletes

Jiquiquilpan's Institute of Technology in Mexico developed a hydrating beverage for athletes that is based on agave's fructans, that not only supplies the adequate water levels to the organisms, but also offers other benefits such as dietetic fiber.

5 May 2016

Enzyme previously thought beneficial could pose threat to developing embryos

A pair of Oklahoma Medical Research Foundation scientists have discovered that an enzyme previously thought only to be beneficial could, in fact, pose significant danger to developing embryos. The new research could have implications not only for prenatal development but also for treating lymphedema and liver damage resulting from acetaminophen overdose.

5 May 2016

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

Early viral respiratory infections may increase type 1 diabetes risk in children

Viral respiratory infections during the first six months of life are associated with an increased risk for type 1 diabetes. This is the conclusion reached by a team of scientists at the Helmholtz Zentrum München during a study published in the current issue of the renowned US magazine 'JAMA'.

5 May 2016

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall.

5 May 2016

Human milk hormones may play vital role in shaping healthy infant microbiome

A new University of Colorado Anschutz Medical Campus study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

5 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Respiratory tract infection in infants linked with increased T1D risk

In a study appearing in the May 3, 2016 issue of JAMA, Anette-Gabriele Ziegler, M.D., of Helmholtz Zentrum Munchen, Munich, Germany, and colleagues examined associations between infection types during the first 2 years of life and between respiratory tract infections in the first 6 months and type l diabetes (T1D). Viral infections, particularly enteroviruses, have been hypothesized to cause T1D. Recent studies suggest that respiratory tract infections are associated with increased T1D risk if they are encountered within the first 6 months.

4 May 2016

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.

4 May 2016

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs.

4 May 2016

New study links cathepsin S protein to tear secretion in Sjogren's syndrome patients

The autoimmune disorder Sjogren's syndrome is often overlooked or misdiagnosed because the symptoms are similar to other conditions. Its characteristic symptoms are dry eyes and dry mouth, and reduced tear production is used as part of the diagnosis.

4 May 2016

Ebola vaccine shows promise in clinical trials

"The results for tolerability, safety, and the immune response to the vaccine candidate are very promising," explains Prof Marylyn Addo. The antibodies which developed against the virus were still detectable after six months. Addo is convinced, "With this, a single vaccine could provide lasting protection against Ebola." The infectious disease specialist, who works for the German Center for Infection Research at the University Medical Center Hamburg Eppendorf in Hamburg, led the trial in Hamburg.

4 May 2016

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

The Gutenberg Research College of Johannes Gutenberg University Mainz has chosen to give the 2016 Gutenberg Research Award to American biomedical researcher Dr. Vishva Dixit for his groundbreaking work in the field of programmed cell death.

4 May 2016

Understanding effects of freeze-thawing, intravenous delivery on MSC function

Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases can be fully determined, the effects of freeze-thawing and intravenous delivery on MSC function must be understood.

3 May 2016

Researchers discover new function of genes in Fanconi anemia pathway

Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway - a finding that could have implications for development of new therapies to treat this disorder and some cancers.

3 May 2016

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Exercise can have a positive influence on certain symptoms of multiple sclerosis: Patients who do yoga and aquatic exercise suffer less from fatigue, depression and paresthesia, as reported by researchers from the University of Basel and the Psychiatric University Clinics Basel in a joint study with colleagues in Iran.

3 May 2016

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Research led by SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism and schizophrenia.

3 May 2016

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

The cannabinoid type 2 receptor - also called "CB2 receptor" - is a special membrane protein. Its function is to receive chemical signals that control cellular activity. "Until now, this receptor was considered part of the immune system without function in nerve cells.

3 May 2016

Immune System News and Research

ITJ researchers develop new hydrating beverage for athletes

Enzyme previously thought beneficial could pose threat to developing embryos

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Early viral respiratory infections may increase type 1 diabetes risk in children

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Human milk hormones may play vital role in shaping healthy infant microbiome

Candida yeast infections more common in men with schizophrenia or bipolar disorder

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

Respiratory tract infection in infants linked with increased T1D risk

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Real risk of rebound syndrome following fingolimod cessation for MS

New study links cathepsin S protein to tear secretion in Sjogren's syndrome patients

Ebola vaccine shows promise in clinical trials

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

Understanding effects of freeze-thawing, intravenous delivery on MSC function

Researchers discover new function of genes in Fanconi anemia pathway

Yoga, aquatic exercise have positive influence on multiple sclerosis symptoms

Brain receptor that initiates adolescent synaptic pruning appears to go awry in autism, schizophrenia

Study shows cannabinoid type 2 receptor plays vital role in signal processing of the brain

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